Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 214
Filtrar
1.
BMC Public Health ; 24(1): 748, 2024 Mar 08.
Artigo em Inglês | MEDLINE | ID: mdl-38459451

RESUMO

BACKGROUND: Perceiving oneself as obese has been associated with weight loss attempts. However, such a perception may not sufficiently drive significant weight reduction in many individuals. Hence, relying solely on the traditionally emphasized perceived risk of behavioral changes in obesity is challenging. This study used an extended parallel process model and a risk perception attitude framework to explore the influence of perceived risk and perceived efficacy on individual obesity knowledge and obesity prevention behaviors. METHODS: Data were obtained from 1,100 Korean adults aged 40-69 years through an online survey conducted in October 2022. Multinomial logistic regression and analysis of variance were employed to assess the relationships among perceived risk, perceived efficacy, obesity knowledge, and obesity prevention behaviors. RESULTS: Sex was associated with being underweight, overweight, and obese. Moreover, perceived severity was associated with obesity, whereas perceived susceptibility was associated with overweight and obese. Response efficacy was related to being overweight alone, whereas self-efficacy was associated with being underweight, overweight, and obese. The main effects of sex and perceived risk, and their interaction effect were statistically significant for obesity knowledge. Additionally, the main effects of sex, perceived risk, and perceived efficacy on obesity prevention behaviors were statistically significant. CONCLUSIONS: The extended parallel process model and risk perception attitude framework proved effective in classifying obesity based on body mass index, obesity knowledge, and obesity prevention behaviors.


Assuntos
Sobrepeso , Magreza , Adulto , Humanos , Obesidade/prevenção & controle , Índice de Massa Corporal , Redução de Peso , Percepção , República da Coreia/epidemiologia , Peso Corporal
2.
Clin J Sport Med ; 34(4): 370-375, 2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-38174994

RESUMO

OBJECTIVE: The authors report no conflicts of interest.To determine baseline sleep characteristics of male/female student-athletes across multiple sports using objective and subjective measures. DESIGN: Prospective study. SETTING: Division I college. PARTICIPANTS: Eighty-two male and female Division I student-athletes. INTERVENTIONS: Participants completed 2 validated sleep questionnaires (Epworth Sleepiness Scale [ESS] and Single-Item Sleep Quality Scale [SISQS]) to assess subjective sleep. They also wore a validated sleep monitoring device (WHOOP 4.0 band) for at least 14 nights to collect objective data on total sleep time (TST) and sleep architecture. MAIN OUTCOME MEASURES: Overnight sleep variables, including TST, time spent awake in bed after falling asleep, time spent in light sleep, rapid eye movement (REM) sleep, and slow-wave sleep (SWS) cycles. Sleep quality and daytime sleepiness were also assessed. RESULTS: There were no statistical differences between male and female student-athletes in average TST, sleep architecture, sleep consistency, SISQS, and ESS scores. The average TST was 409.2 ± 36.3 minutes. Sleep architecture consisted of 25.6% REM, 19.9% SWS, and 54.4% light sleep. The average sleep consistency was 61.6% ± 8.9%. The average SISQS score was 6.48 ± 1.71, and the average ESS score was 7.57 ± 3.82. A significant difference was found in average wake time between males and females (55.0 vs 43.7 min, P = 0.020), with an overall average of 50.2 ± 16.2 minutes. CONCLUSIONS: College student-athletes do not typically obtain the recommended amount of sleep. Optimizing sleep can positively affect academic and athletic performance.


Assuntos
Atletas , Sono , Humanos , Masculino , Feminino , Estudos Prospectivos , Adulto Jovem , Sono/fisiologia , Universidades , Qualidade do Sono , Adolescente , Estudantes , Inquéritos e Questionários
3.
J Environ Manage ; 365: 121582, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38924887

