Detalhe da pesquisa
1.
Semi-mechanistic population pharmacokinetic/pharmacodynamic modeling of a Plasmodium elongation factor 2 inhibitor cabamiquine for prevention and cure of malaria.
Antimicrob Agents Chemother
; 67(12): e0089123, 2023 12 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37966273
2.
Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside.
Malar J
; 21(1): 151, 2022 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35570264
3.
COVID-19 infection in patients with haematological disease - A tertiary centre experience from north India.
Indian J Med Res
; 155(5&6): 570-574, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35975348
4.
Population pharmacokinetic model selection assisted by machine learning.
J Pharmacokinet Pharmacodyn
; 49(2): 257-270, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34708337
5.
Fast screening of covariates in population models empowered by machine learning.
J Pharmacokinet Pharmacodyn
; 48(4): 597-609, 2021 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-34019213
6.
Tumor growth inhibition modeling in patients with second line biliary tract cancer and first line non-small cell lung cancer based on bintrafusp alfa trials.
CPT Pharmacometrics Syst Pharmacol
; 13(1): 143-153, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38087967
7.
Immunogenicity of avelumab in patients with metastatic Merkel cell carcinoma or advanced urothelial carcinoma.
Clin Transl Sci
; 17(3): e13730, 2024 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38411318
8.
Variable or variate? A conundrum in pharmacometrics exposure-response models.
CPT Pharmacometrics Syst Pharmacol
; 12(2): 144-147, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36537836
9.
Nontubercular bacterial and fungal infections in patients of chronic obstructive pulmonary disease.
Ann Afr Med
; 22(1): 77-81, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36695226
10.
A multistate modeling and simulation framework to learn dose-response of oncology drugs: Application to bintrafusp alfa in non-small cell lung cancer.
CPT Pharmacometrics Syst Pharmacol
; 12(11): 1738-1750, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37165943
11.
Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands.
Lancet Infect Dis
; 23(10): 1164-1174, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37414066
12.
A semimechanistic pharmacokinetic-enzyme turnover model for rifampin autoinduction in adult tuberculosis patients.
Antimicrob Agents Chemother
; 56(4): 2091-8, 2012 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-22252827
13.
Avelumab Dose Selection for Clinical Studies in Pediatric Patients with Solid Tumors.
Clin Pharmacokinet
; 61(7): 985-995, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35484319
14.
Model-informed drug development supporting the approval of the avelumab flat-dose regimen in patients with advanced renal cell carcinoma.
CPT Pharmacometrics Syst Pharmacol
; 11(4): 458-468, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35166465
15.
Applying Modeling and Simulations for Rational Dose Selection of Novel Toll-Like Receptor 7/8 Inhibitor Enpatoran for Indications of High Medical Need.
Clin Pharmacol Ther
; 112(2): 297-306, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35390178
16.
Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avelumab.
Clin Cancer Res
; 28(7): 1363-1371, 2022 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34921021
17.
Model-informed approach for risk management of bleeding toxicities for bintrafusp alfa, a bifunctional fusion protein targeting TGF-ß and PD-L1.
Cancer Chemother Pharmacol
; 90(4): 369-379, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36066618
18.
Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab.
CPT Pharmacometrics Syst Pharmacol
; 11(3): 333-347, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34971492
19.
Rigorous treatment of multispecies multimode ligand-receptor interactions in 3D-QSAR: CoMFA analysis of thyroxine analogs binding to transthyretin.
J Chem Inf Model
; 51(5): 1132-50, 2011 May 23.
Artigo
Inglês
| MEDLINE | ID: mdl-21476521
20.