Detalhe da pesquisa
1.
NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.
PLoS Biol
; 18(11): e3000885, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33170835
2.
From single drug targets to synergistic network pharmacology in ischemic stroke.
Proc Natl Acad Sci U S A
; 116(14): 7129-7136, 2019 04 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30894481
3.
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.
Proc Natl Acad Sci U S A
; 114(46): 12315-12320, 2017 11 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29087944
4.
The NOX toolbox: validating the role of NADPH oxidases in physiology and disease.
Cell Mol Life Sci
; 69(14): 2327-43, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22648375
5.
Endothelial reactive oxygen-forming NADPH oxidase 5 is a possible player in diabetic aortic aneurysm but not atherosclerosis.
Sci Rep
; 12(1): 11570, 2022 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35798762
6.
VAS2870 is a pan-NADPH oxidase inhibitor.
Cell Mol Life Sci
; 69(18): 3159-60, 2012 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-22875281
7.
A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection.
NPJ Syst Biol Appl
; 4: 8, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29423274
8.
NOS knockout or inhibition but not disrupting PSD-95-NOS interaction protect against ischemic brain damage.
J Cereb Blood Flow Metab
; 36(9): 1508-12, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27354091
9.
Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement.
Antioxid Redox Signal
; 23(5): 406-27, 2015 Aug 10.
Artigo
Inglês
| MEDLINE | ID: mdl-24383718
10.
A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation.
Sci Rep
; 5: 13428, 2015 Aug 27.
Artigo
Inglês
| MEDLINE | ID: mdl-26310318
11.
NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury.
J Mol Med (Berl)
; 90(12): 1391-406, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23090009
12.
[A premature with nail defects]. / Een prematuur met nagelafwijkingen.
Ned Tijdschr Geneeskd
; 154: A205, 2010.
Artigo
Holandês
| MEDLINE | ID: mdl-20170579