RESUMO

As river ecosystems continue to face environmental pressures, it is crucial to develop and apply new biologically relevant statistical tools to support river health assessments. This study aimed to test the potential significance of nonmetric ordination scores and multidimensional functional indices of fish communities for analyzing river ecological health linked to variations in environmental factors. We conducted a nonmetric multidimensional scaling (NMDS) to derive ordination scores based on twenty fish ecological entities (FEs) that we newly defined, along with their relative abundance (RA). These FEs were determined through a unique combination of trophic, habitat, and tolerance guilds. Additionally, we calculated the functional diversity and identity (F-Ide) indices using the RA-weighted distances between FEs defined by the guild identities in a multidimensional space. The results showed that these novel analyses were helpful in assessing river ecological health and spatial changes in the environment. The dominant F-Ide in each community was largely responsible for the variation of river health scores, driven by the combined impact of chemical water quality, alterations in substrate composition, land use changes, and the gradient of elevation. These environmental factors significantly influenced the site scores in the first axis of NMDS, F-Ide indices, and river health scores. Therefore, our study highlights the practical value of utilizing nonmetric scaling ordination scores of FEs and F-Ide indices as tools for evaluating the health of river ecosystems. By elucidating fish community variance, these tools can aid in determining the extent of river health degradation attributable to environmental stressors, including chemical water pollution and changes in substrate resulting from changes in land use and at different elevations.


Assuntos
Ecossistema , Peixes , Rios , Animais , Monitoramento Ambiental/métodos , Biodiversidade , Qualidade da Água , Ecologia
4.
Int J Dent Hyg ; 2024 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-38659166

RESUMO

OBJECTIVES: This study aimed to determine the overall oral health statuses of patients with fixed orthodontic appliance and clear aligner, as well as their oral hygiene management behaviours and satisfaction. METHODS: We selected 40 participants (20 each with fixed orthodontic devices and clear aligners) who visited a dental clinic. We conducted a survey to determine the oral hygiene management behaviours of the subjects and their satisfaction with their orthodontic treatment. Three measurements were also conducted at 4-week intervals to determine the oral health statuses of the subjects. RESULTS: The Löe and Silness gingival index of patients with fixed orthodontic appliances indicated moderate gingivitis (1.1 ± 0.3), and those with clear aligners had mild gingivitis (0.6 ± 0.4) (p < 0.001). The modified O'Leary index also indicated that the degree of dental plaque deposition in the oral cavity was lower in patients treated with a clear aligner (43.0 ± 18.2 points) than in those treated with a fixed orthodontic (28.1 ± 10.9 points) (p = 0.004). Regarding oral hygiene management, the fixed orthodontic group received scaling more frequently (p = 0.006), received more oral health education (p < 0.001) and had a longer brushing time (p = 0.008) than the clear aligner group. No significant difference was observed in satisfaction between the fixed orthodontic appliance and the clear aligner. CONCLUSIONS: Regarding the oral health status by orthodontic appliance type, the clear aligner group had the advantages of reduction in dental plaque attachment and gingival health. The fixed orthodontic group exhibited better oral hygiene management behaviours. Satisfaction with orthodontic treatment was found to be similar for the two device types.

5.
Ann Surg ; 278(4): 497-505, 2023 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-37389574

RESUMO

OBJECTIVE: We sought to quantify the effects of in-house call(IHC) on sleep patterns and burnout among acute care surgeons (ACS). BACKGROUND: Many ACS take INC, which leads to disrupted sleep and high levels of stress and burnout. METHODS: Physiological and survey data of 224 ACS with IHC were collected over 6 months. Participants continuously wore a physiological tracking device and responded to daily electronic surveys. Daily surveys captured work and life events as well as feelings of restfulness and burnout. The Maslach Burnout Inventory (MBI) was administered at the beginning and end of the study period. RESULTS: Physiological data were recorded for 34,135 days, which includes 4389 nights of IHC. Feelings of moderate, very, or extreme burnout occurred 25.7% of days and feelings of being moderately, slightly, or not at all rested occurred 75.91% of days. Decreased amount of time since the last IHC, reduced sleep duration, being on call, and having a bad outcome all contribute to greater feelings of daily burnout ( P <0.001). Decreased time since last call also exacerbates the negative effect of IHC on burnout ( P <0.01). CONCLUSIONS: ACS exhibit lower quality and reduced amount of sleep compared with an age-matched population. Furthermore, reduced sleep and decreased time since the last call led to increased feelings of daily burnout, accumulating in emotional exhaustion as measured on the MBI. A reevaluation of IHC requirements and patterns as well as identification of countermeasures to restore homeostatic wellness in ACS is essential to protect and optimize our workforce.


