RESUMO
This study analyzed the pacing employed by young runners in 10,000 m time-trials under 3 dietary regimens of different carbohydrate (CHO) intakes. Nineteen boys (13-18 years) ate either their normal CHO diet (56% CHO), high (70% CHO), or low (25% CHO) CHO diets for 48 hr; the boys then performed a 10,000 m run (crossover design). The high CHO diet led to faster final sprint (14.4 ± 2.2 km·h⻹) and a better performance (50.0 ± 7.0 min) compared with the low CHO diet (13.3 ± 2.4 km·h⻹ and 51.9 ± 8.3 min, respectively, p < .05). However, the final sprint and performance time in the high CHO or low CHO diets were statistically not significantly different from the normal CHO diet (13.8 ± 2.2 km·h⻹ and 50.9 ± 7.4 min; p > .05). CHO oxidation rate during the constant load exercise at 65% of VO2max was elevated in high CHO diet (1.05 ± 0.38 g·min⻹) compared with low CHO diet (0.63 ± 0.36 g·min⻹). The rating of perceived exertion increased linearly throughout the trial, independently of the dietary regimen. In conclusion, the high CHO diet induced higher CHO oxidation rates, increased running speed in the final 400 m and enhanced overall running performance, compared with low CHO.
Assuntos
Desempenho Atlético/fisiologia , Carboidratos da Dieta/administração & dosagem , Corrida/fisiologia , Adolescente , Estudos Cross-Over , Ingestão de Energia , Teste de Esforço , Frequência Cardíaca , Humanos , Masculino , Consumo de Oxigênio , Esforço Físico , Troca Gasosa PulmonarRESUMO
BACKGROUND: The endurance exercise is capable of inducing skeletal muscle, heart, and respiratory fatigue, evidenced by morphofunctional cardiac changes, release of myocardial injury biomarkers, and reduction of maximal voluntary ventilation and oxygen consumption (VO2) at peak exercise. PURPOSE: The aim of this study was to investigate whether marathoners present cardiac fatigue after marathon and whether it correlates with pulmonary levels of exhaled nitric oxide (eNO) and pulmonary inflammation. METHODS: 31 male marathoners, age 39 ± 9 years, were evaluated by cardiopulmonary exercise test three weeks before and between three and 15 days after a marathon; eNO analysis and spirometry were evaluated before, immediately after, and 24 and 72 hours after the marathon, and sputum cellularity and cytokine level were assessed before and after the marathon. RESULTS: Marathon induced an increase in the percentage of macrophages, neutrophils (from 0.65% to 4.28% and 6.79% to 14.11%, respectively), and epithelial cells and a decrease in cytokines in induced sputum, followed by an increase in eNO concentration (20 ± 11 to 35 ± 19 ppb), which presented a significant reduction 24 and 72 hours after marathon (9 ± 12 e 12 ± 9 ppb, p < 0.05). We observed a decrease in the spirometry parameters in all time points assessed after the marathon (p < 0.05) as well as in cardiopulmonary capacity, evidenced by a reduction in VO2 and ventilation peaks (57 ± 6 to 55 ± 6 mL·min-1·Kg-1 and 134 ± 19 to 132 ± 18 Lpm, respectively, p < 0.05). Finally, we observed a negative correlation between the decrease in forced expiratory volume and decrease in eNO 24 and 72 hours after marathon (r = -0.4, p = 0.05). CONCLUSION: Reduction in eNO bioavailability after marathon prevents the reduction in cardiopulmonary capacity induced by acute inflammatory pattern after marathon.
Assuntos
Teste de Esforço , Expiração , Óxido Nítrico/metabolismo , Corrida/fisiologia , Adulto , Citocinas/metabolismo , Humanos , Inflamação/patologia , Pulmão/patologia , Masculino , Escarro/metabolismoRESUMO
PURPOSE: This study aimed to determine the effect of preexercise metabolic acidosis and alkalosis on power output (PO) and aerobic and anaerobic energy expenditure during a 4-km cycling time trial (TT). METHODS: Eleven recreationally trained cyclists (VËO2peak 54.1 ± 9.3 mL·kg·min) performed a 4-km TT 100 min after ingesting in a double-blind matter 0.15 g·kg of body mass of ammonium chloride (NH4Cl, acidosis), 0.3 g·kg of sodium bicarbonate (NaHCO3, alkalosis), or 0.15 g·kg of CaCO3 (placebo). A preliminary study (n = 7) was conducted to establish the optimal doses to promote the desirable preexercise blood pH alterations without gastrointestinal distress. Data for PO, aerobic and anaerobic energy expenditure, and blood and respiratory parameters were averaged for each 1 km and compared between conditions using two-way repeated-measures ANOVA (condition and distance factors). Gastrointestinal discomfort was analyzed qualitatively. RESULTS: Compared with placebo (pH 7.37 ± 0.02, [HCO3]: 27.5 ± 2.6 mmol·L), the NaHCO3 ingestion resulted in a preexercise blood alkalosis (pH +0.06 ± 0.04, [HCO3]: +4.4 ± 2.0 mmol·L, P < 0.05), whereas NH4Cl resulted in a blood acidosis (pH -0.05 ± 0.03, [HCO3]: -4.8 ± 2.1 mmol·L, P < 0.05). Anaerobic energy expenditure rate and PO were reduced throughout the trial in NH4Cl compared with placebo and NaHCO3, resulting in a lower total anaerobic work and impaired performance (P < 0.05). Plasma lactate, VËCO2, and end-tidal CO2 partial pressure were lower and the VËE/VËCO2 higher throughout the trial in NH4Cl compared with placebo and NaHCO3 (P < 0.05). There was no difference between NaHCO3 and placebo for any of these variables (P > 0.05). Minimal gastrointestinal distress was noted in all conditions. CONCLUSION: Preexercise acidosis, but not alkalosis, affects anaerobic metabolism and PO during a 4-km cycling TT.
