Detalhe da pesquisa
1.
The contribution of extrachromosomal DNA to genome plasticity in malaria parasites.
Mol Microbiol
; 115(4): 503-507, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33103309
2.
Susceptibilities of Ugandan Plasmodium falciparum Isolates to Proteasome Inhibitors.
Antimicrob Agents Chemother
; 66(10): e0081722, 2022 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36094216
3.
Rapid antigen diversification through mitotic recombination in the human malaria parasite Plasmodium falciparum.
PLoS Biol
; 17(5): e3000271, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31083650
4.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
Proc Natl Acad Sci U S A
; 115(29): E6863-E6870, 2018 07 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29967165
5.
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice.
Angew Chem Int Ed Engl
; 60(17): 9279-9283, 2021 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33433953
6.
A Histone Methyltransferase Inhibitor Can Reverse Epigenetically Acquired Drug Resistance in the Malaria Parasite Plasmodium falciparum.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32179524
7.
Clinical and Molecular Evidence of Atovaquone and Azithromycin Resistance in Relapsed Babesia microti Infection Associated With Rituximab and Chronic Lymphocytic Leukemia.
Clin Infect Dis
; 65(7): 1222-1225, 2017 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28541469
8.
Babesia microti: from Mice to Ticks to an Increasing Number of Highly Susceptible Humans.
J Clin Microbiol
; 55(10): 2903-2912, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28747374
9.
Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity.
Nucleic Acids Res
; 42(1): 370-9, 2014 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24089143
10.
Origin of robustness in generating drug-resistant malaria parasites.
Mol Biol Evol
; 31(7): 1649-60, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24739308
11.
Direct evidence for the adaptive role of copy number variation on antifolate susceptibility in Plasmodium falciparum.
Mol Microbiol
; 88(4): 702-12, 2013 May.
Artigo
Inglês
| MEDLINE | ID: mdl-23347134
12.
Protocol for analysis of intracellular conversion of artezomib molecules into new proteasome inhibitors in Plasmodium falciparum parasites.
STAR Protoc
; 5(1): 102896, 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38363687
13.
Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.
Nat Commun
; 14(1): 8302, 2023 Dec 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38097652
14.
Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome InhibitorsâPart II.
J Med Chem
; 66(2): 1484-1508, 2023 01 26.
Artigo
Inglês
| MEDLINE | ID: mdl-36630286
15.
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.
Cell Chem Biol
; 30(5): 457-469.e11, 2023 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-37148884
16.
Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome.
Cell Chem Biol
; 30(5): 470-485.e6, 2023 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36963402
17.
Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors.
J Med Chem
; 65(13): 9350-9375, 2022 07 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35727231
18.
Telomere length dynamics in response to DNA damage in malaria parasites.
iScience
; 24(2): 102082, 2021 Feb 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33644714
19.
Vive la Différence: Exploiting the Differences between Rodent and Human Malarias.
Trends Parasitol
; 36(6): 504-511, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32407681
20.
Case Report: Mucosal Leishmaniasis in New York City.
Am J Trop Med Hyg
; 102(6): 1319-1322, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32228792