Detalhe da pesquisa
1.
A longer isoform of Stim1 is a negative SOCE regulator but increases cAMP-modulated NFAT signaling.
EMBO Rep
; 23(3): e53135, 2022 02 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34942054
2.
Localization of the gate and selectivity filter of the full-length P2X7 receptor.
Proc Natl Acad Sci U S A
; 114(11): E2156-E2165, 2017 03 14.
Artigo
Inglês
| MEDLINE | ID: mdl-28235784
3.
Investigating targets for neuropharmacological intervention by molecular dynamics simulations.
Biochem Soc Trans
; 47(3): 909-918, 2019 06 28.
Artigo
Inglês
| MEDLINE | ID: mdl-31085614
4.
Structural Prediction of the Dimeric Form of the Mammalian Translocator Membrane Protein TSPO: A Key Target for Brain Diagnostics.
Int J Mol Sci
; 19(9)2018 Aug 31.
Artigo
Inglês
| MEDLINE | ID: mdl-30200318
5.
Quantitative Assessment of Drug Delivery to Tissues and Association with Phospholipidosis: A Case Study with Two Structurally Related Diamines in Development.
Mol Pharm
; 14(12): 4362-4373, 2017 12 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29099189
6.
Salt bridge switching from Arg290/Glu167 to Arg290/ATP promotes the closed-to-open transition of the P2X2 receptor.
Mol Pharmacol
; 83(1): 73-84, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23041661
7.
Genome-wide association study of pain sensitivity assessed by questionnaire and the cold pressor test.
Pain
; 163(9): 1763-1776, 2022 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34924555
8.
Molecular determinants of potent P2X2 antagonism identified by functional analysis, mutagenesis, and homology docking.
Mol Pharmacol
; 79(4): 649-61, 2011 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-21191044
9.
Validity of the cold pressor test and pain sensitivity questionnaire via online self-administration.
PLoS One
; 15(4): e0231697, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32298348
10.
Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors.
Neuropharmacology
; 158: 107749, 2019 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31461640
11.
Structural heterogeneity of the µ-opioid receptor's conformational ensemble in the apo state.
Sci Rep
; 8: 45761, 2017 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28368046
12.
Thiol dependent intramolecular locking of Orai1 channels.
Sci Rep
; 6: 33347, 2016 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-27624281
13.
Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.
Curr Med Chem
; 22(7): 799-818, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25439586
14.
Structural Determinants for the Binding of Morphinan Agonists to the µ-Opioid Receptor.
PLoS One
; 10(8): e0135998, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26280453
15.
Discovery of Spiro[cyclohexane-dihydropyrano[3,4-b]indole]-amines as Potent NOP and Opioid Receptor Agonists.
ACS Med Chem Lett
; 5(8): 851-6, 2014 Aug 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25147602
16.
Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol.
ACS Med Chem Lett
; 5(8): 857-62, 2014 Aug 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25147603
17.
Heteromeric assembly of P2X subunits.
Front Cell Neurosci
; 7: 250, 2013 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24391538
18.
Advances in targeting voltage-gated sodium channels with small molecules.
ChemMedChem
; 7(10): 1712-40, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22945552