RESUMO
PURPOSE: This study provides a simple method for improving precision of X-ray computed tomography (CT) scans of irradiated polymer gel dosimetry. The noise affecting CT scans of irradiated gels has been an impediment to the use of clinical CT scanners for gel dosimetry studies. METHODS: In this study, it is shown that multiple scans of a single PAGAT gel dosimeter can be used to extrapolate a "zero-scan" image which displays a similar level of precision to an image obtained by averaging multiple CT images, without the compromised dose measurement resulting from the exposure of the gel to radiation from the CT scanner. RESULTS: When extrapolating the zero-scan image, it is shown that exponential and simple linear fits to the relationship between Hounsfield unit and scan number, for each pixel in the image, provide an accurate indication of gel density. CONCLUSIONS: It is expected that this work will be utilized in the analysis of three-dimensional gel volumes irradiated using complex radiotherapy treatments.
Assuntos
Tomografia Computadorizada por Raios X/métodos , Estudos de Viabilidade , Géis , Processamento de Imagem Assistida por Computador , Polímeros/química , Controle de Qualidade , RadiometriaRESUMO
This study examines the dosimetric accuracy of Gafchromic EBT2 model radiochromic film for use in radiotherapy quality assurance. In this study, film was scanned using an Epson Perfection V700 flatbed scanner in transmission mode at 75 DPI with the subsequent analysis performed using the red and blue colour channels and ImageJ software. Results of this study suggest that the conversion of film optical density to measured dose should, at present, utilise red channel data only, without application of a blue channel correction to the data. For the batch of film examined here, film uniformity and reproducibility appear to have improved compared with published results using older batches. The orientation of the film on the scanner and the side of the film facing the light source were found to have substantial effects on results. Based on the results of this study, it is possible to recommend the use of EBT2 film in routine quality assurance testing for radiotherapy, in situations where a dose uncertainty of up to 2.8% is acceptable.
Assuntos
Dosimetria Fotográfica/instrumentação , Radioterapia/instrumentação , Filme para Raios X/normas , Relação Dose-Resposta à Radiação , Dosimetria Fotográfica/métodos , Dosimetria Fotográfica/normas , Controle de Qualidade , Radioterapia/métodos , Radioterapia/normas , Reprodutibilidade dos TestesRESUMO
In response to the clinical need for a dosimetry system with both high resolution and minimal angular dependence, this study demonstrates the utility of Gafchromic EBT2 radiochromic dosimetry film for the quality assurance of micro-collimated IMRT, RapidArc and TomoTherapy treatments. Firstly, preliminary measurements indicated that the dose response of EBT2 film does not appreciably vary with either the angle of incidence of the radiation beam or the depth in water at which the film is placed. Secondly, prostate treatment plans designed for delivery using static-beam IMRT (collimated using the BrainLab m3 microMLC), RapidArc and TomoTherapy were investigated by comparing dose planes obtained from treatment planning calculations with EBT2 film measurements. For all treatment plans, the proportion of dose points agreeing with the film measurements to within γ (3%,3 mm) was found to be above 95%, with all points agreeing within 5%. The film images provided sufficient information to verify that the treatments could be delivered with an acceptable level of accuracy, while also providing additional information on low-level dose variations that were not predicted by the treatment planning systems. This information included: the location and extent of dose from inter-leaf leakage (in the RapidArc plan) and helical field junctioning (in the TomoTherapy plan), as well as the existence of small regions where the treatment planning system under-predicted the dose from very small treatment segments (in the micro-collimated IMRT plan).
