RESUMO
BACKGROUND: Using a validated instrument to measure palliative care (PC) educational needs of health professionals is an important step in understanding how best to educate a well-versed PC workforce within a national health system. The End-of-life Professional Caregiver Survey (EPCS) was developed to measure U.S. interprofessional PC educational needs and has been validated for use in Brazil and China. As part of a larger research project, this study aimed to culturally adapt and psychometrically test the EPCS among physicians, nurses, and social workers practicing in Jamaica. METHODS: Face validation involved expert review of the EPCS with recommendations for linguistic item modifications. Content validation was carried out by six Jamaica-based experts who completed a formal content validity index (CVI) for each EPCS item to ascertain relevancy. Health professionals practicing in Jamaica (n = 180) were recruited using convenience and snowball sampling to complete the updated 25-item EPCS (EPCS-J). Internal consistency reliability was assessed using Cronbach's [Formula: see text] coefficient and McDonald's [Formula: see text]. Construct validity was examined through confirmatory factor analysis (CFA) and exploratory factor analysis (EFA). RESULTS: Content validation led to elimination of three EPCS items based on a CVI < 0.78. Cronbach's [Formula: see text] ranged from 0.83 to 0.91 and McDonald's [Formula: see text] ranged from 0.73 to 0.85 across EPCS-J subscales indicating good internal consistency reliability. The corrected item-total correlation for each EPCS-J item was > 0.30 suggesting good reliability. The CFA demonstrated a three-factor model with acceptable fit indices (RMSEA = 0.08, CFI = 0.88, SRMR = 0.06). The EFA determined a three-factor model had the best model fit, with four items moved into the effective patient care subscale from the other two EPCS-J subscales based on factor loading. CONCLUSIONS: The psychometric properties of the EPCS-J resulted in acceptable levels of reliability and validity indicating that this instrument is suitable for use in measuring interprofessional PC educational needs in Jamaica.
Assuntos
Cuidadores , Humanos , Psicometria/métodos , Reprodutibilidade dos Testes , Jamaica , Inquéritos e QuestionáriosRESUMO
PURPOSE: To determine the research output of Caribbean nurses and midwives. METHODS: We searched the Scopus database to identify publications by Caribbean nurses and midwives during the period 2000-2020. Publications were included in the analysis if they had at least one author who was either a nurse or midwife and affiliated with a Caribbean geographic location. All publication types and languages were included in the analysis. Organization analysis and collaboration networks were created using the VOS Viewer application. FINDINGS: The number of Scopus publications by Caribbean nurses and midwives progressively grew from 22 in 2000 to 584 in 2020. Cuba recorded the highest number of nursing research publications (319) followed by Jamaica (92), and Puerto Rico (59). Most publishing institutions were universities. The University of the West Indies (Jamaica) ranked highest with 15.2% of publications, followed by Universidad de Ciencias Médicas de La Habana with 14.4% of publications, Universidad de Puerto Rico ranked third with 9.8% of publications. The majority of publications (83.6%) were peer reviewed research articles, while review articles accounted for 9.8% of publications. Six out of the ten journals that published most research done by Caribbean nurse researchers were Cuban journals which published a total of n = 250 (75.8%) articles. All six journals had no impact factor and had low cite scores. CONCLUSIONS: Our analysis of bibliometric indicators suggest that recent and steady growth in nursing and midwifery research in the Caribbean has had low visibility. Equipping nurses and midwives with the necessary knowledge and skills to lead, teach, and conduct high quality research through doctorate level education is an imperative for increasing research productivity among Caribbean nurses and midwives. CLINICAL RELEVANCE: Nursing and midwifery research is critical for evidence-based nursing and midwifery practice. High quality and context specific research evidence will enable Caribbean nurses and midwives to provide quality and culturally sensitive nursing and midwifery care and contribute to evidence informed policy decisions.
