Detalhe da pesquisa
1.
Chemosensitization and radiosensitization of human lung and colon cancers by antimitotic agent, ABT-751, in athymic murine xenograft models of subcutaneous tumor growth.
Cancer Chemother Pharmacol
; 59(6): 725-32, 2007 May.
Artigo
Inglês
| MEDLINE | ID: mdl-16967299
2.
Antitumor activity of orally bioavailable farnesyltransferase inhibitor, ABT-100, is mediated by antiproliferative, proapoptotic, and antiangiogenic effects in xenograft models.
Clin Cancer Res
; 11(8): 3045-54, 2005 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15837760
3.
Preclinical Evaluation of an Anti-Nectin-4 ImmunoPET Reagent in Tumor-Bearing Mice and Biodistribution Studies in Cynomolgus Monkeys.
Mol Imaging Biol
; 18(5): 768-75, 2016 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27122234
4.
Identification of 2-[2-[2-(5-bromo-2- methoxyphenyl)-ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole (ML00253764), a small molecule melanocortin 4 receptor antagonist that effectively reduces tumor-induced weight loss in a mouse model.
J Med Chem
; 47(7): 1602-4, 2004 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-15027849
5.
The anti-Fn14 antibody BIIB036 inhibits tumor growth in xenografts and patient derived primary tumor models and enhances efficacy of chemotherapeutic agents in multiple xenograft models.
Cancer Biol Ther
; 13(9): 812-21, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22669574
6.
Development of an Fn14 agonistic antibody as an anti-tumor agent.
MAbs
; 3(4): 362-75, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21697654
7.
A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity.
MAbs
; 3(3): 273-88, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21393993