Assuntos
Acidose/fisiopatologia , Alcalose/fisiopatologia , Desempenho Atlético/fisiologia , Ciclismo/fisiologia , Metabolismo Energético/fisiologia , Acidose/complicações , Adulto , Alcalose/complicações , Cloreto de Alumínio , Compostos de Alumínio/sangue , Cloretos/sangue , Método Duplo-Cego , Gastroenteropatias/etiologia , Humanos , Concentração de Íons de Hidrogênio , Ácido Láctico/sangue , Masculino , Bicarbonato de Sódio/sangue , Fatores de TempoRESUMO
Previous studies have demonstrated the physiological changes induced by exercise exposure in hot environments. We investigated the hematological and oxidative changes and tissue damage induced by marathon race in different thermal conditions. Twenty-six male runners completed the São Paulo International Marathon both in hot environment (HE) and in temperate environment (TE). Blood and urine samples were collected 1 day before, immediately after, 1 day after, and 3 days after the marathon to analyze the hematological parameters, electrolytes, markers of tissue damage, and oxidative status. In both environments, the marathon race promotes fluid and electrolyte imbalance, hemolysis, oxidative stress, immune activation, and tissue damage. The marathon runner's performance was approximately 13.5% lower in HE compared to TE; however, in HE, our results demonstrated more pronounced fluid and electrolyte imbalance, renal damage, hemolysis, and immune activation. Moreover, oxidative stress induced by marathon in HE is presumed to be related to protein/purine oxidation instead of other oxidative sources. Fluid and electrolyte imbalance and protein/purine oxidation may be important factors responsible for hemolysis, renal damage, immune activation, and impaired performance after long-term exercise in HE. Nonetheless, we suggested that the impairment on performance in HE was not associated to the muscle damage and lipoperoxidation.
Assuntos
Eletrólitos/metabolismo , Hemólise/fisiologia , Temperatura Alta/efeitos adversos , Rim/patologia , Adulto , Humanos , Masculino , CorridaRESUMO
BACKGROUND: Prolonged aerobic exercise, such as running a marathon, produces supraphysiological stress that can affect the athlete's homeostasis. Some degree of transient myocardial dysfunction ("cardiac fatigue") can be observed for several days after the race. OBJECTIVE: To verify if there are changes in the cardiopulmonary capacity, and cardiac inotropy and lusitropy in amateur marathoners after running a marathon. METHODS: The sample comprised 6 male amateur runners. All of them underwent cardiopulmonary exercise testing (CPET) one week before the São Paulo Marathon, and 3 to 4 days after that race. They underwent echocardiography 24 hours prior to and immediately after the marathon. All subjects were instructed not to exercise, to maintain their regular diet, ingest the same usual amount of liquids, and rest at least 8 hours a day in the period preceding the CPET. RESULTS: The athletes completed the marathon in 221.5 (207; 250) minutes. In the post-marathon CPET, there was a significant reduction in peak oxygen consumption and peak oxygen pulse compared to the results obtained before the race (50.75 and 46.35 mL.kg-1 .min-1; 19.4 and 18.1 mL.btm, respectively). The echocardiography showed a significant reduction in the s' wave (inotropic marker), but no significant change in the E/e' ratio (lusitropic marker). CONCLUSIONS: In amateur runners, the marathon seems to promote changes in the cardiopulmonary capacity identified within 4 days after the race, with a reduction in the cardiac contractility. Such changes suggest that some degree of "cardiac fatigue" can occur.
Assuntos
Coração/fisiologia , Fadiga Muscular/fisiologia , Consumo de Oxigênio/fisiologia , Corrida/fisiologia , Adulto , Ecocardiografia , Teste de Esforço , Humanos , Masculino , Pessoa de Meia-Idade , Contração Miocárdica/fisiologia , Valores de Referência , Estatísticas não Paramétricas , Fatores de Tempo , Função VentricularRESUMO
The fatigue induced by marathon races was observed in terms of inflammatory and immunological outcomes. Neutrophil survival and activation are essential for inflammation resolution and contributes directly to the pathogenesis of many infectious and inflammatory conditions. The aim of this study was to investigate the effect of marathon races on surface molecules related to neutrophil adhesion and extrinsic apoptosis pathway and its association with inflammatory markers. We evaluated 23 trained male runners at the São Paulo International Marathon 2013. The following components were measured: hematological and inflammatory mediators, muscle damage markers, and neutrophil function. The marathon race induced an increased leukocyte and neutrophil counts; creatine kinase (CK), lactate dehydrogenase (LDH), CK-MB, interleukin (IL)-6, IL-10, and IL-8 levels. C-reactive protein (CRP), IL-12, and tumor necrosis factor (TNF)-α plasma concentrations were significantly higher 24 h and 72 h after the marathon race. Hemoglobin and hematocrit levels decreased 72 h after the marathon race. We also observed an increased intercellular adhesion molecule-1 (ICAM-1) expression and decreasedTNF receptor-1 (TNFR1) expression immediately after and 24 h after the marathon race. We observed an increased DNA fragmentation and L-selectin and Fas receptor expressions in the recovery period, indicating a possible slow rolling phase and delayed neutrophil activation and apoptosis. Marathon racing affects neutrophils adhesion and survival in the course of inflammation, supporting the "open-window" post-exercise hypothesis.
