Detalhe da pesquisa
1.
Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility.
Nat Chem Biol
; 20(3): 333-343, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-37735239
2.
In vivo base editing of a pathogenic Eif2b5 variant improves vanishing white matter phenotypes in mice.
Mol Ther
; 32(5): 1328-1343, 2024 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38454603
3.
Introducing gene deletions by mouse zygote electroporation of Cas12a/Cpf1.
Transgenic Res
; 28(5-6): 525-535, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31482512
4.
Enhancing prime editor activity by directed protein evolution in yeast.
Nat Commun
; 15(1): 2092, 2024 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38453904
5.
Predicting prime editing efficiency and product purity by deep learning.
Nat Biotechnol
; 41(8): 1151-1159, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36646933
6.
Recursive Editing improves homology-directed repair through retargeting of undesired outcomes.
Nat Commun
; 13(1): 4550, 2022 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35931681
7.
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.
Nat Biotechnol
; 39(8): 949-957, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34012094
8.
Preparation and electroporation of Cas12a/Cpf1-guide RNA complexes for introducing large gene deletions in mouse embryonic stem cells.
Methods Enzymol
; 616: 241-263, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30691645