Pesquisa | Secretaria de Estado da Saúde

1.

Sister DNA Entrapment between Juxtaposed Smc Heads and Kleisin of the Cohesin Complex.

Chapard, Christophe; Jones, Robert; van Oepen, Till; Scheinost, Johanna C; Nasmyth, Kim.

Mol Cell ; 75(2): 224-237.e5, 2019 07 25.

Artigo Inglês | MEDLINE | ID: mdl-31201089

2.

Mechanisms and therapeutic implications of hypermutation in gliomas.

Touat, Mehdi; Li, Yvonne Y; Boynton, Adam N; Spurr, Liam F; Iorgulescu, J Bryan; Bohrson, Craig L; Cortes-Ciriano, Isidro; Birzu, Cristina; Geduldig, Jack E; Pelton, Kristine; Lim-Fat, Mary Jane; Pal, Sangita; Ferrer-Luna, Ruben; Ramkissoon, Shakti H; Dubois, Frank; Bellamy, Charlotte; Currimjee, Naomi; Bonardi, Juliana; Qian, Kenin; Ho, Patricia; Malinowski, Seth; Taquet, Leon; Jones, Robert E; Shetty, Aniket; Chow, Kin-Hoe; Sharaf, Radwa; Pavlick, Dean; Albacker, Lee A; Younan, Nadia; Baldini, Capucine; Verreault, Maïté; Giry, Marine; Guillerm, Erell; Ammari, Samy; Beuvon, Frédéric; Mokhtari, Karima; Alentorn, Agusti; Dehais, Caroline; Houillier, Caroline; Laigle-Donadey, Florence; Psimaras, Dimitri; Lee, Eudocia Q; Nayak, Lakshmi; McFaline-Figueroa, J Ricardo; Carpentier, Alexandre; Cornu, Philippe; Capelle, Laurent; Mathon, Bertrand; Barnholtz-Sloan, Jill S; Chakravarti, Arnab.

Nature ; 580(7804): 517-523, 2020 04.

Artigo Inglês | MEDLINE | ID: mdl-32322066

3.

c-Jun overexpression in CAR T cells induces exhaustion resistance.

Lynn, Rachel C; Weber, Evan W; Sotillo, Elena; Gennert, David; Xu, Peng; Good, Zinaida; Anbunathan, Hima; Lattin, John; Jones, Robert; Tieu, Victor; Nagaraja, Surya; Granja, Jeffrey; de Bourcy, Charles F A; Majzner, Robbie; Satpathy, Ansuman T; Quake, Stephen R; Monje, Michelle; Chang, Howard Y; Mackall, Crystal L.

Nature ; 576(7786): 293-300, 2019 12.

Artigo Inglês | MEDLINE | ID: mdl-31802004

4.

Systemic anticancer therapy for urothelial carcinoma: UK oncologists' perspective.

Jones, Robert J; Crabb, Simon J; Linch, Mark; Birtle, Alison J; McGrane, John; Enting, Deborah; Stevenson, Robert; Liu, Kin; Kularatne, Bihani; Hussain, Syed A.

Br J Cancer ; 130(6): 897-907, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-38191608

5.

Talazoparib plus enzalutamide in men with first-line metastatic castration-resistant prostate cancer (TALAPRO-2): a randomised, placebo-controlled, phase 3 trial.

Agarwal, Neeraj; Azad, Arun A; Carles, Joan; Fay, Andre P; Matsubara, Nobuaki; Heinrich, Daniel; Szczylik, Cezary; De Giorgi, Ugo; Young Joung, Jae; Fong, Peter C C; Voog, Eric; Jones, Robert J; Shore, Neal D; Dunshee, Curtis; Zschäbitz, Stefanie; Oldenburg, Jan; Lin, Xun; Healy, Cynthia G; Di Santo, Nicola; Zohren, Fabian; Fizazi, Karim.

Lancet ; 402(10398): 291-303, 2023 07 22.

Artigo Inglês | MEDLINE | ID: mdl-37285865

6.

A plug and play microfluidic platform for standardized sensitive low-input chromatin immunoprecipitation.

Dirks, René A M; Thomas, Peter C; Wu, Haoyu; Jones, Robert C; Stunnenberg, Hendrik G; Marks, Hendrik.

Genome Res ; 31(5): 919-933, 2021 05.

Artigo Inglês | MEDLINE | ID: mdl-33707229

7.

Ontogeny of Human Liver Aldehyde Oxidase: Developmental Changes and Implications for Drug Metabolism.