Assuntos
Antígenos de Superfície/sangue , Mediadores da Inflamação/sangue , Migração e Rolagem de Leucócitos , Ativação de Neutrófilo , Neutrófilos/metabolismo , Corrida , Adulto , Apoptose , Sobrevivência Celular , Citocinas/sangue , Humanos , Contagem de Leucócitos , MasculinoRESUMO
We analyzed the influence of prior exercise designed to reduce predominantly muscle glycogen in either type I or II fibers on pacing and performance during a 4-km cycling time trial (TT). After preliminary and familiarization trials, in a randomized, repeated-measures crossover design, ten amateur cyclists performed: 1) an exercise designed to reduce glycogen of type I muscle fibers, followed by a 4-km TT (EX-FIB I); 2) an exercise designed to reduce glycogen of type II muscle fibers, followed by a 4-km TT (EX-FIB II) and; 3) a 4-km TT, without the prior exercise (CONT). The muscle-glycogen-reducing exercise in both EX-FIB I and EX-FIB II was performed in the evening, â¼12 h before the 4-km TT. Performance time was increased and power output (PO) was reduced in EX-FIB I (432.8±8.3 s and 204.9±10.9 W) and EX-FIB II (428.7±6.7 s and 207.5±9.1 W) compared to CONT (420.8±6.4 s and 218.4±9.3 W; P<0.01), without a difference between EX-FIB I and EX-FIB II (P>0.05). The PO was lower in EX-FIB I than in CONT at the beginning and middle of the trial (P<0.05). The mean aerobic contribution during EX-FIB I was also significantly lower than in CONT (P<0.05), but there was no difference between CONT and EX-FIB II or between EX-FIB I and EX-FIB II (P>0.05). The integrated electromyography was unchanged between conditions (P>0.05). Performance may have been impaired in EX-FIB I due a more conservative pacing at the beginning and middle, which was associated with a reduced aerobic contribution. In turn, the PO profile adopted in EX-FIB II was also reduced throughout the trial, but the impairment in performance may be attributed to a reduced glycolytic contribution (i.e. reduced lactate accumulation).
Assuntos
Ciclismo/fisiologia , Metabolismo Energético , Exercício Físico/fisiologia , Adulto , Feminino , Glicogênio/metabolismo , Humanos , Ácido Láctico/sangue , Masculino , Contração Muscular , Músculos/metabolismo , Músculos/fisiologia , Fatores de TempoRESUMO
BACKGROUND: The endurance exercise is capable of inducing skeletal muscle, heart, and respiratory fatigue, evidenced by morpho functional cardiac changes, release of myocardial injury biomarkers, and reduction of maximal voluntary ventilation and oxygen consumption (VO2) at peak exercise. PURPOSE: The aim of this study was to investigate whether marathoners present cardiac fatigue after marathon and whether it correlates with pulmonary levels of exhaled nitric oxide (Eno) and pulmonary inflammation. METHODS: 31 male marathoners, age 39 ± 9 years, were evaluated by cardiopulmonary exercise test three weeks before and between three and 15 days after a marathon; Eno analysis and spirometry were evaluated before, immediately after, and 24 and 72 hours after the marathon, and sputum cellularity and cytokine level were assessed before and after the marathon. RESULTS: Marathon induced an increase in the percentage of macrophages, neutrophils (from 0.65% to 4.28% and 6.79% to 14.11%, respectively), and epithelial cells and a decrease in cytokines in induced sputum, followed by an increase in Eno concentration (20 ± 11 to 35 ± 19 ppb), which presented a significant reduction 24 and 72 hours after marathon (9 ± 12 e 12 ± 9 ppb, p < 0.05). We observed a decrease in the spirometry parameters in all time points assessed after the marathon (p < 0.05) as well as in cardiopulmonary capacity, evidenced by a reduction in VO2 and ventilation peaks (57 ± 6 to 55 ± 6 mL·min-1·Kg-1 and 134 ± 19 to 132 ± 18 Lpm, respectively, p < 0.05). Finally, we observed a negative correlation between the decrease in forced expiratory volume and decrease in Eno 24 and 72 hours after marathon (r = -0.4, p = 0.05). CONCLUSION: Reduction in Eno bioavailability after marathon prevents the reduction in cardiopulmonary capacity induced by acute inflammatory pattern after marathon. (AU)
Assuntos
Humanos , Adulto , Corrida/fisiologia , Escarro/metabolismo , Citocininas , Expiração , Teste de Esforço , Inflamação/patologiaRESUMO
The purpose of the present study was to investigate the effects of caffeine ingestion on pacing strategy and energy expenditure during a 4000-m cycling time-trial (TT). Eight recreationally-trained male cyclists volunteered and performed a maximal incremental test and a familiarization test on their first and second visits, respectively. On the third and fourth visits, the participants performed a 4000-m cycling TT after ingesting capsules containing either caffeine (5 mg.kg(-1) of body weight, CAF) or cellulose (PLA). The tests were applied in a double-blind, randomized, repeated-measures, cross-over design. When compared to PLA, CAF ingestion increased mean power output [219.1±18.6 vs. 232.8±21.4 W; effect size (ES) â=â0.60 (95% CIâ=â0.05 to 1.16), pâ=â0.034] and reduced the total time [419±13 vs. 409±12 s; ESâ=â-0.71 (95% CIâ=â-0.09 to -1.13), pâ=â0.026]. Furthermore, anaerobic contribution during the 2200-, 2400-, and 2600-m intervals was significantly greater in CAF than in PLA (p<0.05). However, the mean anaerobic [64.9±20.1 vs. 57.3±17.5 W] and aerobic [167.9±4.3 vs. 161.8±11.2 W] contributions were similar between conditions (p>0.05). Similarly, there were no significant differences between CAF and PLA for anaerobic work (26363±7361 vs. 23888±6795 J), aerobic work (68709±2118 vs. 67739±3912 J), or total work (95245±8593 vs. 91789±7709 J), respectively. There was no difference for integrated electromyography, blood lactate concentration, heart rate, and ratings of perceived exertion between the conditions. These results suggest that caffeine increases the anaerobic contribution in the middle of the time trial, resulting in enhanced overall performance.
