RESUMO
An electrophoretic investigation of quantitative protein content in rat's' tissyes under chronic alcoholic intoxication has been done. It was shown the significant increase of protein content with molecular mass 55, 48-50, 43-45, 39-41 KDa and the decrease-of protein fractions with molecular mass 46-48, 34-35, 27-30, 16-18 KDa accordingly in liver and brain homogenates of experimental animals.
Assuntos
Alcoolismo/metabolismo , Encéfalo/efeitos dos fármacos , Etanol/toxicidade , Fígado/efeitos dos fármacos , Proteínas do Tecido Nervoso/metabolismo , Alcoolismo/fisiopatologia , Animais , Animais não Endogâmicos , Encéfalo/metabolismo , Química Encefálica , Eletroforese em Gel de Poliacrilamida , Feminino , Fígado/química , Fígado/metabolismo , Peso Molecular , Proteínas do Tecido Nervoso/isolamento & purificação , RatosRESUMO
The presence of hydrogen sulfide, methilmercaptane, dimethilsulfide, putrescine, cadaverine in exhaled air was evaluated in the study. The concentrations of the named substances were defined in various oral diseases. The received results are of interest for differential diagnostics of halitosis causes.
Assuntos
Ar/análise , Halitose/etiologia , Doenças da Boca/complicações , Doenças da Boca/diagnóstico , Bactérias/isolamento & purificação , Cadaverina/análise , Cromatografia Gasosa , Diagnóstico Diferencial , Expiração , Feminino , Humanos , Sulfeto de Hidrogênio/análise , Masculino , Doenças da Boca/microbiologia , Putrescina/análise , Compostos de Sulfidrila/análise , Sulfetos/análiseRESUMO
The structure of exhaled air at various somatopathies is evaluated in the study. Presence and concentration of hydrogen sulfide, dimethilsulfide, putrescine, cadaverine in patients with otolaryngological, endocrine pathology, diseases of gastrointestinal tract and oral diseases. The obtained data is of great importance for halitosis causes diagnostics.
Assuntos
Ar/análise , Halitose/diagnóstico , Halitose/etiologia , Doenças do Sistema Digestório/complicações , Doenças do Sistema Endócrino/complicações , Expiração , Feminino , Humanos , Sulfeto de Hidrogênio/análise , Masculino , Doenças da Boca/complicações , Otorrinolaringopatias/complicações , Putrescina/análise , Compostos de Sulfidrila/análise , Sulfetos/análiseRESUMO
The clinical manifestations and some immunological parameters (CD4 lymphocytes, CD4/CD8 ratio, IgM, IgA, IgG levels, skin test) were examined in 226 adult patients (148 males and 78 females) infected with HIV. These included 58 (26%) asymptomatic patients with seropositive test, 109 (48%) with the only clinical manifestation generalized lymphadenopathy; 54 (24%) with AIDS-related infections, 5 (2%) with AIDS. A subsequent follow-up of 3 months to 3 years demonstrated that AIDS developed in 7 patients, 9 died. The period of infection with HIV and death ranged from 1.5 to 9 years. The signs of cell immunodeficiency were found in 70% of the examinees. Recommendations are given on the classification of HIV infection.
Assuntos
Sorodiagnóstico da AIDS/métodos , Síndrome da Imunodeficiência Adquirida/diagnóstico , Infecções por HIV/diagnóstico , Síndrome da Imunodeficiência Adquirida/classificação , Síndrome da Imunodeficiência Adquirida/imunologia , Adulto , Idoso , Relação CD4-CD8 , Feminino , Infecções por HIV/imunologia , Humanos , Imunoglobulinas/análise , Contagem de Leucócitos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Linfócitos T/imunologia , Linfócitos T/patologia , Fatores de TempoRESUMO
The authors observed high incidence (100% among citizens of the USSR) and intensity of caries in 47 patients with diagnosed acquired HIV infection in the stage of symptom-free course and AIDS. In 2 persons out of 9 in symptom-free course of HIV infection an increase of mental lymph nodes has been observed. Significant changes of the mouth cavity mucosa were diagnosed in 67.1% of the patients. Gingivitis was observed three times as often than in the control group.
Assuntos
Síndrome da Imunodeficiência Adquirida/complicações , Saúde Bucal , Síndrome da Imunodeficiência Adquirida/epidemiologia , Adulto , África Central/etnologia , Índice CPO , Feminino , Humanos , Masculino , Doenças da Boca/epidemiologia , Doenças da Boca/etiologia , Doenças Periodontais/epidemiologia , Doenças Periodontais/etiologia , Índice Periodontal , Doenças Dentárias/epidemiologia , Doenças Dentárias/etiologia , U.R.S.S./epidemiologiaRESUMO
It was shown that the activity of interferon-induced enzyme 2',5'-oligoadenylate-synthetase is suppressed in rat spleen lymphocytes under the chronic alcohol intoxication. The values of enzyme activity were minimal under the long-term action of etanol (21 day). The combined administration of zinc acetate and etanol to rats causes the increase of enzyme activity, the effect is most expressed on the late stages of alcohol intoxication development.