Assuntos
Adenocarcinoma/radioterapia , Neoplasias da Próstata/radioterapia , Radiometria/instrumentação , Planejamento da Radioterapia Assistida por Computador , Radioterapia de Intensidade Modulada , Tomografia Computadorizada por Raios X , Humanos , Masculino , Garantia da Qualidade dos Cuidados de Saúde , Radiometria/métodos , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador/instrumentação , Planejamento da Radioterapia Assistida por Computador/métodos , Radioterapia de Intensidade Modulada/instrumentação , Radioterapia de Intensidade Modulada/métodos , Tomografia Computadorizada por Raios X/instrumentação , Tomografia Computadorizada por Raios X/métodosRESUMO
The purpose of this work is to validate and automate the use of DYNJAWS; a new component module (CM) in the BEAMnrc Monte Carlo (MC) user code. The DYNJAWS CM simulates dynamic wedges and can be used in three modes; dynamic, step-and-shoot and static. The step-and-shoot and dynamic modes require an additional input file defining the positions of the jaw that constitutes the dynamic wedge, at regular intervals during its motion. A method for automating the generation of the input file is presented which will allow for the more efficient use of the DYNJAWS CM. Wedged profiles have been measured and simulated for 6 and 10 MV photons at three field sizes (5 cm × 5 cm, 10 cm × 10 cm and 20 cm × 20 cm), four wedge angles (15°, 30°, 45° and 60°), at d (max) and at 10 cm depth. Results of this study show agreement between the measured and the MC profiles to within 3% of absolute dose or 3 mm distance to agreement for all wedge angles at both energies and depths. The gamma analysis suggests that dynamic mode is more accurate than the step-and-shoot mode. The DYNJAWS CM is an important addition to the BEAMnrc code and will enable the MC verification of patient treatments involving dynamic wedges.
Assuntos
Algoritmos , Modelos Biológicos , Modelos Estatísticos , Método de Monte Carlo , Radiometria/métodos , Planejamento da Radioterapia Assistida por Computador/métodos , Radioterapia Conformacional/métodos , Humanos , Dosagem Radioterapêutica , Sensibilidade e EspecificidadeRESUMO
In this feasibility study an organic plastic scintillator is calibrated against ionisation chamber measurements and then embedded in a polymer gel dosimeter to obtain a quasi-4D radiation detector. This hybrid dosimeter was irradiated with megavoltage x-rays from a linear accelerator, with temporal measurements of the dose rate being acquired by the scintillator and spatial measurements acquired with the gel dosimeter. The detectors employed in this study are radiologically equivalent; and we show that neither detector perturbs the intensity of the radiation field of the other. By employing these detectors in concert, spatial and temporal variations in the radiation intensity can now be detected and gel dosimeters can be calibrated for absolute dose from a single irradiation.
Assuntos
Radiometria , Planejamento da Radioterapia Assistida por Computador/métodos , Contagem de Cintilação/instrumentação , Calibragem , Desenho de Equipamento , Géis/efeitos da radiação , Imageamento Tridimensional , Polímeros/efeitos da radiação , Radiometria/instrumentação , Radiometria/métodos , Dosagem Radioterapêutica , Reprodutibilidade dos Testes , Contagem de Cintilação/métodosRESUMO
Shielded garments are widely recommended for occupational radiation protection in diagnostic and interventional radiology. This study investigated a novel method for efficiently verifying shielded garment integrity while simultaneously acquiring data for lead-equivalence measurements, using two-dimensional topogram images from computed tomography (CT) scanners. This method was tested against more-conventional measurements with superficial and orthovoltage radiotherapy treatment beams, for 12 shielded garments containing 3 different lead-free shielding materials. Despite some energy-dependent results, all shielded garments approximately achieved their specified lead-equivalence for the energy range expected during clinical use for fluoroscopy procedures, except for three shielded skirts that required two layers of material to be overlapped at the front. All lead-equivalence measurements from CT topograms agreed with or conservatively underestimated the kV narrow-beam results. This method is potentially useful for independently assessing the shielding properties of new shielded garments and performing annual checks for damage or degradation of existing shielded garments.