Subash, Sandhya; Singh, Dilip K; Ahire, Deepak; Khojasteh, S Cyrus; Murray, Bernard P; Zientek, Michael A; Jones, Robert S; Kulkarni, Priyanka; Zubair, Faizan; Smith, Bill J; Heyward, Scott; Leeder, J Steven; Prasad, Bhagwat.

Mol Pharm ; 2024 May 08.

Artigo Inglês | MEDLINE | ID: mdl-38717252

8.

PhyloFisher: A phylogenomic package for resolving eukaryotic relationships.

Tice, Alexander K; Zihala, David; Pánek, Tomás; Jones, Robert E; Salomaki, Eric D; Nenarokov, Serafim; Burki, Fabien; Eliás, Marek; Eme, Laura; Roger, Andrew J; Rokas, Antonis; Shen, Xing-Xing; Strassert, Jürgen F H; Kolísko, Martin; Brown, Matthew W.

PLoS Biol ; 19(8): e3001365, 2021 08.

Artigo Inglês | MEDLINE | ID: mdl-34358228

9.

Living in the cracks: Two novel genera of Variosea (Amoebozoa) discovered on an urban sidewalk.

Fry, Nicholas; Schuler, Gabriel A; Jones, Robert E; Kooienga, Peter G; Jira, Violet; Shepherd, Maggie; Tice, Alexander K; Brown, Matthew W.

J Eukaryot Microbiol ; 71(3): e13020, 2024.

Artigo Inglês | MEDLINE | ID: mdl-38240465

10.

Impact of Share 35 liver transplantation allocation in Australia and New Zealand.

Fink, Michael A; Gow, Paul J; McCaughan, Geoffrey W; Hodgkinson, Peter; Chen, John; McCall, John; Jaques, Bryon; Crawford, Michael; Strasser, Simone I; Hardikar, Winita; Brooke-Smith, Mark; Starkey, Graham; Jeffrey, Gary P; Gane, Ed; Stormon, Michael; Evans, Helen; Tallis, Caroline; Byrne, Amanda J; Jones, Robert M.

Clin Transplant ; 38(1): e15203, 2024 01.

Artigo Inglês | MEDLINE | ID: mdl-38088459

11.

A Near-Infrared Luminescent Cr(III) N-Heterocyclic Carbene Complex.

Jones, Robert W; Cowin, Rory A; Ivalo, Iona I; Chekulaev, Dimitri; Roseveare, Thomas M; Rice, Craig R; Weinstein, Julia A; Elliott, Paul I P; Scattergood, Paul A.

Inorg Chem ; 63(19): 8526-8530, 2024 May 13.

Artigo Inglês | MEDLINE | ID: mdl-38696219

12.

Cost-effectiveness analysis for avelumab first-line maintenance treatment of advanced urothelial carcinoma in Scotland.

Critchlow, Simone; Bullement, Ash; Crabb, Simon; Jones, Robert; Christoforou, Katerina; Amin, Amerah; Xiao, Ying; Kapetanakis, Venediktos; Benedict, Ágnes; Chang, Jane; Kearney, Mairead; Eccleston, Anthony.

Future Oncol ; 20(8): 459-470, 2024 Mar.

Artigo Inglês | MEDLINE | ID: mdl-37529943

13.

TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer.

Agarwal, Neeraj; Rinaldetti, Sebastien; Cheikh, Bassem B; Zhou, Qiong; Hass, Evan P; Jones, Robert T; Joshi, Molishree; LaBarbera, Daniel V; Knott, Simon R V; Cech, Thomas R; Theodorescu, Dan.

Proc Natl Acad Sci U S A ; 118(38)2021 09 21.

Artigo Inglês | MEDLINE | ID: mdl-34518220

14.

Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development.

Golding, Adam P; Ferrier, Benjamin; New, Laura A; Lu, Peihua; Martin, Claire E; Shata, Erka; Jones, Robert A; Moorehead, Roger A; Jones, Nina.

J Mammary Gland Biol Neoplasia ; 28(1): 19, 2023 07 21.

Artigo Inglês | MEDLINE | ID: mdl-37479911

15.

Temporary treatment cessation versus continuation of first-line tyrosine kinase inhibitor in patients with advanced clear cell renal cell carcinoma (STAR): an open-label, non-inferiority, randomised, controlled, phase 2/3 trial.