Assuntos
Esgotamento Profissional , Cirurgiões , Humanos , Visita Domiciliar , Cirurgiões/psicologia , Sono/fisiologia , Esgotamento Profissional/psicologia , Inquéritos e Questionários
6.
Exp Dermatol ; 32(6): 822-830, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-36843342

RESUMO

The current study aimed to characterize cellular uptake and bioconversion of retinol in fully differentiated human immortalized keratinocytes cells (HaCaT) and artificial skin by measuring the cell integrity of skin barriers, time-dependent transport of retinol, and bioconversion to its metabolites. The expression of epidermal differentiation related genes including Keratin 1 (KRT1), Keratin 10 (KRT10), and Involucrin (IVL) significantly increased in differentiated HaCaT. TEER of HaCaT did not decrease after incubating retinol compared to control (p > 0.05), indicating that retinol tends to maintain strength and integrity of epidermal barrier. TEER of artificial skin decreased treatment of retinol for 2 h, but it was recovered after 4 h. During retinol transport, metabolite was eluted at 13.37 and 13.82 min of basal medium of both keratinocytes and artificial skin, which was identified as retinoic acid by product ion of m/z 283.47. Retinol appeared to be accumulated in keratinocytes, but its uptake tends to be reduced in a time-dependent manner. Retinoic acid converted from retinol in keratinocytes was time dependently transported. In case of artificial skin, retinol was mostly found in apical at initial incubation time, but it was reduced during incubation for 24 h. Retinoic acid was time-dependently found in a basal, which was converted via epidermis-dermis. Results from the current study suggest that topical application of retinol to human skin optimal concentration and time exposure could maintain epidermal barrier function and promote skin function due to its remarkable bioconversion to retinoic acid in the epidermis-dermis.


Assuntos
Pele Artificial , Vitamina A , Humanos , Queratinócitos/metabolismo , Epiderme/metabolismo , Tretinoína/metabolismo , Derme/metabolismo
7.
J Vasc Interv Radiol ; 34(4): 591-599.e1, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36526076

RESUMO

PURPOSE: To assess outcome and predictors of outcome after lymphatic embolization (LE) for early postoperative lymphatic leak after pelvic surgery. MATERIAL AND METHODS: Lymphangiography (LG) procedures performed between May 2015 and February 2020 for postoperative intraperitoneal lymphatic leaks after pelvic surgery were reviewed. Treatment indication was lymphatic drainage of >500 mL/d persisting for >1 week. LE was performed by injecting glue into the iliac lymph node. Fisher exact and Wilcoxon rank-sum tests were used for comparative analysis, and logistic regression was used to assess predictors of outcome. RESULTS: LG was performed in 71 patients. A leak was demonstrated in 69 patients who underwent LE. The mean drainage was 1,329 mL/d ± 773. Catheters were removed in 49 (69.0%) patients after 1 procedure and in 69 (97.2%) patients after a mean of 1.3 procedures. The mean drainage at the time of catheter removal was 157 mL/d ± 100. Failure occurred in 12 (16.9%) cases, including 2 (2.8%) cases of unsuccessful catheter removal and 10 (14.1%) cases of catheter reinsertion owing to recurrent ascites (n = 3) and lymphoceles (n = 7). Older age and drainage of >1,500 mL/d were associated with failure (P = .004). Drainage of >1,500 mL/d was associated with a post-LE catheter dwell time of longer than 1 week (P = .024). Minor adverse events were noted in 4 (5.6%) patients who presented with transient leg swelling. CONCLUSIONS: LE was effective for treating pelvic surgery-related lymphatic leaks. Reintervention may be required. Drainage of >1,500 mL/d was associated with clinical failure and a post-LE catheter dwell time of longer than 1 week.


Assuntos
Embolização Terapêutica , Vasos Linfáticos , Linfocele , Humanos , Linfografia/métodos , Resultado do Tratamento , Embolização Terapêutica/efeitos adversos , Linfocele/diagnóstico por imagem , Linfocele/etiologia , Linfocele/terapia , Estudos Retrospectivos
8.
Fish Shellfish Immunol ; 138: 108804, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37207886

