Detalhe da pesquisa
1.
KCC2 is required for the survival of mature neurons but not for their development.
J Biol Chem
; 296: 100364, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33539918
2.
KCC2 activity is critical in limiting the onset and severity of status epilepticus.
Proc Natl Acad Sci U S A
; 112(11): 3523-8, 2015 Mar 17.
Artigo
Inglês
| MEDLINE | ID: mdl-25733865
3.
Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo.
J Neurosci
; 35(21): 8291-6, 2015 May 27.
Artigo
Inglês
| MEDLINE | ID: mdl-26019342
4.
Discovery of the Migraine Prevention Therapeutic Aimovig (Erenumab), the First FDA-Approved Antibody against a G-Protein-Coupled Receptor.
ACS Pharmacol Transl Sci
; 2(6): 485-490, 2019 Dec 13.
Artigo
Inglês
| MEDLINE | ID: mdl-32259079
5.
Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy.
EBioMedicine
; 32: 62-71, 2018 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-29884458
6.
Seizing Control of KCC2: A New Therapeutic Target for Epilepsy.
Trends Neurosci
; 40(9): 555-571, 2017 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28803659
7.
Expandable and Rapidly Differentiating Human Induced Neural Stem Cell Lines for Multiple Tissue Engineering Applications.
Stem Cell Reports
; 7(3): 557-570, 2016 09 13.
Artigo
Inglês
| MEDLINE | ID: mdl-27569063