Assuntos
Tocologia , Pesquisa em Enfermagem , Bibliometria , Região do Caribe , Feminino , Humanos , Gravidez , Publicações , Índias OcidentaisRESUMO
BACKGROUND: Practice guidelines aim to improve the standard of care for people living with HIV/AIDS. Successfully implementing guidelines requires tailoring them to populations served and to social and organizational influences on care. AIMS: To examine dimensions of context, which nurses and midwives described as having a significant impact on their care of patients living with HIV/AIDS in Kenya, Uganda, South Africa, and Jamaica and to determine whether HIV/AIDS guidelines include adaptations congruent with these dimensions of context. METHODS: Two sets of data were used. The first came from a qualitative study. In-depth interviews were conducted with purposively selected nurses, midwives, and nurse managers from 21 districts in four study countries. A coding framework was iteratively developed and themes inductively identified. Context dimensions were derived from these themes. A second data set of published guidelines for HIV/AIDS care was then assembled. Guidelines were identified through Google and PubMed searches. Using a deductive integrative analysis approach, text related to context dimensions was extracted from guidelines and categorized into problem and strategy statements. RESULTS: Ninety-six individuals participated in qualitative interviews. Four discrete dimensions of context were identified: health workforce adequacy, workplace exposure risk, workplace consequences for nurses living with HIV/AIDS, and the intersection of work and family life. Guidelines most often acknowledged health human resource constraints and presented mitigation strategies to offset them, and least often discussed workplace consequences and the intersections of family and work life. LINKING EVIDENCE TO ACTION: Guidelines should more consistently acknowledge diverse implementation contexts, propose how recommendations can be adapted to these realities, and suggest what role frontline healthcare providers have in realizing the structural changes necessary for healthier work environments and better patient care. Guideline recommendations should include more explicit advice on adapting their recommendations to different care conditions.
Assuntos
Atitude do Pessoal de Saúde , Guias como Assunto/normas , Infecções por HIV/psicologia , Enfermeiras e Enfermeiros/psicologia , Padrão de Cuidado/normas , Adulto , Feminino , Infecções por HIV/enfermagem , Infecções por HIV/prevenção & controle , Humanos , Jamaica , Quênia , Masculino , Pessoa de Meia-Idade , Admissão e Escalonamento de Pessoal/normas , Pesquisa Qualitativa , África do Sul , Uganda , Precauções Universais/economia , Precauções Universais/instrumentação , Local de Trabalho/psicologiaRESUMO
Background: The COVID-19 pandemic has exposed nurses to more stress and inability to practice self-care activities. These have resulted in conditions that threaten their health, well-being, and ability to work. Nurses' lack of self-care can predispose them to chronic health conditions and staff burnout which may adversely affect patient care. The panacea for this concern is a deliberate effort to promote holistic health and wellbeing through self-care activities targeted towards physical, mental, social and spiritual aspects of nurses. The purpose of this study was to explore factors influencing self-care practices among registered nurses during COVID-19 pandemic. Methods: Convenience sampling was used to select 294 nurses from four urban hospitals in Kingston Jamaica. A questionnaire was utilized for data collection. Logistical regression analysis was conducted using Statistical Package for Social Sciences (SPSS) software version 22.0. Ethical approval was obtained. Results: The response rate was 46% (Out of 294 questionnaires distributed, only 136 were returned). Although 93% of participants engage in self-care activities during COVID-19 pandemic, only 45% practiced self-care on a daily basis. Half of the participants (50%) practiced self care activities sometimes while 5% do not engage in self care practices. Activities that promote psychological and social wellbeing were not common among participants. Most self care activities were towards the promotion of physical health and wellbeing. Majority of respondents indicated that excess workload, fatigue, lack of time and poor remuneration are factors that prevent their practice of self-care. Findings also revealed that demographic data such as age, sex, income, gender and ethnic background influences self-care practices among nurses. Conclusion: The practice of self care among nurses needs improvements. Although respondents engage in some activities to care for self, majority are not consistent with this practice.
Assuntos
Esgotamento Profissional , COVID-19 , Enfermeiras e Enfermeiros , Humanos , Autocuidado , Pandemias , Esgotamento Profissional/psicologia , Inquéritos e QuestionáriosRESUMO
PURPOSE: The purpose of this study was to identify the ways in which urban Jamaican mothers influence their adolescent daughters' sexual beliefs and behaviors in order to incorporate them into the design of a family-based human immunodeficiency virus (HIV) risk reduction intervention program. DESIGN: Focus groups were conducted with 46 14- to 18-year-old adolescent girls and 30 mothers or female guardians of adolescent girls recruited from community-based organizations in and around Kingston and St. Andrew, Jamaica. Separate focus groups were held with mothers and daughters; each included 6 to 10 participants. Focus group sessions were scripted, led by teams that included trained Jamaican and American facilitators and note-takers, and audio-taped to ensure data accuracy. Data were analyzed using qualitative content analysis. FINDINGS: Four major maternal influences were identified: mother-daughter relationship quality, mother-daughter sexual communication, monitoring or supervision, and maternal sexual role modeling. Mothers' and daughters' reports were consistent; both groups identified positive and negative influences within each category. CONCLUSIONS: Some maternal influences were positive and health promoting; others were negative and promoted unsafe sexual activity and risk for HIV and other sexually transmitted infections. These influences were incorporated into the design of a culture-specific family-based HIV risk reduction intervention tailored to the needs of urban Jamaican adolescent girls and their mothers. CLINICAL RELEVANCE: In order to be effective, family-based HIV risk reduction interventions should be theory based and tailored to the target audience. The four maternal influences identified in this formative study were incorporated into the subsequent intervention design.