RESUMO

Cystatins are natural inhibitors of lysosomal cysteine proteases, including cathepsins B, L, H, and S. Cystatin C (CSTC) is a member of the type 2 cystatin family and is an essential biomarker in the prognosis of several diseases. Emerging evidence suggests the immune regulatory roles of CSTC in antigen presentation, the release of different inflammatory mediators, and apoptosis in various pathophysiologies. In this study, the 390-bp cystatin C (HaCSTC) cDNA from big-belly seahorse (Hippocampus abdominalis) was cloned and characterized by screening the pre-established cDNA library. Based on similarities in sequence, HaCSTC is a homolog of the teleost type 2 cystatin family with putative catalytic cystatin domains, signal peptides, and disulfide bonds. HaCSTC transcripts were ubiquitously expressed in all tested big-belly seahorse tissues, with the highest expression in ovaries. Immune challenge with lipopolysaccharides, polyinosinic:polycytidylic acid, Edwardsiella tarda, and Streptococcus iniae caused significant upregulation in HaCSTC transcript levels. Using a pMAL-c5X expression vector, the 14.29-kDa protein of recombinant HaCSTC (rHaCSTC) was expressed in Escherichia coli BL21 (DE3), and its protease inhibitory activity against papain cysteine protease was determined with the aid of a protease substrate. Papain was competitively blocked by rHaCSTC in a dose-dependent manner. In response to viral hemorrhagic septicemia virus (VHSV) infection, HaCSTC overexpression strongly decreased the expression of VHSV transcripts, pro-inflammatory cytokines, and pro-apoptotic genes; while increasing the expression of anti-apoptotic genes in fathead minnow (FHM) cells. Furthermore, HaCSTC overexpression protected VHSV-infected FHM cells against VHSV-induced apoptosis and increased cell viability. Our findings imply the profound role of HaCSTC against pathogen infections by modulating fish immune responses.


Assuntos
Smegmamorpha , Animais , Cistatina C/genética , Papaína/genética , Streptococcus iniae/fisiologia , Poli I-C/farmacologia , Proteínas de Peixes/química , Filogenia
9.
Fish Shellfish Immunol ; 133: 108552, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36669605

RESUMO

Peroxiredoxin 1 is a member of the typical 2-Cys peroxiredoxin family, which serves diverse functions in gene expression, immune and inflammatory responses, and tumor progression. In this study, we aimed to analyze the structural, functional, and immunomodulatory properties of peroxiredoxin 1 from Epinephelus akaara (EaPrx1). The open reading frame of EaPrx1 is 597 base pairs in length, encoding 198 amino acids, with a molecular weight of approximately 22 kDa. The in silico analysis revealed that EaPrx1 shares a conserved thioredoxin fold and signature motifs that are critical for its catalytic activity and oligomerization. Further, EaPrx1 is closely related to Epinephelus lanceolatus Prx1 and clustered in the Fishes group of the vertebrate clade, revealing that EaPrx1 was conserved throughout evolution. In terms of tissue distribution, a high level of EaPrx1 expression was observed in the spleen, brain, and blood tissues. Likewise, in immune challenge experiments, significant transcriptional modulations of EaPrx1 upon lipopolysaccharide, polyinosinic:polycytidylic acid, and nervous necrosis virus injections were noted at different time points, indicating the immunological role of EaPrx1 against pathogenic infections. In the functional analysis, rEaPrx1 exhibited substantial DNA protection, insulin disulfide reduction, and tissue repair activities, which were concentration-dependent. EaPrx1/pcDNA™ 3.1 (+)-transfected fathead minnow cells revealed high cell viability upon arsenic toxicity, indicating the heavy metal detoxification activity of EaPrx1. Taken together, the transcriptional and functional studies imply critical roles of EaPrx1 in innate immunity, redox regulation, apoptosis, and tissue-repair processes in E. akaara.


Assuntos
Bass , Doenças dos Peixes , Animais , Peroxirredoxinas/genética , Peroxirredoxinas/química , Bass/genética , Bass/metabolismo , Imunidade Inata/genética , Antioxidantes/metabolismo , Oxirredução , Filogenia , Regulação da Expressão Gênica , Proteínas de Peixes/química
10.
Anal Biochem ; 647: 114650, 2022 06 15.
Artigo em Inglês | MEDLINE | ID: mdl-35331694

