RESUMO
Foodborne Campylobacter is recognized as the leading causes of the bacterial diarrheal illness in both developing and developed countries. C. jejuni and C. coli caused 95% of the human campylobacterisosis. Bacteria culture has been recognized as the "Gold standard" for the diagnosis of the Campylobacter infection. The National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention coordinated the experienced researchers from China National Center for Food Safety Risk Assessment and other local Centers for Disease Control and Prevention to write up the standards for entitled Isolation and Identification of Campylobacter jejuni and Campylobacter coli (T/CPMA 006-2019). The standard is drafted with principles of emphasizing the scientific, normative, applicability and feasible nature. This group standard recommended the procedures and steps for the isolation and identification of C. jejuni and C.coli from variant samples. The standard aims to improve the capacity for Campylobacter identification in China.
Assuntos
Infecções por Campylobacter/microbiologia , Campylobacter coli/isolamento & purificação , Campylobacter jejuni/isolamento & purificação , China , Disenteria/microbiologia , HumanosRESUMO
The effect of 5-hydroxytryptophan (5-HTP), the serotonin precursor, on food intake in rats was investigated in this study. 5-HTP (100 mg/kg, i.p.) reduced food intake by 68.9% of control level. The anorectic effect of 5-HTP was antagonized by cyproheptadine (CYP, 4 mg/kg, i.p.), a serotonin receptor blockade. However, the anorectic effect of 5-HTP was also antagonized by propranolol (PROP 1mg/kg, i.p.) and sulpiride (SULP, 20 mg/kg, i.p.), while Pinodol (PIN 2mg/kg, i.p.) and Haloperidol (HAL 0.5 mg/kg, i.p) did not affect the suppressive effect of 5-HTP on food intake by 5-HTP. These results indicates that the anorectic action of 5-HTP was mediated by the serotonergic mechanism through 5-HT1 and 5-HT2 receptors.