Assuntos
Roupa de Proteção , Proteção Radiológica , Imagens de Fantasmas , Doses de Radiação , Espalhamento de Radiação , Tomografia , Raios XRESUMO
This study investigates and validates the use of the Octavius 4D system for patient specific quality assurance on Halcyon, which is capable of rotating at 4 revolutions per minute (RPM). A commercially available PTW Octavius 4D system was used for this study which had a maximum rotation speed of 3 RPM. Initial validation included testing the accuracy of the inclinometer, percent depth doses (PDD), output factors, and dose profiles for selected static square fields. The same static fields were also subject to a gamma comparison with the TPS. This was followed by an evaluation of twelve clinical treatment plans and seven non-clinical plans with varying gantry rotation speeds. All testing was completed using detector array measurement times of 200 ms and 100 ms. Inclinometer accuracy was within 0.3° of actual gantry angle. Output factors varied less than 0.6%, PDD differences were no greater than 1.4%, and dose profile differences were less than 2.2%. Gamma pass rates for the static fields were 96.7% (2%/2mm) and 99.7% (3%/3mm). A prototype control unit, which had a maximum rotation speed of 4 RPM was also used to test the clinical and non-clinical plans. For the clinical plans, the mean gamma pass rates (2%/2mm) were 86.1% and 88.1% for the commercial unit and prototype unit respectively. Results using a measurement time of 200 ms were superior to those using 100 ms. For Halcyon deliveries greater than 3 RPM, worst case gamma results for the commercial unit were 28.6% compared to 98.5% using the prototype unit. Accurate patient specific quality assurance results can be obtained using the Octavius 4D system with a Halcyon linac, provided that the system measurement time is kept at 200 ms and the rotation speed of Halycon does not exceed 3 RPM. For higher RPM deliveries, an Octavius 4D unit with 4 RPM rotation capability is recommended.
Assuntos
Radioterapia de Intensidade Modulada , Humanos , Aceleradores de Partículas , Imagens de Fantasmas , Planejamento da Radioterapia Assistida por Computador , RotaçãoRESUMO
Given the existing literature on the subject, there is obviously a need for specific advice on quality assurance (QA) tolerances for departments using or implementing 3D printed bolus for radiotherapy treatments. With a view to providing initial suggested QA tolerances for 3D printed bolus, this study evaluated the dosimetric effects of changes in bolus geometry and density, for a particularly common and challenging clinical situation: specifically, volumetric modulated arc therapy (VMAT) treatment of the nose. Film-based dose verification measurements demonstrated that both the AAA and the AXB algorithms used by the Varian Eclipse treatment planning system (Varian Medical Systems, Palo Alto, USA) were capable of providing sufficiently accurate dose calculations to allow this planning system to be used to evaluate the effects of bolus errors on dose distributions from VMAT treatments of the nose. Thereafter, the AAA and AXB algorithms were used to calculate the dosimetric effects of applying a range of simulated errors to the design of a virtual bolus, to identify QA tolerances that could be used to avoid clinically significant effects from common printing errors. Results were generally consistent, whether the treatment target was superficial and treated with counter-rotating coplanar arcs or more-penetrating and treated with noncoplanar arcs, and whether the dose was calculated using the AAA algorithm or the AXB algorithm. The results of this study suggest the following QA tolerances are advisable, when 3D printed bolus is fabricated for use in photon VMAT treatments of the nose: bolus relative electron density variation within [Formula: see text] (although an action level at [Formula: see text] may be permissible); bolus thickness variation within [Formula: see text] mm (or 0.5 mm variation on opposite sides); and air gap between bolus and skin [Formula: see text] mm. These tolerances should be investigated for validity with respect to other treatment modalities and anatomical sites. This study provides a set of baselines for future comparisons and a useful method for identifying additional or alternative 3D printed bolus QA tolerances.
Assuntos
Planejamento da Radioterapia Assistida por Computador , Radioterapia de Intensidade Modulada , Imagens de Fantasmas , Impressão Tridimensional , Dosagem RadioterapêuticaRESUMO
PURPOSE: The component modules in the standard BEAMnrc istribution may appear to be insufficient to model micro-multileaf collimators that have trifaceted leaf ends and complex leaf profiles. This note indicates, however, that accurate Monte Carlo simulations of radiotherapy beams defined by a complex collimation device can be completed using BEAMnrc's standard VARMLC component module. METHODS: That this simple collimator model can produce spatially and dosimetrically accurate microcollimated fields is illustrated using comparisons with ion chamber and film measurements of the dose deposited by square and irregular fields incident on planar, homogeneous water phantoms. RESULTS: Monte Carlo dose calculations for on-axis and off-axis fields are shown to produce good agreement with experimental values, even on close examination of the penumbrae. CONCLUSIONS: The use of a VARMLC model of the micro-multileaf collimator, along with a commissioned model of the associated linear accelerator, is therefore recommended as an alternative to the development or use of in-house or third-party component modules for simulating stereotactic radiotherapy and radiosurgery treatments. Simulation parameters for the VARMLC model are provided which should allow other researchers to adapt and use this model to study clinical stereotactic radiotherapy treatments.