RESUMO

Sialylated and core-fucosylated N-glycans in human transferrin (HTF) are used as glycan biomarkers due to their increased or decreased characteristics in certain diseases. However, their absolute quantities remain unclear. In this study, N-glycans of HTF were identified by UPLC and LC-MS/MS using fluorescence tags [2-aminobenzamide (AB) and procainamide (ProA)] and columns [HILIC and anion exchange chromatography-HILIC (AXH)]. The structures of 14 (including five core-fucosylated) N-glycans in total comprising two non-, six mono-, four di-, and two tri-sialylated N-glycans were identified. The quantities (%) of each N-glycan relative to the total N-glycans (100%) were obtained. HILIC and AXH were better for peak identification and separability except for desialylation, respectively. Specifically, sialylated (in ProA-HILIC and ProA-AXH by UPLC or LC-MS/MS) and core-fucosylated (in AB-HILIC and ProA-AXH by UPLC) N-glycans were efficiently identified. Seven neuraminidase-treated (including three core-fucosylated) N-glycans were efficiently identified in ProA-AXH, even their poor separation. Additionally, ProA-AXH was more efficient for the estimation of the absolute quantities of N-glycans from the results of fluorescence intensity (by UPLC) and relative quantity (by LC-MS/MS). These results first demonstrate that ProA is useful for identifying and quantifying sialylated, core-fucosylated, and neuraminidase-treated desialylated N-glycans in HTF using AXH by UPLC and LC/MS.


Assuntos
Espectrometria de Massas em Tandem , Transferrina , Cromatografia Líquida , Humanos , Neuraminidase , Polissacarídeos/química
11.
Comput Inform Nurs ; 40(10): 725-733, 2022 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-35524364

RESUMO

Much of the research on nursing informatics competence has been conducted in a Western context. Thus, this study aimed to develop the Korean Nursing Informatics Competence Assessment Scale for clinical nurses and to evaluate its validity and reliability. A total of 52 items were derived based on the hybrid model. After a content validity test by six experts and item evaluation by 20 nurses, the scale was revised to include 35 items. For this study, 214 nurses completed the nursing informatics competence assessment scale to verify the scale's reliability and validity. Confirmatory factor analysis revealed five factors composed of 20 items; the fit index of the derived model was good. A positive correlation between scores on the nursing informatics competence scale and the patient safety competence scale ( r = .66, P < .001) was found for the criterion-related validity test. Cronbach's α was .91, indicating that the instrument is reliable and stable. Overall, this study provides preliminary evidence for the validity and reliability of the Korean nursing informatics competence assessment scale to evaluate clinical nurses. This study contributes to the understanding and improvement of nursing informatics competence by providing a reliable scale for assessing clinical nursing practice.


Assuntos
Informática em Enfermagem , Competência Clínica , Humanos , Psicometria , Reprodutibilidade dos Testes , República da Coreia , Inquéritos e Questionários
12.
Telemed J E Health ; 27(6): 670-678, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33095109

RESUMO

Background: This study aimed to investigate the needs of medical users of telemedicine robots to encourage international cooperation and development. Introduction: As the use of telemedicine expands, it is necessary to develop new systems, including robots, which consider the perceived needs of end users to ensure quality of care and positive user experience. Materials and Methods: A survey of medical staff was conducted at a hospital in Vietnam to investigate users' needs for a telemedicine robot system. Results: A total of 117 medical staff participated in the survey, comprising 74 nurses and 43 doctors. The most preferred type of robot was the humanoid type, female version, and the preferred mobility type was walking. The most requested functions were "heart rate measurement," "recognition and avoidance of obstacles," "oxygen saturation measurement," "Transmitting Medical Information," and "wireless system." In addition, the most important considerations in developing a robot system were "cleaning the robot to prevent infection," followed by "convenience of operation." Discussion: The results of this study largely supported those of similar previous studies. However, some differences may reflect the cultural variation or differences in the level of medical development across contexts. Conclusion: To apply robotic systems to help develop telemedicine internationally, it is essential to develop a robot that reflects actual users' needs. If relevant matters such as legal issues are considered and addressed, an appropriate robotic telemedicine system can be successfully developed. Consequently, telemedicine can improve the quality of local medical care, strengthen practitioner capacity, and improve outcomes.


Assuntos
Robótica , Telemedicina , Países em Desenvolvimento , Feminino , Hospitais , Humanos , Inquéritos e Questionários
13.
Cytokine ; 127: 154983, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31918161