Assuntos
Limiar Anaeróbio/efeitos dos fármacos , Cafeína/farmacologia , Estimulantes do Sistema Nervoso Central/farmacologia , Exercício Físico/fisiologia , Adulto , Estudos Cross-Over , Eletromiografia , Frequência Cardíaca/efeitos dos fármacos , Humanos , Masculino , Fatores de TempoRESUMO
ABSTRACT The relationship between metabolic acidosis and athletic performance has been investigated over the years through manipulation of the blood and muscle pH. Among the pH manipulation manners, the ammonium chloride (NH4Cl) is the most widely used chemical component when is intentioned to induce a blood acidosis status prior to exercise. However, there is a lack of studies investigating the action of this substance on athletic performance as only two studies were performed in the last 15 years. Thus, it will be addressed in the present review the main aspects involved in NH4Cl ingestion, giving a focus to the action mechanisms of this substance, specifications about the used dose and their effects on athletic performance.
RESUMO A relação entre a acidose metabólica e o desempenho esportivo tem sido investigada ao longo dos anos através de manipulações do pH sanguíneo e muscular. Entre as formas de manipulação do pH, o cloreto de amônio (NH4Cl) é o componente químico mais utilizado quando se pretende induzir um estado de acidose sanguínea previamente ao exercício. Entretanto, investigações acerca da ação desse agente sobre o desempenho esportivo ainda podem ser consideradas escassas, quando foram realizados apenas dois estudos nos últimos 15 anos. Dessa forma, serão abordados na presente revisão os principais aspectos envolvidos na ingestão de NH4Cl, dando um enfoque aos mecanismos de ação dessa substância, especificações acerca do tipo de dose utilizada e seus efeitos sobre o desempenho esportivo.
Assuntos
Acidose , Desempenho Atlético , Cloreto de AmônioRESUMO
Previous studies have demonstrated the physiological changes induced by exercise exposure in hot environments. We investigated the hematological and oxidative changes and tissue damage induced by marathon race in different thermal conditions. Twenty-six male runners completed the São Paulo International Marathon both in hot environment (HE) and in temperate environment (TE). Blood and urine samples were collected 1 day before, immediately after, 1 day after, and 3 days after the marathon to analyze the hematological parameters, electrolytes, markers of tissue damage, and oxidative status. In both environments, the marathon race promotes fluid and electrolyte imbalance, hemolysis, oxidative stress, immune activation, and tissue damage. The marathon runner's performance was approximately 13.5% lower in HE compared to TE; however, in HE, our results demonstrated more pronounced fluid and electrolyte imbalance, renal damage, hemolysis, and immune activation. Moreover, oxidative stress induced by marathon in HE is presumed to be related to protein/purine oxidation instead of other oxidative sources. Fluid and electrolyte imbalance and protein/purine oxidation may be important factors responsible for hemolysis, renal damage, immune activation, and impaired performance after long-term exercise in HE. Nonetheless, we suggested that the impairment on performance in HE was not associated to the muscle damage and lipoperoxidation.
Assuntos
Animais , Masculino , Corrida , Eletrólitos/metabolismo , Hemólise/fisiologia , Rim/patologiaRESUMO
Abstract Background: Prolonged aerobic exercise, such as running a marathon, produces supraphysiological stress that can affect the athlete's homeostasis. Some degree of transient myocardial dysfunction ("cardiac fatigue") can be observed for several days after the race. Objective: To verify if there are changes in the cardiopulmonary capacity, and cardiac inotropy and lusitropy in amateur marathoners after running a marathon. Methods: The sample comprised 6 male amateur runners. All of them underwent cardiopulmonary exercise testing (CPET) one week before the São Paulo Marathon, and 3 to 4 days after that race. They underwent echocardiography 24 hours prior to and immediately after the marathon. All subjects were instructed not to exercise, to maintain their regular diet, ingest the same usual amount of liquids, and rest at least 8 hours a day in the period preceding the CPET. Results: The athletes completed the marathon in 221.5 (207; 250) minutes. In the post-marathon CPET, there was a significant reduction in peak oxygen consumption and peak oxygen pulse compared to the results obtained before the race (50.75 and 46.35 mL.kg-1 .min-1; 19.4 and 18.1 mL.btm, respectively). The echocardiography showed a significant reduction in the s' wave (inotropic marker), but no significant change in the E/e' ratio (lusitropic marker). Conclusions: In amateur runners, the marathon seems to promote changes in the cardiopulmonary capacity identified within 4 days after the race, with a reduction in the cardiac contractility. Such changes suggest that some degree of "cardiac fatigue" can occur.
