Detalhe da pesquisa
1.
Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods.
Pharmacol Rev
; 76(2): 251-266, 2024 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38351072
2.
New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop.
Regul Toxicol Pharmacol
; 114: 104668, 2020 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-32335207
3.
Identification and Profiling of Environmental Chemicals That Inhibit the TGFß/SMAD Signaling Pathway.
Chem Res Toxicol
; 32(12): 2433-2444, 2019 12 16.
Artigo
Inglês
| MEDLINE | ID: mdl-31652400
4.
Computational Model of Secondary Palate Fusion and Disruption.
Chem Res Toxicol
; 30(4): 965-979, 2017 04 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28045533
5.
Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects.
Crit Rev Toxicol
; 47(5): 402-414, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-27766926
6.
ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology.
Chem Res Toxicol
; 29(8): 1225-51, 2016 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27367298
7.
Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects.
Crit Rev Toxicol
; 46(10): 900-910, 2016 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27848393
8.
Systems Toxicology: The Future of Risk Assessment.
Int J Toxicol
; 34(4): 346-8, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25804424
9.
Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses.
Environ Sci Technol
; 48(15): 8706-16, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24960280
10.
Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays.
Chem Res Toxicol
; 26(6): 878-95, 2013 Jun 17.
Artigo
Inglês
| MEDLINE | ID: mdl-23611293
11.
Real-time growth kinetics measuring hormone mimicry for ToxCast chemicals in T-47D human ductal carcinoma cells.
Chem Res Toxicol
; 26(7): 1097-107, 2013 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23682706
12.
High-throughput models for exposure-based chemical prioritization in the ExpoCast project.
Environ Sci Technol
; 47(15): 8479-88, 2013 Aug 06.
Artigo
Inglês
| MEDLINE | ID: mdl-23758710
13.
Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity.
ALTEX
; 40(2): 217236, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-35796328
14.
Society for birth defects research and prevention's multidisciplinary research needs workshop 2022: A call to action.
Birth Defects Res
; 115(10): 959-966, 2023 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37218073
15.
Computational model for fetal skeletal defects potentially linked to disruption of retinoic acid signaling.
Front Pharmacol
; 13: 971296, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36172177
16.
Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues.
Birth Defects Res
; 114(16): 1037-1055, 2022 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35532929
17.
Pluripotent stem cell assays: Modalities and applications for predictive developmental toxicity.
Curr Res Toxicol
; 3: 100074, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35633891
18.
Disruption of embryonic vascular development in predictive toxicology.
Birth Defects Res C Embryo Today
; 93(4): 312-23, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22271680
19.
Zebrafish: as an integrative model for twenty-first century toxicity testing.
Birth Defects Res C Embryo Today
; 93(3): 256-67, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21932434
20.
Predictive model of rat reproductive toxicity from ToxCast high throughput screening.
Biol Reprod
; 85(2): 327-39, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21565999