Detalhe da pesquisa
1.
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.
Cell
; 169(2): 258-272.e17, 2017 Apr 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28388410
2.
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.
Cell
; 158(5): 1094-1109, 2014 Aug 28.
Artigo
Inglês
| MEDLINE | ID: mdl-25171410
3.
Dietary modifications for enhanced cancer therapy.
Nature
; 579(7800): 507-517, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32214253
4.
Regulatory mechanisms of one-carbon metabolism enzymes.
J Biol Chem
; 299(12): 105457, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37949226
5.
FDX1 regulates cellular protein lipoylation through direct binding to LIAS.
J Biol Chem
; 299(9): 105046, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37453661
6.
Simultaneous isolation of hormone receptor-positive breast cancer organoids and fibroblasts reveals stroma-mediated resistance mechanisms.
J Biol Chem
; 299(8): 105021, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37423299
7.
Histidine catabolism is a major determinant of methotrexate sensitivity.
Nature
; 559(7715): 632-636, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29995852
8.
The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase.
J Biol Chem
; 298(2): 101531, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34953855
9.
Author Correction: Histidine catabolism is a major determinant of methotrexate sensitivity.
Nature
; 602(7895): E17-E18, 2022 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-35017686
10.
Potential Benefits and Pitfalls of Histidine Supplementation for Cancer Therapy Enhancement.
J Nutr
; 150(Suppl 1): 2580S-2587S, 2020 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33000153
11.
mTOR generates an auto-amplification loop by triggering the ßTrCP- and CK1α-dependent degradation of DEPTOR.
Mol Cell
; 44(2): 317-24, 2011 Oct 21.
Artigo
Inglês
| MEDLINE | ID: mdl-22017877
12.
Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF{beta}-TrCP by single substrate depletion.
Genes Dev
; 24(5): 470-7, 2010 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20194439
13.
Critical role for IL-1ß in DNA damage-induced mucositis.
Proc Natl Acad Sci U S A
; 111(6): E702-11, 2014 Feb 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24469832
14.
Regulation of NF-κB by ubiquitination and degradation of the IκBs.
Immunol Rev
; 246(1): 77-94, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22435548
15.
Optimized Mass Spectrometry Detection of Thyroid Hormones and Polar Metabolites in Rodent Cerebrospinal Fluid.
Metabolites
; 14(2)2024 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38392972
16.
Folate depletion induces erythroid differentiation through perturbation of de novo purine synthesis.
Sci Adv
; 10(5): eadj9479, 2024 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38295180
17.
Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy.
bioRxiv
; 2024 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38405985
18.
Notes from the 2022 Folate, Vitamin B12, and One-Carbon Metabolism Conference.
Metabolites
; 13(4)2023 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37110145
19.
Correction: Maynard et al. Notes from the 2022 Folate, Vitamin B12, and One-Carbon Metabolism Conference. Metabolites 2023, 13, 486.
Metabolites
; 13(6)2023 Jun 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37367931
20.
Optimized Mass Spectrometry Detection of Thyroid Hormones and Polar Metabolites in Rodent Cerebrospinal Fluid.
bioRxiv
; 2023 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-38116027