Detalhe da pesquisa
1.
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice.
Proc Natl Acad Sci U S A
; 112(45): 14078-83, 2015 Nov 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26508634
2.
Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long-Term Potentiation at SC-CA1 Synapses in the Hippocampus.
J Neurosci
; 35(19): 7600-15, 2015 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-25972184
3.
Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7.
ACS Chem Neurosci
; 5(12): 1221-37, 2014 Dec 17.
Artigo
Inglês
| MEDLINE | ID: mdl-25225882
4.
Norepinephrine transporter variant A457P knock-in mice display key features of human postural orthostatic tachycardia syndrome.
Dis Model Mech
; 6(4): 1001-11, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23580201
5.
Targeting selective activation of M(1) for the treatment of Alzheimer's disease: further chemical optimization and pharmacological characterization of the M(1) positive allosteric modulator ML169.
ACS Chem Neurosci
; 3(11): 884-95, 2012 Nov 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23173069