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Ann Thorac Surg ; 19(3): 309-12, 1975 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-1119885

RESUMO

A simple mathematical model of the hemodynamic effects of a discrete proximal coronary artery obstruction is presented. The model demonstrates that resting myocardial flow demands fail to be met when the vessel diameter is decreased by 75% or greater. More strikingly, it shows that the maximum flow obtainable for increased myocardial oxygen demand begins to fall significantly with a lesion causing a 40 to 50% obstruction. The implications of these findings in relation to stress-induced angina are discussed.


Assuntos
Circulação Coronária , Doença das Coronárias/fisiopatologia , Modelos Biológicos , Resistência Vascular , Humanos
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