Resumo Fundamento: O exercício aeróbico prolongado, como correr uma maratona, produz um estresse suprafisiológico que pode ter impacto na homeostase do atleta. Algum grau de disfunção miocárdica transitória ("fadiga cardíaca") pode ser observado ao longo de vários dias após a prova. Objetivos: Verificar se ocorrem alterações na capacidade cardiopulmonar, no inotropismo e no lusitropismo cardíaco de maratonistas amadores após a realização de uma maratona. Métodos: A amostra foi composta por 6 corredores amadores masculinos. Todos realizaram teste cardiopulmonar de exercício (TCPE) uma semana antes da Maratona de São Paulo e 3 a 4 dias após a mesma. Realizaram ecocardiograma 24 horas antes e imediatamente após a prova. Todos foram orientados a não se exercitar, manter dieta regular, ingerir a mesma quantidade habitual de líquidos e descansar pelo menos 8 horas ao dia no período anterior ao TCPE. Resultados: Os atletas completaram a maratona em 221,5 (207; 250) minutos. No TCPE pós-maratona, ocorreu redução significativa no consumo de oxigênio e no pulso de oxigênio de pico em relação àqueles obtidos antes da prova (50,75 e 46,35 ml.kg-1.min-1; 19,4 e 18,1 ml.btm, respectivamente). Ao ecocardiograma, encontramos redução significativa na onda s' (marcador do inotropismo). A relação E/e' não apresentou alteração significativa após a maratona (marcador do lusitropismo). Conclusões: Em atletas amadores, a maratona parece promover alterações na capacidade cardiopulmonar identificadas pelo menos em até 4 dias após a prova, com redução na contratilidade e, portanto, no inotropismo cardíaco. Tais modificações sugerem que algum grau de "fadiga cardíaca" possa ocorrer.
Assuntos
Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Coração/fisiologia , Fadiga Muscular/fisiologia , Consumo de Oxigênio/fisiologia , Corrida/fisiologia , Ecocardiografia , Teste de Esforço , Contração Miocárdica/fisiologia , Valores de Referência , Estatísticas não Paramétricas , Fatores de Tempo , Função VentricularRESUMO
The fatigue induced by marathon races was observed in terms of inflammatory and immunological outcomes. Neutrophil survival and activation are essential for inflammation resolutionand contributes directly to the pathogenesis of many infectious and inflammatory conditions.nThe aim of this study was to investigate the effect of marathon races on surface moleculesrelated to neutrophil adhesion and extrinsic apoptosis pathway and its association with inflammatory markers. We evaluated 23 trained male runners at the São Paulo International Marathon 2013. The following components were measured: hematological and inflammatory mediators, muscle damage markers, and neutrophil function. The marathon raceinduced an increased leukocyte and neutrophil counts; creatine kinase (CK), lactate dehydrogenase(LDH), CK-MB, interleukin (IL)-6, IL-10, and IL-8 levels. C-reactive protein(CRP), IL-12, and tumor necrosis factor (TNF)-α plasma concentrations were significantlyhigher 24 h and 72 h after the marathon race. Hemoglobin and hematocrit levels decreased72 h after the marathon race. We also observed an increased intercellular adhesion molecule-1(ICAM-1) expression and decreasedTNF receptor-1 (TNFR1) expression immediatelyafter and 24 h after the marathon race. We observed an increased DNA fragmentation and L-selectin and Fas receptor expressions in the recovery period, indicating a possibleslow rolling phase and delayed neutrophil activation and apoptosis. Marathon racing affectsneutrophils adhesion and survival in the course of inflammation, supporting the openwindowpost-exercise hypothesis...
Assuntos
Doenças Transmissíveis , NeutrófilosRESUMO
INTRODUÇÃO: Apesar de a prática regular de exercício físico reduzir o risco de doença cardiovascular, estudos recentes têm documentado elevações em biomarcadores relacionados com danos cardíacos após exercícios prolongados em indivíduos aparentemente saudáveis. OBJETIVO: Investigar as alterações nos níveis de brain natriuretic peptide (BNP) e troponina T cardíaca (cTnT) em atletas amadores após uma maratona, assim como verificar as possíveis relações entre as alterações, antes e depois da prova, apresentada pelos dois biomarcadores e variáveis do teste cardiopulmonar. MÉTODOS: Estudamos 38 atletas do sexo masculino (40,9 ± 6,29 anos) antes e depois da Maratona Internacional de São Paulo, SP, Brasil. Foram realizadas coletas de sangue na veia antecubital para mensurar os biomarcadores cardíacos, cTnT e BNP 24h antes, imediatamente após e 24h após a maratona. Foi realizado teste cardiopulmonar máximo nas três semanas que antecederam a prova. RESULTADOS: Os valores de BNP e cTnT aumentaram imediatamente após a maratona (p<0,001) quando comparados com os valores basais. No terceiro momento (24h) os valores de troponina tiveram uma redução significativa caracterizando um retorno aos valores basais. Não encontramos correlação entre idade e variáveis referentes a intensidade da maratona, porém encontramos correlação dos biomarcadores com o tempo de conclusão da maratona. CONCLUSÃO: Diferentes causas de liberação podem ser assumidas para cTnT e BNP e, neste caso, parecem não refletir dano miocárdico devido ao comportamento da curva destes marcadores, além de não haver relação entre a liberação dos dois biomarcadores. .
INTRODUCTION: Although the practice of physical exercises reduces the cardiovascular risk, recent studies have documented elevations in cardiac injury biomarkers after prolonged exercises in apparently healthy individuals. OBJECTIVE: We aimed to investigate the changes in brain natriuretic peptide (BNP) and cardiac troponin T (cTnT) levels after a marathon, and the correlation of these biomarkers and the variables of cardiopulmonary test. METHODS: We studied 38 male athletes (40.9 ± 6.29 years old) participants at the São Paulo International Marathon, SP, Brasil. Blood collections were performed to measure cTnT and BNP 24h before, immediately after and 24h after the marathon. Cardiopulmonary test was performed in the three weeks preceding the marathon. RESULTS: BNP and cTnT values increased significantly after the marathon (p<0.001). In the third moment (24h) the troponin values returned to the baseline values. We found no correlation between age and variables of the marathon, however, we did find a correlation between the biomarkers and time to complete the marathon. CONCLUSION: Various causes of release may be presumed for cTnT and BNP, however, they do not seem to reflect into myocardial injury, and there is no relationship between the releases of the two biomarkers. .
