Detalhe da pesquisa
1.
Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.
Mol Cell
; 77(3): 656-668.e5, 2020 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32004469
2.
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor.
Nature
; 561(7724): 492-497, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30209400
3.
Structure of the adenosine-bound human adenosine A1 receptor-Gi complex.
Nature
; 558(7711): 559-563, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29925945
4.
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.
Nature
; 555(7694): 121-125, 2018 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29466332
5.
Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.
Nature
; 546(7656): 118-123, 2017 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28437792
6.
Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends.
Nucleic Acids Res
; 48(10): 5735-5748, 2020 06 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32313946
7.
Isolation and Characterization of Metallosphaera Turreted Icosahedral Virus, a Founding Member of a New Family of Archaeal Viruses.
J Virol
; 91(20)2017 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28768871
8.
Subtomogram analysis using the Volta phase plate.
J Struct Biol
; 197(2): 94-101, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27235783
9.
Volta potential phase plate for in-focus phase contrast transmission electron microscopy.
Proc Natl Acad Sci U S A
; 111(44): 15635-40, 2014 Nov 04.
Artigo
Inglês
| MEDLINE | ID: mdl-25331897
10.
Removing Contamination-Induced Reconstruction Artifacts from Cryo-electron Tomograms.
Biophys J
; 110(4): 850-9, 2016 Feb 23.
Artigo
Inglês
| MEDLINE | ID: mdl-26743046
11.
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.
Nat Commun
; 15(1): 275, 2024 Jan 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38177131
12.
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation.
Nat Commun
; 13(1): 92, 2022 01 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35013280
13.
Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.
ACS Pharmacol Transl Sci
; 3(2): 263-284, 2020 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32296767
14.
Structure and dynamics of the active Gs-coupled human secretin receptor.
Nat Commun
; 11(1): 4137, 2020 08 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32811827
15.
Cryo-EM structure of haemoglobin at 3.2 Å determined with the Volta phase plate.
Nat Commun
; 8: 16099, 2017 06 30.
Artigo
Inglês
| MEDLINE | ID: mdl-28665412
16.
Revisiting the Structure of Hemoglobin and Myoglobin with Cryo-Electron Microscopy.
J Mol Biol
; 429(17): 2611-2618, 2017 08 18.
Artigo
Inglês
| MEDLINE | ID: mdl-28697886
17.
Volta phase plate cryo-EM of the small protein complex Prx3.
Nat Commun
; 7: 10534, 2016 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-26817416