Assuntos
Comportamento do Adolescente/psicologia , Atitude Frente a Saúde , Infecções por HIV/prevenção & controle , Relações Mãe-Filho , Assunção de Riscos , Comportamento Sexual/psicologia , Saúde da População Urbana , Adolescente , Adulto , Atitude , Feminino , Grupos Focais , Humanos , Jamaica , Comportamento Materno/psicologia , Pessoa de Meia-Idade , Pesquisa Qualitativa , Fatores SocioeconômicosRESUMO
BACKGROUND: The term 'inequities' refers to avoidable differences rooted in injustice. This review examined whether or not, and how, quantitative studies identifying inequalities in risk factors and health service utilization for asthma explicitly addressed underlying inequities. Asthma was chosen because recent decades have seen strong increases in asthma prevalence in many international settings, and inequalities in risk factors and related outcomes. METHODS: A review was conducted of studies that identified social inequalities in asthma-related outcomes or health service use in adult populations. Data were extracted on use of equity terms (objective evidence), and discussion of equity issues without using the exact terms (subjective evidence). RESULTS: Of the 219 unique articles retrieved, 21 were eligible for inclusion. None used the terms equity/inequity. While all but one article traced at least partial pathways to inequity, only 52% proposed any intervention and 55% of these interventions focused exclusively on the more proximal, clinical level. CONCLUSIONS: Without more in-depth and systematic examination of inequities underlying asthma prevalence, quantitative studies may fail to provide the evidence required to inform equity-oriented interventions to address underlying circumstances restricting opportunities for health.
Assuntos
Asma/epidemiologia , Serviços de Saúde/estatística & dados numéricos , Adulto , Asma/etiologia , Asma/terapia , Humanos , Fatores de Risco , Fatores Socioeconômicos , Resultado do TratamentoRESUMO
PURPOSE: The purpose of this study was to describe the relationships between adolescent girls and older male sexual partners in urban Kingston, Jamaica, and identify the human immunodeficiency virus (HIV)-related sexual risks that occur within these relationships. DESIGN: The study employed a descriptive qualitative design. METHODS: Data were collected through focus groups and individual interviews conducted with 43 late adolescent girls (18-21 years old). An age-discordant relationship was defined as a sexual relationship between a Jamaican adolescent female and a man who was 2 or more years older. Data were analyzed using qualitative content analysis. FINDINGS: Age-discordant relationships were common and often began when girls were early adolescents. Both adolescent girls and older men tended to have multiple partners, and transactions of gifts, money, or resources from an older partner were expected and common. Older partners were highly influential in HIV-related risk behaviors. CONCLUSIONS: Age-discordant relationships need to be explicitly addressed in HIV prevention programs for adolescent girls in Jamaica. Further, the implications of gift-giving, informal sexual transactions, and intradyadic power must be incorporated into strategies for reducing HIV-related sexual risk with older partners. Future studies should examine the perspectives of Jamaican men. CLINICAL RELEVANCE: This study found that many Jamaican adolescent girls engage in sexual relationships with older men and that the unique characteristics of these relationships may increase girls' risks for HIV and other sexually transmitted diseases. HIV risk reduction interventions for adolescent girls should address sexual risks associated with older male partners.