INTRODUCCIÓN: A pesar de que la práctica regular de ejercicio reduce el riesgo de enfermedad cardiovascular, estudios recientes han documentado elevaciones en biomarcadores relacionados con daños cardiacos después de ejercicios prolongados en individuos aparentemente saludables. OBJETIVO: Investigar las alteraciones en los niveles de BNP y troponina T cardiaca (cTnT) en atletas amateur después de maratón, así como verificar las posibles relaciones entre las alteraciones, antes y después de la prueba, presentada por dos biomarcadores y variables del test cardiopulmonar. MÉTODOS: Estudiamos 38 atletas del sexo masculino (40,9±6,29 años) antes y después de la Maratón Internacional de São Paulo, SP, Brasil. Fueron realizadas colectas de sangre en la vena antecubital para medir los biomarcadores cardiacos, cTnT y BNP, 24 horas antes, inmediatamente y 24 horas después de la Maratón. Fue realizado test cardiopulmonar máximo en las tres semanas que antecedieron a la maratón. RESULTADOS: Los valores de BNP y cTnT aumentaron inmediatamente después de la maratón (p<0,001) cuando comparados con los valores basales. En el tercer momento (24h) los valores de troponina tuvieron una reducción significativa caracterizando un retorno a los valores basales. No encontramos correlación entre edad y variables referentes a intensidad de la maratón, sin embargo encontramos correlación de los biomarcadores con el tiempo de conclusión de la maratón. CONCLUSIÓN: Diferentes causas de liberación pueden ser asumidas para cTnT y BNP y, en este caso, parecen no reflejar daño miocárdico debido al comportamiento de la curva de estos marcadores, además de no haber relación entre la liberación de los dos biomarcadores. .
RESUMO
RESUMO A escolha do pacing é determinante para o sucesso esportivo, mas a análise de pequenas alterações no pacing necessita de mais estudos. O objetivo deste estudo foi determinar parâmetros na curva de desempenho em contrarrelógio de ciclismo para investigar variações dopacing e sua reprodutibilidade. A análise por trechos da prova também foi realizada. 19 ciclistas amadores realizaram dois testes de 4-km, no qual foram analisados parâmetros nas curvas de desempenho individuais e a potência média dos trechos da prova. O tempo e a potência média foram similares entre os testes. Não houve diferença entre os parâmetros observados na curva de desempenho comparando o teste 1 e 2, mas estes mostraram alto valor de erro típico da medida. A análise por trechos da prova foi mais consistente, sendo uma opção para analisar o pacing. Apesar de um desempenho consistente no contrarrelógio de 4-km, os parâmetros determinados apresentaram grande variação intraindividual.
ABSTRACT The selection of pacing is determinant for the sport success, but the analysis of modest variations in pacing requires further studies. The purpose of this study was to determine parameters in the performance curve on cycling time trial to investigate pacing variations and reproducibility. The test sections analysis was also performed. 19 amateur cyclists performed two tests of 4-km, in which parameters were analyzed in the individual performance curves and the average power of the test sections. The time and the average power were similar between tests. There was no difference between the parameters observed in the performance curve comparing the test 1 and 2, but these showed a high value of typical error. The test portions analysis was more consistent, with an alternative to analyze pacing. Despite consistent performance in time trial 4-km, the parameters determined varied widely between individuals.
RESUMO
The present study cross-sectionally investigated the influence of training status, route difficulty and upper body aerobic and anaerobic performance of climbers on the energetics of indoor rock climbing. Six elite climbers (EC) and seven recreational climbers (RC) were submitted to the following laboratory tests: (a) anthropometry, (b) upper body aerobic power, and (c) upper body Wingate test. On another occasion, EC subjects climbed an easy, a moderate, and a difficult route, whereas RC subjects climbed only the easy route. The fractions of the aerobic (W(AER)), anaerobic alactic (W(PCR)) and anaerobic lactic (W[La(-)]) systems were calculated based on oxygen uptake, the fast component of excess post-exercise oxygen uptake, and changes in net blood lactate, respectively. On the easy route, the metabolic cost was significantly lower in EC [40.3 (6.5) kJ] than in RC [60.1 (8.8) kJ] (P < 0.05). The respective contributions of the W (AER), W (PCR), and W[La(-)] systems in EC were: easy route = 41.5 (8.1), 41.1 (11.4) and 17.4% (5.4), moderate route = 45.8 (8.4), 34.6 (7.1) and 21.9% (6.3), and difficult route = 41.9 (7.4), 35.8 (6.7) and 22.3% (7.2). The contributions of the W (AER), W (PCR), and W[La(-)] systems in RC subjects climbing an easy route were 39.7 (5.0), 34.0 (5.8), and 26.3% (3.8), respectively. These results indicate that the main energy systems required during indoor rock climbing are the aerobic and anaerobic alactic systems. In addition, climbing economy seems to be more important for the performance of these athletes than improved energy metabolism.
Assuntos
Metabolismo Energético , Montanhismo/fisiologia , Consumo de Oxigênio/fisiologia , Adulto , Exercício Físico/fisiologia , Humanos , Masculino , Resistência FísicaRESUMO
O objetivo do presente estudo foi investigar a contribuição dos parâmetros biomecânicos para o desempenho do salto vertical com contramovimento (SV) e SV precedido de corrida (SVcorrida) em 19 jogadoras da seleção brasileira adulta de basquetebol feminino (26,2 ± 4,7 anos; 1,81 ± 0,07 m; 75,6 ± 12,6 kg; 20,4 ± 6,0% de gordura). Foram considerados os picos de força passiva (PFPa) e propulsão (PFP), tempo para alcance dos picos de força passiva (TPFPa) e propulsão (TPFP), "load rate" (LR), taxa de desenvolvimento de força (TDF), tempo de fase excêntrica (Texc) e concêntrica (Tcon). A análise de componentes principais revelou que 50,86% da altura de SV foi explicada por PFPa, TPFPa, LR, Texc e TPFP, e que 43,28% de SVcorrida foi explicada por PFPa, TPFPa, LR, PFP. Esses resultados sugerem que parâmetros temporais parecem contribuir de maneira mais significativa para o desempenho de salto, porém diferentes tipos de salto podem demandar comportamentos distintos de parâmetros biomecânicos.
