Detalhe da pesquisa
1.
Cutting Edge: Induced Loss of Rasgrp1 in Peripheral CD4+ T Cells of Conditional Rasgrp1-Deficient Mice Reveals an Essential Role for Rasgrp1 in TCR/CD28-Induced Ras-MAPK Signaling.
J Immunol
; 211(6): 917-922, 2023 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37566514
2.
A temporally-restricted pattern of endothelial cell collagen 4 alpha 1 expression during embryonic development determined with a novel knockin Col4a1-P2A-eGFP mouse line.
Genesis
; 62(1): e23539, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-37501352
3.
RASA1-driven cellular export of collagen IV is required for the development of lymphovenous and venous valves in mice.
Development
; 147(23)2020 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33144395
4.
Mechanisms and functions of endocytosis in T cells.
Cell Commun Signal
; 19(1): 92, 2021 09 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34503523
5.
Simplified method to quantify valve back-leak uncovers severe mesenteric lymphatic valve dysfunction in mice deficient in connexins 43 and 37.
J Physiol
; 598(12): 2297-2310, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32267537
6.
Orbital- and k_{z}-Selective Hybridization of Se 4p and Ti 3d States in the Charge Density Wave Phase of TiSe_{2}.
Phys Rev Lett
; 122(7): 076404, 2019 Feb 22.
Artigo
Inglês
| MEDLINE | ID: mdl-30848608
7.
Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.
J Immunol
; 195(1): 31-5, 2015 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26002977
8.
Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.
Blood
; 123(10): 1574-85, 2014 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-24385536
9.
Lymphatic abnormalities are associated with RASA1 gene mutations in mouse and man.
Proc Natl Acad Sci U S A
; 110(21): 8621-6, 2013 May 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23650393
10.
Nonreceptor tyrosine phosphatase Shp2 promotes adipogenesis through inhibition of p38 MAP kinase.
Proc Natl Acad Sci U S A
; 110(1): E79-88, 2013 Jan 02.
Artigo
Inglês
| MEDLINE | ID: mdl-23236157
11.
Blood vascular abnormalities in Rasa1(R780Q) knockin mice: implications for the pathogenesis of capillary malformation-arteriovenous malformation.
Am J Pathol
; 184(12): 3163-9, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25283357
12.
The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease.
Blood
; 122(25): 4119-28, 2013 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-24141370
13.
The transition from stem cell to progenitor spermatogonia and male fertility requires the SHP2 protein tyrosine phosphatase.
Stem Cells
; 32(3): 741-53, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24123360
14.
T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells.
J Immunol
; 190(11): 5818-28, 2013 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23636056
15.
Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells.
Proc Natl Acad Sci U S A
; 109(40): 16264-9, 2012 Oct 02.
Artigo
Inglês
| MEDLINE | ID: mdl-22988097
16.
A role for p120 RasGAP in thymocyte positive selection and survival of naive T cells.
J Immunol
; 187(1): 151-63, 2011 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21646295
17.
The T-cell-specific adapter protein family: TSAd, ALX, and SH2D4A/SH2D4B.
Immunol Rev
; 232(1): 240-54, 2009 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-19909368
18.
EPHB4-RASA1-Mediated Negative Regulation of Ras-MAPK Signaling in the Vasculature: Implications for the Treatment of EPHB4- and RASA1-Related Vascular Anomalies in Humans.
Pharmaceuticals (Basel)
; 16(2)2023 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-37259315
19.
An EPHB4-RASA1 signaling complex inhibits shear stress-induced Ras-MAPK activation in lymphatic endothelial cells to promote the development of lymphatic vessel valves.
bioRxiv
; 2023 Nov 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38045382
20.
Essential role of the T cell-specific adapter protein in the activation of LCK in peripheral T cells.
J Exp Med
; 203(2): 281-7, 2006 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-16446380