Assuntos
Infecções por HIV/transmissão , Assunção de Riscos , Comportamento Sexual/psicologia , Parceiros Sexuais , Saúde da População Urbana , Adolescente , Fatores Etários , Preservativos/estatística & dados numéricos , Feminino , Humanos , Jamaica , Masculino , Pesquisa Qualitativa , Comportamento Sexual/estatística & dados numéricos , Fatores Socioeconômicos , Adulto JovemRESUMO
BACKGROUND: Asthma is a significant public health problem in the Caribbean. Prevalence surveys using standardized measures of asthma provide valid prevalence estimates to facilitate regional and international comparisons and monitoring of trends. This paper describes methods used in the Jamaica Asthma and Allergies National Prevalence Survey, challenges associated with this survey and strategies used to overcome these challenges. METHODS/DESIGN: An island wide, cross-sectional, community-based survey of asthma, asthma symptoms and allergies was done among adults and children using the European Community Respiratory Health Survey Questionnaire for adults and the International Study of Asthma and Allergies in Children. Stratified multi-stage cluster sampling was used to select 2, 163 adults aged 18 years and older and 2, 017 children aged 2-17 years for the survey. The Kish selection table was used to select one adult and one child per household. Data analysis accounted for sampling design and prevalence estimates were weighted to produce national estimates. DISCUSSION: The Jamaica Asthma and Allergies National Prevalence Survey is the first population- based survey in the Caribbean to determine the prevalence of asthma and allergies both in adults and children using standardized methods. With response rates exceeding 80% in both groups, this approach facilitated cost-effective gathering of high quality asthma prevalence data that will facilitate international and regional comparison and monitoring of asthma prevalence trends. Another unique feature of this study was the partnership with the Ministry of Health in Jamaica, which ensured the collection of data relevant for decision-making to facilitate the uptake of research evidence. The findings of this study will provide important data on the burden of asthma and allergies in Jamaica and contribute to evidence-informed planning of comprehensive asthma management and education programs.
Assuntos
Asma/epidemiologia , Hipersensibilidade/epidemiologia , Programas de Rastreamento/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Análise por Conglomerados , Estudos Transversais , Feminino , Inquéritos Epidemiológicos/métodos , Humanos , Jamaica/epidemiologia , Masculino , Pessoa de Meia-Idade , Programas Nacionais de Saúde , Prevalência , Inquéritos e Questionários , Adulto JovemRESUMO
The purpose of this article is to describe the results from an elicitation research study addressing the multisystem-level factors that contribute to HIV risk among Jamaican adolescents. Focus group and survey data were determined from parents, adolescents, and teachers in Kingston, Jamaica, from 2004 and 2005. Guided by an ecological extension of the Theory of Planned Behavior, focus groups and survey questionnaires identified cultural factors at the individual, family, and societal levels that significantly influence Jamaican adolescents' behavioral, normative, and control beliefs related to sexual behaviors that contribute to risk for HIV and other sexually transmitted infections. Although some factors were similar to those reported among adolescents living in the United States, others were culture-specific influences and beliefs that were unique to Jamaica. Results from the current study could contribute to the development of theory-based, culture-specific HIV risk-reduction interventions for use with Jamaican adolescents.
Assuntos
Comportamento do Adolescente/etnologia , Atitude Frente a Saúde/etnologia , Infecções por HIV , Conhecimentos, Atitudes e Prática em Saúde , Assunção de Riscos , Comportamento Sexual/etnologia , Adolescente , Adulto , Docentes , Feminino , Grupos Focais , Infecções por HIV/etnologia , Infecções por HIV/prevenção & controle , Comportamentos Relacionados com a Saúde/etnologia , Necessidades e Demandas de Serviços de Saúde , Humanos , Controle Interno-Externo , Jamaica/epidemiologia , Masculino , Papel do Profissional de Enfermagem , Pesquisa Metodológica em Enfermagem , Pais/educação , Pais/psicologia , Teoria Psicológica , Psicologia do Adolescente , Comportamento de Redução do Risco , Valores Sociais , Inquéritos e QuestionáriosRESUMO