The aim of the study was to investigate the contribution of biomechanics parameters to counter-movement jump (CMJ) and CMJ preceded by run (CMJrun) in nineteen female basketball players from Brazilian National Team (26.2 ± 4.7 years; 1.81 ± 0.07 m; 75.6 ± 12.6 kg; 20.4 ± 6.0 % body fat). The parameters analyzed were passive (PaPF) and propulsion peak force (PPF), time to passive (TPaPF) and propulsion peak force (TPPF), load rate (LR), rate of force development (RFD), eccentric (Texc) and concentric phase duration (Texc). The principal component analysis showed that 50.86% of CMJ performance was explained by PaPF, TPaPF, LR, Texc and TPPF, and 43.28% of CMJrun was explained by PaPF, TPaPF, LR and PPF. These findings suggest that temporal parameters appear to have greater contribution to jump performance. Moreover, different types of jumps appear to induce distinct behavior of biomechanics parameters.
El objetivo de este estudio fue investigar la contribución de parámetros biomecánicos para el rendimiento de salto vertical con contra movimiento (SV) e SV precedido de carrera (SVcarrera) en diecinueve jugadoras de baloncesto de la selección brasileña femenina adultas (26,2 ± 4,7 años; 1,81 ± 0,07 m; 75,6 ± 12,6 kg; 20,4 ± 6,0% de grasa). Fueran considerados el pico de fuerza pasiva (PFPa) y propulsión (PFP), tiempo para llegar a picos de fuerza pasiva (TPFPa) y propulsión (TPFP), la tasa de carga (LR), tasa de desarrollo de fuerza (TDF), tiempo de la fase excéntrica (Texc) y concéntrica (Tcon). Las análisis de los componentes principales mostraron que 50,86% da la altura de SV fue explicada por PFPa, TPFPa, LR, Texc y TPFP, y que 43,28% de SVcarrera fue explicada por PFPa, TPFPa, LR, PFP. Los resultados sugieren parámetros temporales parecen contribuir más significativamente para rendimiento del salto pero, diferentes tipos del salto pueden demandar comportamientos distintos de los parámetros biomecánicos.
Assuntos
Humanos , Feminino , Adulto , Desempenho Atlético , Basquetebol , Fenômenos BiomecânicosRESUMO
Esse trabalho comparou a variabilidade da frequência cardíaca (VFC) de repouso antes e após 10 semanas de treinamento de força de grupos que usaram e não usaram a plataforma vibratória. Dezessete homens saudáveis foram divididos nos grupos treinamento de força convencional (TF) ou treinamento de força sobre a plataforma vibratória a frequência de 30 Hz (TF+V30). As mensurações do desempenho de força dinâmica máxima (1-RM) no exercício meio agachamento e da VFC de repouso foram feitas antes e após o programa de treinamento. Ambos os grupos tiveram aumento significante da força no período pós (de 15,1% no grupo TF e de 16,4% no grupo TF+V30), no entanto esse aumento se alterou na mesma magnitude para os dois grupos, não havendo diferença entre eles no desempenho de 1-RM nos períodos pré e pós-treinamento. Não foi observada diferença nas comparações entre os grupos e nas situações pré e pós-treinamento nas análises da VFC de repouso, no entanto a magnitude do effect size foi moderada (ES = 0,50-0,80) para algumas variáveis (intervalo R-R, desvio-padrão da média de todos os intervalos R-R - SDNN, raiz quadrada da média dos quadrados das diferenças entre os intervalos R-R sucessivos - RMSSD, componente de baixa frequência ajustada por meio de logarítmico - InLF e componente de alta frequência ajustada por meio de logarítmico - InHF) no grupo TF+V30 após o período de treinamento. Conclui-se que 10 semanas de treinamento de força com e sem a presença da vibração proporcionou aumento semelhante no desempenho de 1-RM em ambos os grupos e, embora o estímulo adicional da vibração tenha dado indícios de maior atividade vagal analisado por meio do ES, nenhum dos grupos apresentou alteração significante da VFC.
The current research compared resting heart rate variability (VFC) before and after 10 weeks of strength training in groups that used and did not use a vibration platform. Seventeen healthy men were divided into conventional strength training (TF) or strength training using a vibration platform with a frequency of 30 Hz (TF+V30) training groups. One repetition maximum load (1-RM) on half squat exercise and VFC measurements were determined pre- and post-training program. Both groups had improved 1-RM load after the program (15.1% in TF group and 16.4% in TF+V30 group), although this increase was changed in the same extent for the two groups and there was no difference in 1-RM load between groups pre- and post-training program. No significant difference was observed in resting VFC measurements between groups pre and post-training program, however the magnitude of the effect size was moderated (ES = 0.50-0.80) for some variables (R-R interval, standard deviation of all R-R interval - SDNN, RMSSD, log-transformed of low frequency - InLF, and log-transformed of high frequency - InHF) in TF+V30 group. It was concluded that 10 weeks of strength training program with or without the vibration platform provided similar increase in 1-RM load in both groups, and although some evidences in this study indicate that vibration can increase vagal activity analyzed by ES, in neither groups the strength training was able to change VFC significantly.