RESUMO

Inflammasome activation induces the maturation and secretion of interleukin (IL)-1ß and -18, and is dependent on NF-κB signaling to induce the transcription of the inflammasome components, called the priming step. This study elucidated the role of IκBζ, an atypical IκBs (inhibitor of κB) and a coactivator of NF-κB target genes, on the activation of inflammasome. Bone marrow-derived macrophages (BMDMs) that originated from IκBζ-encoding Nfkbiz gene depletion mice presented a defect in NLRP3 inflammasome activation. In addition, the Nfkbiz+/- and Nfkbiz-/- mice significantly attenuated serum IL-1ß secretion in response to a monosodium urate injection, a NLRP3 trigger, when compared with Nfkbiz-+/+ mice. The lack of IκBζ in BMDMs produced a disability in the expression of Nlrp3 and pro-Il1ß mRNAs during the priming step. In addition, ectopic IκBζ expression enhanced the Nlrp3 promoter activity, and Nlrp3 and pro-Il1ß transcription. Overall, IκBζ controlled the activation of NLRP3 inflammasome by upregulating the Nlrp3 gene during the priming step.


Assuntos
Proteínas Adaptadoras de Transdução de Sinal/genética , Inflamassomos/genética , Proteína 3 que Contém Domínio de Pirina da Família NLR/genética , Regulação para Cima/genética , Animais , Células Cultivadas , Macrófagos/metabolismo , Camundongos , Regiões Promotoras Genéticas/genética , Células RAW 264.7 , RNA Mensageiro/genética , Transdução de Sinais/genética , Transcrição Gênica/genética
14.
Telemed J E Health ; 26(9): 1134-1140, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-31971885

RESUMO

Background: Through information and communication technology, telemedicine can deliver medical care without time and place restrictions, increasing health care accessibility in medically underdeveloped regions. Although there is growing interest in using robots in telemedicine, there are few economic evaluation studies of robot-based telemedicine. Introduction: Robots developed for use in telemedicine consultation services may help address the challenges that result from Korean physicians' efforts to support patients in Vietnam. We perform a cost-benefit analysis to assess the economic feasibility of a robot-based telemedicine consultation system compared with traditional face-to-face outpatient services. Methods: A cost-benefit analysis is performed of a robot-based telemedicine consultation system between S Hospital in Korea and H Hospital in Vietnam. The threshold was calculated as the point at which the cost of providing telemedicine consultation equals the cost of providing the same service using traditional methods. Results: The annual cost of a robot-based telemedicine consultation system was estimated as 6,056.40 USD, whereas the annual benefit from replacing traditional outpatient services was estimated as 1,508.51 USD, resulting in a threshold point of 4.01 visits per year. Consequently, if the telemedicine consultation robot system replaces >4.01 physician visits per year, it is more economical than conventional face-to-face services. If the physician needs to stay longer, the threshold will be lower. Conclusions: As our results show, robot-based systems for telemedicine have economic value and can potentially offer a solution to the unmet health care needs among patients living in medically underdeveloped regions by providing proper and timely medical care.


Assuntos
Robótica , Telemedicina , Análise Custo-Benefício , Humanos , Encaminhamento e Consulta , República da Coreia
15.
Comput Inform Nurs ; 38(7): 349-357, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31009402

RESUMO

The purpose of this study was to investigate nurses' need for care robots in children's hospitals and to help develop care robots that can be used by combining robot-care, game-care, and edu-care. This study employed a mixed-methods design; 198 nurses were recruited for quantitative research and 12 for qualitative research. The findings were as follows. Robot-care: Participants had an overwhelming preference for robots made of plastic or steel that could easily be washed and sterilized. Game-care: Among nursing procedures, vital sign measurements were the most common actions that could be implemented using game elements. Edu-care: The educational content that participants felt should be presented to child patients and caregivers through care robots included information about hospitalization, discharge, infection control, falls, and pressure ulcer prevention. Qualitative data divided the role of care robots into five subcategories associated with children and one subcategory associated with guardians. The findings of this study are meaningful in that it clarified the needs of nurses in the development of care robots for use in children's hospitals.


Assuntos
Enfermeiras e Enfermeiros/psicologia , Robótica/tendências , Adulto , Cuidadores/psicologia , Feminino , Hospitais Pediátricos/organização & administração , Hospitais Pediátricos/tendências , Humanos , Masculino , Pessoa de Meia-Idade , Educação de Pacientes como Assunto/métodos , Educação de Pacientes como Assunto/tendências , Papel Profissional/psicologia , Pesquisa Qualitativa , Robótica/métodos , Inquéritos e Questionários
16.
Comput Inform Nurs ; 38(1): 8-17, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31524689

