Detalhe da pesquisa
1.
Remodeling oncogenic transcriptomes by small molecules targeting NONO.
Nat Chem Biol
; 19(7): 825-836, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36864190
2.
Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments.
Bioorg Med Chem Lett
; 29(1): 36-39, 2019 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30455147
3.
A masked zinger to block GPX4.
Nat Chem Biol
; 16(5): 482-483, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32231342
4.
A Small Molecule That Switches a Ubiquitin Ligase From a Processive to a Distributive Enzymatic Mechanism.
J Am Chem Soc
; 137(39): 12442-5, 2015 Oct 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26371805
5.
Blockade of the Lysophosphatidylserine Lipase ABHD12 Potentiates Ferroptosis in Cancer Cells.
ACS Chem Biol
; 15(4): 871-877, 2020 04 17.
Artigo
Inglês
| MEDLINE | ID: mdl-32195565
6.
Covalent-Fragment Screening of BRD4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites.
ACS Chem Biol
; 15(4): 1036-1049, 2020 04 17.
Artigo
Inglês
| MEDLINE | ID: mdl-32149490
7.
Methodology for Identification of Cysteine-Reactive Covalent Inhibitors.
Methods Mol Biol
; 1967: 245-262, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31069775
8.
Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.
ChemMedChem
; 13(19): 2014-2023, 2018 10 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30028574
9.
Covalent Tethering of Fragments For Covalent Probe Discovery.
Medchemcomm
; 7(4): 576-585, 2016 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27398190
10.
A fragment-based method to discover irreversible covalent inhibitors of cysteine proteases.
J Med Chem
; 57(11): 4969-74, 2014 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-24870364