Assuntos
Humanos , Masculino , Adulto , Sistema Nervoso Autônomo , Frequência Cardíaca/fisiologia , Força Muscular , VibraçãoRESUMO
O Modelo de Equilíbrio Dinâmico (MED) assume a existência de uma intensidade máxima de exercício na qual seja possível observar um estado de equilíbrio fisiológico, o qual assegura o prolongamento do exercício. Até esta intensidade limite o exercício seria limitado pelos estoques de glicogênio muscular, mas acima desta, o acúmulo de metabólitos causaria a falha dos sistemas corporais e o término do exercício seria coincidente com o alcance de valores máximos em variáveis fisiológicas. Entretanto, o MED não se ajusta inteiramente aos resultados experimentais, pois estudos falharam em demonstrar um completo equilíbrio fisiológico em cargas iguais ou inferiores a esta intensidade limite. Adicionalmente, evidências mostram que nesta mesma faixa de intensidade, o término do exercício ocorre sem haver completa depleção nos estoques de glicogênio muscular. Inicialmente, o desalinhamento entre teoria e dados experimentais poderia ser devido, ao menos em parte, a um aspecto metodológico comum entre estudos anteriores: a ausência do término do exercício identificado na incapacidade da manutenção de uma potência mecânica requerida. A ausência do ponto de exaustão como critério do término do exercício pode ter gerado um artefato temporal nas medidas realizadas, não garantindo que cada medida temporal representasse a mesma fase de ajuste fisiológico ao exercício. Contudo estudos recentes do nosso grupo sugerem outra perspectiva para interpretação dos dados experimentais; a existência de equilíbrio fisiológico regulado pelos sistemas nervoso central e periférico, numa ampla faixa de intensidade de exercício.
The Dynamic Equilibrium Model (DEM) assumes the presence of a maximal exercise intensity at which a complete physiological steady state occurs, allowing the exercise to be prolonged. Up to this limit of intensity, the exercise would be limited by muscle glycogen storages, but above this the metabolic accumulation would lead to a bodily systems failure that would match with maximal values in physiological variables. However, the DEM does not agree with experimental results, because studies have failed to demonstrate a full physiological steady state during exercise at or below this limit of intensity. Additionally, evidences have shown that exercise terminates without complete muscle glycogen depletion within this intensity range. Initially, the disagreement between theory and experimental data could be due partially to a methodological aspect: the absence of exercise termination determined by the incapacity for maintaining a required power output. Such absence of an exhaustion point as criteria to establish the exercise termination could have caused a temporal artifact, not allowing that each temporal measure has indicated the same phase of physiological adjustment to the effort. Yet, recent findings of our group have suggested another perspective to interpret the experimental data; the existence of physiological steady state regulated by the central and peripheral nervous system within a broad exercise intensity range.
Assuntos
Humanos , Esforço Físico/fisiologia , Exercício Físico/fisiologia , Fadiga Muscular/fisiologia , Homeostase/fisiologia , Glicogênio/fisiologiaRESUMO
Este estudo examinou a influência da cinética on do consumo de oxigênio (O2) sobre a estratégia de corrida adotada durante uma corrida de 10km em corredores com diferentes níveis de desempenho. Vinte e um corredores (28,5 ± 5,3 anos; 172,6 ± 7,3cm; 66,3 ± 9,3kg) realizaram: 1) um teste com incrementos de 1,2km.h-1 a cada três min até a exaustão; 2) um teste de seis minutos de velocidade constante a 9km.h-1 para identificar a cinética do O2; e 3) uma simulação de prova de 10km. Os sujeitos foram divididos em moderada (MP) e baixa (BP) performance de acordo com o tempo gasto para completar a prova de 10km. A velocidade média (MP = 16,9 ± 0,8 vs. BP = 14,9 ± 1km.h-1) na prova de 10km diferenciou significativamente (p < 0,05) entre os grupos. Não foram encontradas diferenças (p > 0,05) entre os grupos em nenhum dos parâmetros cinéticos analisados. Entretanto, a amplitude de aumento do O2 (parâmetro A1) foi inversamente correlacionado com a velocidade média (r = -0,48, p < 0,05) e com as parciais de velocidade na prova (r entre -0,44 e -0,48, p < 0,05), exceto no último trecho (r = -0,19, p > 0,05). Em conclusão, a cinética do O2 parece não interferir na estratégia de corrida adotada em grupos de corredores com diferentes níveis de performance. Contudo, a correlação do parâmetro A1 com as parciais de velocidade sugere uma influência da economia de corrida sobre a estratégia adotada durante a prova de 10km.
This study examined the influence of the O2 kinetics on the running strategy adopted during a 10km running race in runners with different performance levels. Twenty-one runners (28.5 ± 5.3 years; 17.6 ± 7.3 cm; 66.3 ± 9.3 kg) performed 1) a test with increments of 1.2 km.h-1 every 3 min until exhaustion; 2) one 6-min test of constant velocity at 9 km.h-1 for determination of O2 kinetics and; 3) a 10 km time trial simulation. The subjects were divided into two groups, Moderated Performance (MP) and Low Perfomance (LP), based on the 10-km running performance. Mean velocity (MP= 16.9 ± 0.8 vs BP= 14.9 ± 1 km.h-1) on the 10km race was significantly different (p<0.05) between groups. There were no differences (p>0.05) between groups in any kinetics parameters analyzed. However, the O2 increase amplitude (A1 parameter) was inversely correlated with mean velocity (r= -0.48, p < 0.05) and with the partial velocities on time trial (r between -0.44 and -0.48, p < 0.05), except for the last session (r=-0.19, p > 0.05). In conclusion, the correlation of A1 parameter with the partial velocities suggests an influence of running economy on the strategy adopted during the 10 km time trial.