Assuntos
Dosimetria Fotográfica/métodos , Algoritmos , Simulação por Computador , Desenho de Equipamento , Humanos , Método de Monte Carlo , Aceleradores de Partículas , Imagens de Fantasmas , Doses de Radiação , Radiocirurgia/métodos , Planejamento da Radioterapia Assistida por Computador/instrumentação , Reprodutibilidade dos Testes , Software , Água/químicaRESUMO
In this study, a method was developed for delivering high dose rate (HDR) brachytherapy treatments to basal cell carcinomas (BCCs) as well as squamous cell carcinomas (SCCs) of the lower eyelid via superficial catheters. Clinically-realistic BCC/SCC treatment areas were marked in the lower-eyelid region on a head phantom and several arrangements of catheters and bolus were trialled for treating those areas. The use of one or two catheters of different types was evaluated, and sources of dosimetric uncertainty (including air gaps) were evaluated and mitigated. Test treatments were planned for delivery with an iridium-192 source, using the Oncentra Brachy treatment planning system (Elekta AB, Stockholm, Sweden). Dose distributions were evaluated using radiochromic film. The proposed method was shown to be clinically viable, for using superficial HDR brachytherapy to overcome anatomical difficulties and create non-surgical treatments for BCC and SCC of the lower eyelid.
Assuntos
Braquiterapia , Neoplasias Palpebrais , Neoplasias Palpebrais/radioterapia , Pálpebras , Humanos , Radiometria , Dosagem RadioterapêuticaRESUMO
The increase in complexity of treatment plans over time through modalities such as intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) has often not been met with an increase in capability of the secondary dose calculation checking systems typically used to verify the treatment planning system. Monte Carlo (MC) codes such as EGSnrc have become easily available and are capable of performing calculations of highly complex radiotherapy treatments. This educational note demonstrates a method for implementing and using a fully automated system for performing and analysing full MC calculations of conformal, IMRT and VMAT radiotherapy plans. Example calculations were based on BEAMnrc/DOSXYZnrc and are performed automatically after either uploading exported plan DICOM data through a Python-based web interface, or exporting DICOM data to a monitored network location. This note demonstrates how completed MC calculations can then be analysed using an automatically generated dose point comparison report, or easily re-imported back into the treatment planning system. Agreement between the TPS and MC calculation was an improvement on agreement between RadCalc and the TPS, with differences ranging from 1.2 to 5.5% between RadCalc and the treatment planning system (TPS), and 0.1-1.7% between MC and TPS. Comparison of the dose-volume histogram (DVH) parameters [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text] for the example VMAT plans showed agreement for the mean planning target volume dose within [Formula: see text], [Formula: see text] and [Formula: see text] generally within [Formula: see text] with the exception of a brain case, and [Formula: see text] within [Formula: see text]. Overall, this note provides a demonstration of a system that has been integrated well into existing clinical workflow, and has been shown to be a valuable additional tool in the secondary checking of treatment plan calculations.
Assuntos
Método de Monte Carlo , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador , Simulação por Computador , Relação Dose-Resposta à Radiação , Humanos , Radioterapia Conformacional , Radioterapia de Intensidade Modulada , Interface Usuário-ComputadorRESUMO
Bolus plays an important role in the radiation therapy of superficial lesions and the application of 3D printing to its design can improve fit and dosimetry. This study quantitatively compares the fits of boluses designed from different imaging modalities. A head phantom was imaged using three systems: a CT simulator, a 3D optical scanner, and an interchangeable lens camera. Nose boluses were designed and 3D printed from each modality. A 3D printed phantom with air gaps of known thicknesses was used to calibrate mean HU to measure air gaps of unknown thickness and assess the fit of each bolus on the head phantom. The bolus created from the optical scanner data resulted in the best fit, with a mean air gap of 0.16 mm. Smoothing of the CT bolus resulted in a more clinically suitable model, comparable to that from the optical scanner method. The bolus produced from the photogrammetry method resulted in air gaps larger than 1 mm in thickness. The use of optical scanner and photogrammetry models have many advantages over the conventional bolus-from-CT method, however workflow should be refined to ensure accuracy if implemented clinically.
