Detalhe da pesquisa
1.
Dephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks.
Mol Cell
; 54(3): 512-25, 2014 May 08.
Artigo
Inglês
| MEDLINE | ID: mdl-24703952
2.
Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion.
J Med Chem
; 64(8): 4430-4449, 2021 04 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33829783
3.
MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage.
Cancer Cell
; 39(2): 209-224.e11, 2021 02 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33450196
4.
Nuclear matrix binding site in the Rad51 recombinase.
J Cell Physiol
; 219(1): 202-8, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19097142
5.
The complexity of double-strand break ends is a factor in the repair pathway choice.
Radiat Res
; 171(4): 397-404, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19397440
6.
Publisher Correction: p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.
Nat Med
; 30(5): 1506, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38332041
7.
EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma.
Cancer Cell
; 33(2): 202-216.e6, 2018 02 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29358035
8.
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.
Nat Med
; 22(8): 861-8, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27376578
9.
Emerging role of protein phosphatases changes the landscape of phospho-signaling in DNA damage response.
DNA Repair (Amst)
; 32: 58-65, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-25956864
10.
p16INK4a impairs homologous recombination-mediated DNA repair in human papillomavirus-positive head and neck tumors.
Cancer Res
; 74(6): 1739-51, 2014 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24473065
11.
The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Nat Cell Biol
; 15(10): 1220-30, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-24056301
12.
Loss of PPP2R2A inhibits homologous recombination DNA repair and predicts tumor sensitivity to PARP inhibition.
Cancer Res
; 72(24): 6414-24, 2012 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23087057
13.
Protein phosphatase 2A as a potential target for anticancer therapy.
Anticancer Agents Med Chem
; 11(1): 38-46, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-21288198