RESUMO

Robotic systems are used to support inpatients and healthcare professionals and to improve the efficiency and quality of nursing. There is a lack of scientific literature on how applied robotic systems can be used to support inpatients. This study uses surveys and focus group interviews to identify the necessary aspects and functions of bedside robots for inpatients. A total of 90 healthcare professionals and 108 inpatients completed the questionnaire, and four physicians and five nurses participated in the focus group interviews. The most highly desired functionalities were related to patient care and monitoring, including alerting staff, measuring vital signs, and sensing falls. Nurses and physicians reported different needs for human-robot interaction. Nurses valued robotic functions such as nonverbal expression recognition, automatic movement, content suggestion, and emotional expressions. The results of the patients' open-ended questions and healthcare professionals' focus groups indicate that the purpose of the robots should primarily be treatment and nursing. Participants believe bedside robots would be helpful but have concerns regarding safety and utility. This study attempts to determine which aspects of robots may increase their acceptance. Our findings suggest that if robots are used in healthcare institutions, they may improve the effectiveness of care.


Assuntos
Pessoal de Saúde/estatística & dados numéricos , Pacientes Internados/estatística & dados numéricos , Sistemas Automatizados de Assistência Junto ao Leito , Robótica/instrumentação , Acidentes por Quedas/prevenção & controle , Adulto , Feminino , Grupos Focais , Humanos , Internet , Masculino , Monitorização Fisiológica/estatística & dados numéricos , Informática em Enfermagem , Satisfação do Paciente/estatística & dados numéricos , Inquéritos e Questionários
17.
Fish Shellfish Immunol ; 86: 230-238, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30458312

RESUMO

Arachidonate 5-lipoxygenase (ALOX5) is an essential enzyme for the biosynthesis of leukotrienes, which are pro-inflammatory and anti-inflammatory mediators. In this study, the ALOX5 paralog of the big-belly seahorse (Hippocampus abdominalis; HaALOX5) was identified from our transcriptome database, and then molecularly and functionally characterized to determine its oxygenation capability and expression under pathogenic stress. The coding sequence of HaALOX5 consisted of 2025 bp and encoded a protein of 674 amino acids in length. Sequence and phylogenetic tree analysis of HaALOX5 revealed a close relationship with its corresponding teleost HaALOX5 counterparts. Structure prediction detected an N-terminal regulatory C2-like domain and a C-terminal catalytic domain, which are the two main functional domains in ALOX5 enzymes. Quantitative PCR showed that HaALOX5 was expressed in all the analyzed tissues at different magnitudes. The highest expression was detected in the intestine and stomach. In blood cells, the liver and the intestine, HaALOX5 transcripts were significantly elevated at many post injection time points, when immune challenged with lipopolysaccharide, polyinosinic:polycytidylic acid, and Streptococcus iniae, indicating its contribution to post immune defense mechanisms in the seahorse.


Assuntos
Araquidonato 5-Lipoxigenase/química , Proteínas de Peixes/imunologia , Smegmamorpha/imunologia , Sequência de Aminoácidos , Animais , Araquidonato 5-Lipoxigenase/genética , Araquidonato 5-Lipoxigenase/imunologia , Doenças dos Peixes/genética , Doenças dos Peixes/imunologia , Proteínas de Peixes/química , Proteínas de Peixes/genética , Lipopolissacarídeos/farmacologia , Filogenia , Poli I-C/farmacologia , Smegmamorpha/genética , Infecções Estreptocócicas/imunologia , Infecções Estreptocócicas/veterinária , Streptococcus iniae/imunologia
18.
Am J Emerg Med ; 37(9): 1649-1656, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-30522934

RESUMO

BACKGROUND: Whether or not short-term exposure to particulate matter <2.5 µm in diameter (PM2.5) increases the risk of psychiatric emergency diseases is unclear. METHODS: The study was performed in a metropolis from January 2015 to December 2016. The exposure was PM2.5, and the confounders were weather (temperature and humidity) and other pollutants (PM10, SO2, CO, O3, and NO2). The outcomes were emergency department (ED) visits with psychiatric disease codes (F00-F99 in ICD10 codes). General additive models were used for the statistical analysis to calculate the adjusted relative risks (ARRs) and 95% confidence intervals (95% CIs) for the daily number of ED visits with a lag of 1 to 3 days following a 10 µg/m3 increase in PM2.5. RESULTS: During the study period, a total of 67,561 ED visits for psychiatric diseases were identified and tested for association with PM2.5. Daily ED visits for all psychiatric diseases were not associated with PM2.5 in the model that was not adjusted for other pollutants. The ARR (95% CI) in the model adjusted for SO2 was 1.011 (1.002-1.021) by 10 µg/m3 of PM2.5 on Lag 1 for all psychiatric diseases (F00-F99). The ARR (95% CI) in the model adjusted for O3 was 1.015 (1.003-1.029) by 10 µg/m3 of PM2.5 on Lag 1 for F40-F49 (Neurotic, stress-related and somatoform disorders). CONCLUSION: An increase in PM2.5 showed a significant association with an increase in ED visits for all psychiatric diseases (F00-F99) and for neurotic, stress-related and somatoform disorders (F40-F49) on lag day 1.