Assuntos
Óptica e Fotônica/instrumentação , Fotogrametria , Impressão Tridimensional , Tomografia Computadorizada por Raios X , Ar , Calibragem , Imagens de FantasmasRESUMO
3D printing is a promising solution for the production of bespoke phantoms and phantom components, for radiotherapy dosimetry and quality assurance (QA) purposes. This proof-of-concept study investigated the use of a dual-head printer to deposit two different filaments (polylactic acid (PLA) and StoneFil PLA-concrete (Formfutura BV, Nijmegen, Netherlands)) at several different in-fill densities, to achieve quasi-simultaneous 3D printing of muscle-, lung- and bone-equivalent media. A Raise 3D Pro 3D printer (Raise 3D Technologies Inc, Irvine, USA) was used to print one thoracic and one cranial phantom slab. Analysis using in-house 3D print QA software showed that the two humanoid phantom slabs geometrically matched the stereolithography (STL) files on which they were based, within 0.3 mm, except in one area of the thoracic slab that was affected by thermal warping by up to 3.4 mm. The 3D printed muscle, lung and bone materials in the two humanoid phantom slabs were approximately radiologically-equivalent to human muscle, lung and bone. In particular, the use of StoneFil with a nominally constant in-fill density of 100% resulted in regions that were approximately inner-bone-equivalent, at kV and MV energies. These regions were bounded by walls that were substantially denser than inner bone, although generally not dense enough to be truly cortical-bone-equivalent. This proof-of-concept study demonstrated a method by which multiple tissue-equivalent materials (eg. muscle-, lung- and bone-equivalent media) can be deposited within one 3D print, allowing complex phantom components to be fabricated efficiently in a clinical setting.
Assuntos
Osso e Ossos/diagnóstico por imagem , Pulmão/diagnóstico por imagem , Músculos/diagnóstico por imagem , Impressão Tridimensional , Estudo de Prova de Conceito , Humanos , Imagens de Fantasmas , Tomografia Computadorizada por Raios XRESUMO
The effects of radiation backscattered from the secondary collimators into the monitor chamber in an Elekta linac (producing 6 and 10 MV photon beams) are investigated using BEAMnrc Monte Carlo simulations. The degree and effects of this backscattered radiation are assessed by evaluating the changes to the calculated dose in the monitor chamber, and by determining a correction factor for those changes. Additionally, the fluence and energy characteristics of particles entering the monitor chamber from the downstream direction are evaluated by examining BEAMnrc phase-space data. It is shown that the proportion of particles backscattered into the monitor chamber is small (< 0.35%), for all field sizes studied. However, when the backscatter plate is removed from the model linac, these backscattered particles generate a noticeable increase in dose to the monitor chamber (up to approximately 2.4% for the 6 MV beam and up to 4.4% for the 10 MV beam). With its backscatter plate in place, the Elekta linac (operating at 6 and 10 MV) is subject to negligible variation of monitor chamber dose with field size. At these energies, output variations in photon beams produced by the clinical Elekta linear accelerator can be attributed to head scatter alone. Corrections for field-size-dependence of monitor chamber dose are not necessary when running Monte Carlo simulations of the Elekta linac operating at 6 and 10 MV.
Assuntos
Método de Monte Carlo , Aceleradores de Partículas/instrumentação , Radioterapia/instrumentação , Simulação por Computador , Radioterapia/métodos , Dosagem RadioterapêuticaRESUMO
The advantages, in terms of heart dose sparing, resulting from using a breath-hold technique when treating supine left breast radiotherapy patients are widely accepted, and increasing numbers of radiotherapy departments are implementing breath-hold techniques. However, due to differences in patient setup and treatment planning protocols between radiotherapy departments, it is important to assess the benefits of using a breath-hold technique within each department, before or during implementation. This study investigated the use of retrospective analysis of past patient treatment plans, as a means to identify the potential for breath-hold techniques to benefit patients. In-house "Treatment and Dose Assessor" code was used to complete a bulk retrospective evaluation of dose-volume metrics for 708 supine and 13 prone breast and chest wall radiotherapy treatments, that were planned using the same clinical protocols, which did not utilise a breath hold technique. For supine patients, results showed statistically significant differences between heart doses from left and right breast treatment plans, in the absence of significant differences between lung doses from left and right breast treatment plans, confirming the potential benefit of using a breath-hold technique for supine left breast radiotherapy patients. Fewer than 1% of the right breast treatment plans showed heart doses high enough to suggest a possible benefit from using a breath-hold technique. Approximately 50% of the prone left breast treatment plans included very low heart doses without intervention, and may therefore have shown no noticeable dosimetric benefit from the use of a breath hold. This study demonstrated the extent of information that can be obtained using retrospective data analysis, before or instead of obtaining multiple CT images of patients and completing a process of dual planning and prospective dose evaluation.