BACKGROUND: The enormous impact of HIV on communities and health services in Sub-Saharan Africa and the Caribbean has especially affected nurses, who comprise the largest proportion of the health workforce in low- and middle-income countries (LMICs). Strengthening action-based leadership for and by nurses is a means to improve the uptake of evidence-informed practices for HIV care. METHODS: A prospective quasi-experimental study in Jamaica, Kenya, Uganda and South Africa examined the impact of establishing multi-stakeholder leadership hubs on evidence-informed HIV care practices. Hub members were engaged through a participatory action research (PAR) approach. Three intervention districts were purposefully selected in each country, and three control districts were chosen in Jamaica, Kenya and Uganda. WHO level 3, 4 and 5 health care institutions and their employed nurses were randomly sampled. Self-administered, validated instruments measured clinical practices (reports of self and peers), quality assurance, work place policies and stigma at baseline and follow-up. Standardised average scores ranging from 0 to 1 were computed for clinical practices, quality assurance and work place policies. Stigma scores were summarised as 0 (no reports) versus 1 (one or more reports). Pre-post differences in outcomes between intervention and control groups were compared using the Mantel Haenszel chi-square for dichotomised stigma scores, and independent t tests for other measures. For South Africa, which had no control group, pre-post differences were compared using a Pearson chi-square and independent t test. Multivariate analysis was completed for Jamaica and Kenya. Hub members in all countries self-assessed changes in their capacity at follow-up; these were examined using a paired t test. RESULTS: Response rates among health care institutions were 90.2 and 80.4 % at baseline and follow-up, respectively. Results were mixed. There were small but statistically significant pre-post, intervention versus control district improvements in workplace policies and quality assurance in Jamaica, but these were primarily due to a decline in scores in the control group. There were modest improvements in clinical practices, workplace policies and quality assurance in South Africa (pre-post) (clinical practices of self-pre 0.67 (95 % CI, 0.62, 0.72) versus post 0.78 (95 % CI, 0.73-0.82), p = 0.002; workplace policies-pre 0.82 (95 % CI, 0.70, 0.85) versus post 0.87 (95 % CI, 0.84, 0.90), p = 0.001; quality assurance-pre 0.72 (95 % CI, 0.67, 0.77) versus post 0.84 (95 % CI, 0.80, 0.88)). There were statistically significant improvements in scores for nurses stigmatising patients (Jamaica reports of not stigmatising-pre-post intervention 33.9 versus 62.4 %, pre-post control 54.7 versus 64.4 %, p = 0.002-and Kenya pre-post intervention 35 versus 51.6 %, pre-post control 34.2 versus 47.8 %, p = 0.006) and for nurses being stigmatised (Kenya reports of no stigmatisation-pre-post intervention 23 versus 37.3 %, pre-post control 15.4 versus 27 %, p = 0.004). Multivariate results for Kenya and Jamaica were non-significant. Twelve hubs were established; 11 were active at follow-up. Hub members (n = 34) reported significant improvements in their capacity to address care gaps. CONCLUSIONS: Leadership hubs, comprising nurses and other stakeholders committed to change and provided with capacity building can collectively identify issues and act on strategies that may improve practice and policy. Overall, hubs did not provide the necessary force to improve the uptake of evidence-informed HIV care in their districts. If hubs are to succeed, they must be integrated within district health authorities and become part of formal, legal organisations that can regularise and sustain them.
Assuntos
Infecções por HIV/enfermagem , Liderança , Fortalecimento Institucional , Medicina Baseada em Evidências/organização & administração , Medicina Baseada em Evidências/normas , Feminino , Infecções por HIV/psicologia , Política de Saúde , Humanos , Jamaica , Quênia , Masculino , Relações Enfermeiro-Paciente , Processo de Enfermagem , Serviços de Saúde do Trabalhador/organização & administração , Serviços de Saúde do Trabalhador/normas , Avaliação de Resultados em Cuidados de Saúde , Preconceito , Prática Profissional/organização & administração , Prática Profissional/normas , Garantia da Qualidade dos Cuidados de Saúde , Melhoria de Qualidade , Estigma Social , África do Sul , Pesquisa Translacional Biomédica , UgandaRESUMO
As part of a multinational program of research, we undertook a community-based participatory research project in Jamaica to strengthen nurses' engagement in HIV and AIDS policy. Three leadership hubs were purposefully convened and included small groups of people (6-10) from diverse HIV and AIDS stakeholder groups in Jamaica: frontline nurses and nurse managers in primary and secondary care settings; researchers; health care decision makers; and other community members. People living with HIV or AIDS were among the hub members. Using a relational public health ethics framework, we outline some of the ethical challenges and opportunities experienced by the research team and the leadership hubs. Data included research assistant field notes and hub progress reports. Emerging ethical concerns were associated with relational personhood, social justice, relational autonomy, relational solidarity, and sustainability of the hub activities.
