Detalhe da pesquisa
1.
Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature
; 570(7761): E53, 2019 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-31142845
2.
Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature
; 564(7736): 439-443, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30405246
3.
RIP3 induces apoptosis independent of pronecrotic kinase activity.
Mol Cell
; 56(4): 481-95, 2014 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25459880
4.
Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.
J Immunol
; 192(12): 5476-80, 2014 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24821972
5.
Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology.
J Biol Chem
; 285(22): 17054-64, 2010 May 28.
Artigo
Inglês
| MEDLINE | ID: mdl-20356837
6.
Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor.
ACS Med Chem Lett
; 10(5): 780-785, 2019 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31097999
7.
Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer.
ACS Med Chem Lett
; 10(6): 857-862, 2019 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31223438
8.
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.
J Med Chem
; 60(4): 1247-1261, 2017 02 23.
Artigo
Inglês
| MEDLINE | ID: mdl-28151659
9.
DNA-Encoded Library Screening Identifies Benzo[b][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors.
J Med Chem
; 59(5): 2163-78, 2016 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26854747
10.
MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses.
PLoS One
; 10(5): e0127083, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25965667
11.
Targeted overexpression of androgen receptor in osteoblasts: unexpected complex bone phenotype in growing animals.
Endocrinology
; 145(7): 3507-22, 2004 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-15131013
12.
Identification of selective small molecule inhibitors of the nucleotide-binding oligomerization domain 1 (NOD1) signaling pathway.
PLoS One
; 9(5): e96737, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24806487
13.
Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway.
PLoS One
; 8(8): e69619, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23936340
14.
Bone morphogenetic protein type IA receptor signaling regulates postnatal osteoblast function and bone remodeling.
J Biol Chem
; 279(26): 27560-6, 2004 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-15090551