Assuntos
Neoplasias da Mama/radioterapia , Suspensão da Respiração , Análise de Dados , Relação Dose-Resposta à Radiação , Feminino , Coração/efeitos da radiação , Humanos , Pulmão/efeitos da radiação , Planejamento da Radioterapia Assistida por Computador , Estudos RetrospectivosRESUMO
A gel dosimeter has been developed utilising a recently reported system for reducing Fe3+ diffusion in a Fricke gel dosimeter which chelates xylenol orange to the gelling agent poly(vinyl alcohol) (PVA). Formulations were investigated using both gelatin and PVA as the gelling agent, along with the inclusion of glyoxal. The resulting gel had an optical density dose response of 0.0031 Gy-1, an auto-oxidation rate of 0.000 23 h-1, and a diffusion rate of 0.132 mm2 h-1 which is a significant improvement over previously reported gelatin based Fricke gel dosimeters. The gel was also shown to be energy and dose-rate independent and could be reused after irradiation. Thus, this gel dosimeter has the potential to provide a safe and practical solution to three dimensional radiation dosimetry in the medical environment.
Assuntos
Géis/química , Dosímetros de Radiação/normas , Difusão , Géis/efeitos da radiação , Fenóis/química , Álcool de Polivinil/química , Radiometria/instrumentação , Radiometria/métodos , Sulfóxidos/químicaRESUMO
This work validates the use of an amorphous-silicon, flat-panel electronic portal imaging device (a-Si EPID) for use as a gauge of patient or phantom radiological thickness, as an alternative to dosimetry. The response of the a-Si EPID is calibrated by adapting a technique previously applied to scanning liquid ion chamber EPIDs, and the stability, accuracy and reliability of this calibration are explored in detail. We find that the stability of this calibration, between different linacs at the same centre, is sufficient to justify calibrating only one of the EPIDs every month and using the calibration data thus obtained to perform measurements on all of the other linacs. Radiological thickness is shown to provide a reliable means of relating experimental measurements to the results of BEAMnrc Monte Carlo simulations of the linac-phantom-EPID system. For these reasons we suggest that radiological thickness can be used to verify radiotherapy treatment delivery and identify changes in the treatment field, patient position and target location, as well as patient physical thickness.
Assuntos
Diagnóstico por Imagem/métodos , Eletrônica Médica/métodos , Método de Monte Carlo , Radioterapia/métodos , Silício/química , Calibragem , Cabeça , Imagens de Fantasmas , Sensibilidade e EspecificidadeRESUMO
Gafchromic EBT3 film is widely used for patient specific quality assurance of complex treatment plans. Film dosimetry techniques commonly involve the use of transmission scanning to produce TIFF files, which are analysed using a non-linear calibration relationship between the dose and red channel net optical density (netOD). Numerous film calibration techniques featured in the literature have not been independently verified or evaluated. A range of previously published film dosimetry techniques were re-evaluated, to identify whether these methods produce better results than the commonly-used non-linear, netOD method. EBT3 film was irradiated at calibration doses between 0 and 4000 cGy and 25 pieces of film were irradiated at 200 cGy to evaluate uniformity. The film was scanned using two different scanners: The Epson Perfection V800 and the Epson Expression 10000XL. Calibration curves, uncertainty in the fit of the curve, overall uncertainty and uniformity were calculated following the methods described by the different calibration techniques. It was found that protocols based on a conventional film dosimetry technique produced results that were accurate and uniform to within 1%, while some of the unconventional techniques produced much higher uncertainties (> 25% for some techniques). Some of the uncommon methods produced reliable results when irradiated to the standard treatment doses (< 400 cGy), however none could be recommended as an efficient or accurate replacement for a common film analysis technique which uses transmission scanning, red colour channel analysis, netOD and a non-linear calibration curve for measuring doses up to 4000 cGy when using EBT3 film.
