Detalhe da pesquisa
1.
Proteomic profiling of murine biliary-derived hepatic organoids and their capacity for drug disposition, bioactivation and detoxification.
Arch Toxicol
; 95(7): 2413-2430, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34050779
2.
Dapsone- and nitroso dapsone-specific activation of T cells from hypersensitive patients expressing the risk allele HLA-B*13:01.
Allergy
; 74(8): 1533-1548, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30844087
3.
Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile.
Arch Toxicol
; 91(1): 439-452, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-27039104
4.
The potential of cytokines as safety biomarkers for drug-induced liver injury.
Eur J Clin Pharmacol
; 66(10): 961-76, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20694460
5.
Investigation of the immunogenicity of p-phenylenediamine and Bandrowski's base in the mouse.
Toxicol Lett
; 185(3): 153-9, 2009 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-19136049
6.
The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity.
Toxicol In Vitro
; 53: 136-147, 2018 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-30096366
7.
Kinetic characterization of bile salt transport by human NTCP (SLC10A1).
Toxicol In Vitro
; 46: 189-193, 2018 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-29024779
8.
From the Cover: Characterization of Isoniazid-Specific T-Cell Clones in Patients with anti-Tuberculosis Drug-Related Liver and Skin Injury.
Toxicol Sci
; 155(2): 420-431, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27803386
9.
Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
Toxicol Sci
; 154(2): 416-429, 2016 12.
Artigo
Inglês
| MEDLINE | ID: mdl-27637899
10.
Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy.
Sci Rep
; 5: 13601, 2015 Sep 02.
Artigo
Inglês
| MEDLINE | ID: mdl-26329825
11.
Hepatocellular bioactivation and cytotoxicity of the synthetic endoperoxide antimalarial arteflene.
Chem Biol Interact
; 147(2): 173-84, 2004 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15013819
12.
The genotoxic potential of methapyrilene using the alkaline Comet assay in vitro and in vivo.
Toxicology
; 290(2-3): 249-57, 2011 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-22015589
13.
Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster.
Pharmacogenet Genomics
; 16(4): 287-96, 2006 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-16538175
14.
Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase.
Hepatology
; 32(2): 321-33, 2000 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-10915739