Detalhe da pesquisa
1.
Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes.
J Neurosci
; 43(26): 4755-4774, 2023 06 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37286354
2.
Coronaviral RNA-methyltransferases: function, structure and inhibition.
Nucleic Acids Res
; 50(2): 635-650, 2022 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35018474
3.
Properties of water and argon clusters developed in supersonic expansions.
J Chem Phys
; 159(12)2023 Sep 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38127374
4.
Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold.
Bioorg Med Chem Lett
; 76: 129010, 2022 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36184029
5.
Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites.
PLoS Pathog
; 15(8): e1007962, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31381608
6.
Structural analysis of the putative SARS-CoV-2 primase complex.
J Struct Biol
; 211(2): 107548, 2020 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32535228
7.
Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses.
Arch Virol
; 165(2): 355-366, 2020 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-31845156
8.
Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation.
J Struct Biol
; 208(2): 92-98, 2019 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31415898
9.
Structural analysis of phosphatidylinositol 4-kinase IIIß (PI4KB) - 14-3-3 protein complex reveals internal flexibility and explains 14-3-3 mediated protection from degradation in vitro.
J Struct Biol
; 200(1): 36-44, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28864297
10.
The crystal structure of the phosphatidylinositol 4-kinase IIα.
EMBO Rep
; 15(10): 1085-92, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25168678
11.
The high-resolution crystal structure of phosphatidylinositol 4-kinase IIß and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 7): 1555-63, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-26143926
12.
Norbornane-based nucleoside and nucleotide analogues locked in North conformation.
Bioorg Med Chem
; 23(1): 184-91, 2015 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25435471
13.
Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase.
Structure
; 2024 May 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38781970
14.
Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.
Structure
; 32(4): 433-439.e4, 2024 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38325369
15.
Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors.
bioRxiv
; 2024 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37873443
16.
Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Antiviral Res
; 216: 105663, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37421984
17.
Does the Sign of Charge Affect the Surface Affinity of Simple Ions?
J Phys Chem B
; 127(27): 6205-6216, 2023 Jul 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37399285
18.
Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport.
Cells
; 12(15)2023 07 31.
Artigo
Inglês
| MEDLINE | ID: mdl-37566053
19.
Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase.
Nat Commun
; 14(1): 2259, 2023 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37080993
20.
SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses.
Biochim Biophys Acta Gen Subj
; 1867(4): 130319, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36764586