Assuntos
Dosimetria Fotográfica/instrumentação , Dosimetria Fotográfica/métodos , Calibragem , Relação Dose-Resposta à Radiação , Dinâmica não Linear , IncertezaRESUMO
This study evaluated the feasibility of combining the 'zero-scan' (ZS) X-ray computed tomography (CT) based polymer gel dosimeter (PGD) readout with adaptive mean (AM) filtering for improving the signal to noise ratio (SNR), and to compare these results with available average scan (AS) X-ray CT readout techniques. NIPAM PGD were manufactured, irradiated with 6 MV photons, CT imaged and processed in Matlab. AM filter for two iterations, with 3 × 3 and 5 × 5 pixels (kernel size), was used in two scenarios (a) the CT images were subjected to AM filtering (pre-processing) and these were further employed to generate AS and ZS gel images, and (b) the AS and ZS images were first reconstructed from the CT images and then AM filtering was carried out (post-processing). SNR was computed in an ROI of 30 × 30 for different pre and post processing cases. Results showed that the ZS technique combined with AM filtering resulted in improved SNR. Using the previously-recommended 25 images for reconstruction the ZS pre-processed protocol can give an increase of 44% and 80% in SNR for 3 × 3 and 5 × 5 kernel sizes respectively. However, post processing using both techniques and filter sizes introduced blur and a reduction in the spatial resolution. Based on this work, it is possible to recommend that the ZS method may be combined with pre-processed AM filtering using appropriate kernel size, to produce a large increase in the SNR of the reconstructed PGD images.
Assuntos
Algoritmos , Géis/química , Processamento de Imagem Assistida por Computador/normas , Polímeros/química , Dosímetros de Radiação/normas , Tomografia Computadorizada por Raios X/normas , Humanos , Padrões de Referência , Razão Sinal-RuídoRESUMO
Although the participation of women within the science, technology, engineering and mathematics workforces has been widely discussed over recent decades, the recording and analysis of data pertaining to the gender balance of medical physicists in Australia and New Zealand remains rare. This study aimed to provide a baseline for evaluating future changes in workforce demographics by quantifying the current level of representation of women in the Australasian medical physics workforce and providing an indication of the relative contribution made by those women to the local research environment. The 2015 Australasian College of Physical Scientists and Engineers in Medicine (ACPSEM) member directory and list of chief physicists at ACPSEM-accredited radiation oncology and diagnostic imaging training centres were interrogated to identify the gender balance of medical physicists working in Australia and New Zealand. A specific investigation of the employment levels of all medical physicists in Queensland was undertaken to provide an example of the gender balance at different levels of seniority in one large Australian state. Lists of authors of medical physics presentations at ACPSEM annual conferences and authors of publications in the ACPSEM's official journal, were used to provide an indication of the gender balance in published research within Australia and New Zealand. The results of this study showed that women currently constitute approximately 28 % of the medical physics workforce in Australia and New Zealand, distributed disproportionally in junior roles; there is a decrease in female participation in the field with increasing levels of seniority, which is particularly apparent in the stratified data obtained for the Queensland workforce. Comparisons with older data suggest that this situation has changed little since 2008. Examination of ACPSEM conference presentations suggested that there are similar disparities between the gender-balance of proffered and invited or keynote speakers (28 % and 13 % from female authors) and the gender balance of certified and chief physicists (28 % and 21 % female). The representation of women in the ACPSEM journal does not differ substantially between authorship of proffered versus invited work (22 % and 19 % from female authors). While this work was limited to evaluating the membership, annual conference and official journal of the ACPSEM (rather than evaluating the entire medical physics workforce and the contributions of male and female physicists to international conferences and publications), this study nonetheless led to the following recommendations: that a longitudinal study analysing correlations between age, period of service, seniority and gender should be undertaken and that future ACPSEM workforce surveys should include analyses of gender representation.