Assuntos
Pesquisa Participativa Baseada na Comunidade/ética , Ética em Pesquisa , Infecções por HIV , Enfermeiros Administradores , Enfermeiras e Enfermeiros , Saúde Pública/ética , Características de Residência , Síndrome da Imunodeficiência Adquirida , Atitude , Política de Saúde , Humanos , Relações Interpessoais , Jamaica , Justiça SocialRESUMO
OBJECTIVE: To determine the prevalence and severity of asthma and allergies as well as risk factors for asthma among Jamaican children aged 2-17 years. DESIGN: A cross-sectional, community-based prevalence survey using the International Study of Asthma and Allergies in Childhood questionnaire. The authors selected a representative sample of 2017 children using stratified, multistage cluster sampling design using enumeration districts as primary sampling units. SETTING: Jamaica, a Caribbean island with a total population of approximately 2.6 million, geographically divided into 14 parishes. PARTICIPANTS: Children aged 2-17 years, who were resident in private households. Institutionalised children such as those in boarding schools and hospitals were excluded from the survey. PRIMARY AND SECONDARY OUTCOME MEASURES: The prevalence and severity of asthma and allergy symptoms, doctor-diagnosed asthma and risk factors for asthma. RESULTS: Almost a fifth (19.6%) of Jamaican children aged 2-17 years had current wheeze, while 16.7% had self-reported doctor-diagnosed asthma. Both were more common among males than among females. The prevalence of rhinitis, hay fever and eczema among children was 24.5%, 25% and 17.3%, respectively. Current wheeze was more common among children with rhinitis in the last 12 months (44.3% vs 12.6%, p<0.001), hay fever (36.8% vs 13.8%, p<0.001) and eczema (34.1% vs 16.4%, p<0.001). Independent risk factors for current wheeze (ORs, 95% CI) were chest infections in the first year of life 4.83 (3.00 to 7.77), parental asthma 4.19 (2.8 to 6.08), rhinitis in the last 12 months 6.92 (5.16 to 9.29), hay fever 4.82 (3.62 to 6.41), moulds in the home 2.25 (1.16 to 4.45), cat in the home 2.44 (1.66 to 3.58) and dog in the home 1.81 (1.18 to 2.78). CONCLUSIONS: The prevalence of asthma and allergies in Jamaican children is high. Significant risk factors for asthma include chest infections in the first year of life, a history of asthma in the family, allergies, moulds and pets in the home.
RESUMO
BACKGROUND: Asthma is a significant public health problem in the Caribbean. Prevalence surveys using standardized measures of asthma provide valid prevalence estimates to facilitate regional and international comparisons and monitoring of trends. This paper describes methods used in the Jamaica Asthma and Allergies National Prevalence Survey, challenges associated with this survey and strategies used to overcome these challenges. METHODS/DESIGN: An island wide, cross-sectional, community-based survey of asthma, asthma symptoms and allergies was done among adults and children using the European Community Respiratory Health Survey Questionnaire for adults and the International Study of Asthma and Allergies in Children. Stratified multi-stage cluster sampling was used to select 2, 163 adults aged 18 years and older and 2, 017 children aged 2-17 years for the survey. The Kish selection table was used to select one adult and one child per household. Data analysis accounted for sampling design and prevalence estimates were weighted to produce national estimates.DISCUSSION: The Jamaica Asthma and Allergies National Prevalence Survey is the first population- based survey in the Caribbean to determine the prevalence of asthma and allergies both in adults and children using standardized methods. With response rates exceeding 80% in both groups, this approach facilitated cost-effective gathering of high quality asthma prevalence data that will facilitate international and regional comparison and monitoring of asthma prevalence trends. Another unique feature of this study was the partnership with the Ministry of Health in Jamaica, which ensured the collection of data relevant for decision-making to facilitate the uptake of research evidence. The findings of this study will provide important data on the burden of asthma and allergies in Jamaica and contribute to evidence-informed planning of comprehensive asthma management and education programs.
Assuntos
Criança , Adolescente , Adulto , Humanos , Asma , Asma/classificação , Asma/economia , JamaicaRESUMO
Our aims were to determine if the presence of anticardiolipin antibodies (aCL) is an independent risk factor for venous thromboembolism (VTE), myocardial infarction (MI) and stroke (CVA) and to estimate the prevalence of aCL among primiparae and its influence on pregnancy outcome. aCL antibody concentration and isotype were measured using an anticardiolipin ELISA. 50 cases of VTE, CVA and MI along with 149 age-matched controls were recruited from a hospital based case control study. Ages ranged from 15 to 49 years. 1,212 primiparae with uncomplicated pregnancies were recruited from clinics in Kingston and St. Andrew. aCL antibodies were present in 16/50 (32 percent) of CVA, VTE and MI cases and in 23/149 (15.4 percent) of the controls (X = 6.5, p = 0.0107). The estimated relative risk for VTE, CVA and MI associated with aCL antibodies is 2.58 (OR = 2.58; 95 percent CI 1.15-5.77). Among the primiparae 137/807 (16.9 percent) were aCL positive. The impact of aCL antibody presence on pregnancy outcomes has not yet been assessed. aCL antibodies confer a significant risk of VTE, CVA, and MI among women 15-49 years old.(AU)