Brown, Janet E; Royle, Kara-Louise; Gregory, Walter; Ralph, Christy; Maraveyas, Anthony; Din, Omar; Eisen, Timothy; Nathan, Paul; Powles, Tom; Griffiths, Richard; Jones, Robert; Vasudev, Naveen; Wheater, Matthew; Hamid, Abdel; Waddell, Tom; McMenemin, Rhona; Patel, Poulam; Larkin, James; Faust, Guy; Martin, Adam; Swain, Jayne; Bestall, Janine; McCabe, Christopher; Meads, David; Goh, Vicky; Min Wah, Tze; Brown, Julia; Hewison, Jenny; Selby, Peter; Collinson, Fiona.

Lancet Oncol ; 24(3): 213-227, 2023 03.

Artigo Inglês | MEDLINE | ID: mdl-36796394

16.

Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol.

Attard, Gerhardt; Murphy, Laura; Clarke, Noel W; Sachdeva, Ashwin; Jones, Craig; Hoyle, Alex; Cross, William; Jones, Robert J; Parker, Christopher C; Gillessen, Silke; Cook, Adrian; Brawley, Chris; Gilson, Clare; Rush, Hannah; Abdel-Aty, Hoda; Amos, Claire L; Murphy, Claire; Chowdhury, Simon; Malik, Zafar; Russell, J Martin; Parkar, Nazia; Pugh, Cheryl; Diaz-Montana, Carlos; Pezaro, Carmel; Grant, Warren; Saxby, Helen; Pedley, Ian; O'Sullivan, Joe M; Birtle, Alison; Gale, Joanna; Srihari, Narayanan; Thomas, Carys; Tanguay, Jacob; Wagstaff, John; Das, Prantik; Gray, Emma; Alzouebi, Mymoona; Parikh, Omi; Robinson, Angus; Montazeri, Amir H; Wylie, James; Zarkar, Anjali; Cathomas, Richard; Brown, Michael D; Jain, Yatin; Dearnaley, David P; Mason, Malcolm D; Gilbert, Duncan; Langley, Ruth E; Millman, Robin.

Lancet Oncol ; 24(5): 443-456, 2023 05.

Artigo Inglês | MEDLINE | ID: mdl-37142371

17.

Role of the ST6GAL1 sialyltransferase in regulating ovarian cancer cell metabolism.

Jones, Robert B; Silva, Austin D; Ankenbauer, Katherine E; Britain, Colleen M; Chakraborty, Asmi; Brown, Jamelle A; Ballinger, Scott W; Bellis, Susan L.

Glycobiology ; 33(8): 626-636, 2023 10 06.

Artigo Inglês | MEDLINE | ID: mdl-37364046

18.

Direct Determination of the Rate of Intersystem Crossing in a Near-IR Luminescent Cr(III) Triazolyl Complex.

Jones, Robert W; Auty, Alexander J; Wu, Guanzhi; Persson, Petter; Appleby, Martin V; Chekulaev, Dimitri; Rice, Craig R; Weinstein, Julia A; Elliott, Paul I P; Scattergood, Paul A.

J Am Chem Soc ; 145(22): 12081-12092, 2023 Jun 07.

Artigo Inglês | MEDLINE | ID: mdl-37224437

19.

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer.

Glaviano, Antonino; Foo, Aaron S C; Lam, Hiu Y; Yap, Kenneth C H; Jacot, William; Jones, Robert H; Eng, Huiyan; Nair, Madhumathy G; Makvandi, Pooyan; Geoerger, Birgit; Kulke, Matthew H; Baird, Richard D; Prabhu, Jyothi S; Carbone, Daniela; Pecoraro, Camilla; Teh, Daniel B L; Sethi, Gautam; Cavalieri, Vincenzo; Lin, Kevin H; Javidi-Sharifi, Nathalie R; Toska, Eneda; Davids, Matthew S; Brown, Jennifer R; Diana, Patrizia; Stebbing, Justin; Fruman, David A; Kumar, Alan P.

Mol Cancer ; 22(1): 138, 2023 08 18.

Artigo Inglês | MEDLINE | ID: mdl-37596643

20.

A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer.

Kristeleit, Rebecca; Plummer, Ruth; Jones, Robert; Carter, Louise; Blagden, Sarah; Sarker, Debashis; Arkenau, Tobias; Evans, Thomas R Jeffry; Danson, Sarah; Symeonides, Stefan N; Veal, Gareth J; Klencke, Barbara J; Kowalski, Mark M; Banerji, Udai.

Br J Cancer ; 129(1): 38-45, 2023 07.

Artigo Inglês | MEDLINE | ID: mdl-37120671

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