Assuntos
Poluição do Ar/estatística & dados numéricos , Emergências/epidemiologia , Serviço Hospitalar de Emergência/estatística & dados numéricos , Transtornos Mentais/epidemiologia , Material Particulado , Adolescente , Adulto , Idoso , Feminino , Humanos , Umidade , Masculino , Pessoa de Meia-Idade , Transtornos Neuróticos , República da Coreia/epidemiologia , Risco , Estações do Ano , Transtornos Somatoformes , Estresse Psicológico , Temperatura , Tempo (Meteorologia) , Adulto Jovem
19.
Telemed J E Health ; 25(12): 1165-1173, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-30785857

RESUMO

Background: Development of a point-of-care (POC) consultation system based on telepresence robots is needed to enable effective decision-making by medical staff at care sites.Introduction: This study aimed to identify essential features and functional requirements of teleconsultation robot systems and predict potential administrative and clinical issues.Materials and Methods: Surveys were conducted with 90 health care professionals and additional focus group interviews with 4 physicians and 5 nurses. The questionnaire for the surveys was developed by the authors. Survey results were analyzed using descriptive statistics, and content analysis was used to extract themes from the unabridged transcripts of focus group interviews.Results: The most desired functionalities were related to patient evaluation and facilitation of communication, including measuring vital signs, and medical record sharing and delivery. Nurses and physicians reported different needs for human-robot interactions. Nurses valued robotic functions such as voice command, automatic camera movement, voice recognition with contextual perception, and recognition of nonverbal signals. The thematic analysis of the interviews yielded four themes: major functions, usability, expected effects, and potential issues. The results indicated that robots should primarily be employed to support communication between medical professionals. The major expected effects included prevention of treatment delays and decision-making assistance. Participants believed that teleconsultation robots would be helpful, but had concerns, including anxiety about the robots and judgment errors.Conclusions: Using robots in health care institutions may support effective communication among medical staff, thus contributing to health care improvement. In the future, an actual POC robot system will be developed and its effectiveness evaluated.


Assuntos
Atitude do Pessoal de Saúde , Avaliação das Necessidades , Sistemas Automatizados de Assistência Junto ao Leito , Consulta Remota , Robótica/métodos , Adulto , Tomada de Decisões , Feminino , Grupos Focais , Humanos , Masculino , Inquéritos e Questionários
20.
Comput Inform Nurs ; 37(2): 107-115, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30407214

RESUMO

Recent rapid development of medical and information technology has enabled the use of appropriate techniques for the delivery of healthcare. This project involved prediction of the meaning and structure of future health services, which are now commonly described through various keywords, without establishment of the concepts. The objectives of this study were to identify key concepts and values about future health services and to categorize the prediction of those from the perspectives of the concerned professionals using Q-methodology with 50 selected Q-statements. A total of 53 participants performed the Q-sort task using the 50 statements; collected data were analyzed using an associated program, pc-QUANL. Fifty Q-samples were selected to sort the concepts, and 53 professionals sorted the Q-samples. Six concepts were summarized, namely, the Optimistic Innovation Positive Type, Pessimistic Resistance to Technology-Driven Medicine Type, Intelligent Information Technology Centered Type, Bio-technology Centered Type, Personal Health Data Centered Type, and Customized Care Centered Type. The results could be used in the future design of consumer-centered health services. Advanced technology may accommodate the individual needs of different stakeholders and carve an ecosystem-wide suite of interacting complex adaptive systems.


Assuntos
Atenção à Saúde/tendências , Serviços de Saúde/tendências , Q-Sort , Previsões , Humanos
SELEÇÃO DE REFERÊNCIAS
Detalhe da pesquisa