Detalhe da pesquisa
1.
Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial.
Lancet
; 397(10271): 281-292, 2021 01 23.
Artigo
Inglês
| MEDLINE | ID: mdl-33485453
2.
SLFN11 informs on standard of care and novel treatments in a wide range of cancer models.
Br J Cancer
; 124(5): 951-962, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33339894
3.
Retrospective analysis of Schlafen11 (SLFN11) to predict the outcomes to therapies affecting the DNA damage response.
Br J Cancer
; 125(12): 1666-1676, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34663950
4.
Evaluation of UV-C Decontamination of Clinical Tissue Sections for Spatially Resolved Analysis by Mass Spectrometry Imaging (MSI).
Anal Chem
; 93(5): 2767-2775, 2021 02 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33474935
5.
pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.
Br J Cancer
; 119(10): 1233-1243, 2018 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30385821
6.
The psychological health and well-being experiences of female military veterans: a systematic review of the qualitative literature.
J R Army Med Corps
; 163(5): 311-318, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28356493
7.
A 5-Year Review of a Tracheostomy Quality Improvement Initiative: Reducing Adverse Event Frequency and Severity.
Otolaryngol Head Neck Surg
; 2024 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38529665
8.
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation.
J Clin Invest
; 134(2)2024 Jan 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37934611
9.
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment.
Nat Commun
; 15(1): 1700, 2024 Feb 24.
Artigo
Inglês
| MEDLINE | ID: mdl-38402224
10.
Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach.
Mol Ther
; 20(10): 1953-67, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22760542
11.
'She's my sister-in-law, my visitor, my friend' -- challenges of staff identity in home follow-up in an HIV trial in Western Kenya.
Dev World Bioeth
; 13(1): 21-9, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23521821
12.
Therapy professionals in critical care: A UK wide workforce survey.
J Intensive Care Soc
; 24(1): 24-31, 2023 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-36874286
13.
Epitope Lability of Phosphorylated Biomarkers of the DNA Damage Response Pathway Results in Increased Vulnerability to Effects of Delayed or Incomplete Formalin Fixation.
J Histochem Cytochem
; 71(5): 237-257, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37119278
14.
Relevance of ATM Status in Driving Sensitivity to DNA Damage Response Inhibitors in Patient-Derived Xenograft Models.
Cancers (Basel)
; 15(16)2023 Aug 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37627223
15.
ATR Inhibitor AZD6738 (Ceralasertib) Exerts Antitumor Activity as a Monotherapy and in Combination with Chemotherapy and the PARP Inhibitor Olaparib.
Cancer Res
; 82(6): 1140-1152, 2022 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35078817
16.
Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance.
Clin Cancer Res
; 28(20): 4536-4550, 2022 10 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35921524
17.
Integration and functional performance of a decellularised porcine superflexor tendon graft in an ovine model of anterior cruciate ligament reconstruction.
Biomaterials
; 279: 121204, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34736146
18.
Exploration of therapists' views of practice within critical care.
BMJ Open Respir Res
; 8(1)2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34750167
19.
Early antiviral treatment in outpatients with COVID-19 (FLARE): a structured summary of a study protocol for a randomised controlled trial.
Trials
; 22(1): 193, 2021 Mar 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33685502
20.
Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study.
Clin Cancer Res
; 27(19): 5213-5224, 2021 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34301752