Detalhe da pesquisa
1.
Functional analysis of cell lines derived from SMAD3-related Loeys-Dietz syndrome patients provides insights into genotype-phenotype relation.
Hum Mol Genet
; 33(12): 1090-1104, 2024 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38538566
2.
DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces.
Nucleic Acids Res
; 2024 Jun 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38828772
3.
DNA repair by the MRN complex: break it to make it.
Cell
; 135(1): 14-6, 2008 Oct 03.
Artigo
Inglês
| MEDLINE | ID: mdl-18854148
4.
Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner.
PLoS Genet
; 16(1): e1008550, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31945059
5.
HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair.
Nucleic Acids Res
; 48(5): 2442-2456, 2020 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-31960047
6.
Mismatch repair inhibits homeologous recombination via coordinated directional unwinding of trapped DNA structures.
Mol Cell
; 51(3): 326-37, 2013 Aug 08.
Artigo
Inglês
| MEDLINE | ID: mdl-23932715
7.
The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair.
Nucleic Acids Res
; 47(22): 11667-11680, 2019 12 16.
Artigo
Inglês
| MEDLINE | ID: mdl-31598722
8.
Genome editing by natural and engineered CRISPR-associated nucleases.
Nat Chem Biol
; 14(7): 642-651, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29915237
9.
Comparison of High- and Low-LET Radiation-Induced DNA Double-Strand Break Processing in Living Cells.
Int J Mol Sci
; 21(18)2020 Sep 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32917044
10.
Ex vivo treatment of prostate tumor tissue recapitulates in vivo therapy response.
Prostate
; 79(4): 390-402, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30520109
11.
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.
Mol Cell
; 41(5): 529-42, 2011 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-21362549
12.
Architectural plasticity of human BRCA2-RAD51 complexes in DNA break repair.
Nucleic Acids Res
; 45(8): 4507-4518, 2017 05 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28168276
13.
Heat-induced BRCA2 degradation in human tumours provides rationale for hyperthermia-PARP-inhibitor combination therapies.
Int J Hyperthermia
; 34(4): 407-414, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28705099
14.
Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair.
Nucleic Acids Res
; 44(14): 6770-86, 2016 08 19.
Artigo
Inglês
| MEDLINE | ID: mdl-27174933
15.
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.
Mol Cell
; 35(1): 116-27, 2009 Jul 10.
Artigo
Inglês
| MEDLINE | ID: mdl-19595721
16.
Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair.
Int J Cancer
; 139(2): 467-79, 2016 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26933761
17.
Tumor slice culture system to assess drug response of primary breast cancer.
BMC Cancer
; 16: 78, 2016 Feb 09.
Artigo
Inglês
| MEDLINE | ID: mdl-26860465
18.
Hallmarks of hyperthermia in driving the future of clinical hyperthermia as targeted therapy: translation into clinical application.
Int J Hyperthermia
; 32(1): 89-95, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-26803991
19.
Improving efficacy of hyperthermia in oncology by exploiting biological mechanisms.
Int J Hyperthermia
; 32(4): 446-54, 2016 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27086587
20.
From DNA end chemistry to cell-cycle response: the importance of structure, even when it's broken.
Mol Cell
; 30(1): 5-6, 2008 Apr 11.
Artigo
Inglês
| MEDLINE | ID: mdl-18406321