Detalhe da pesquisa
1.
IL-11 is a crucial determinant of cardiovascular fibrosis.
Nature
; 552(7683): 110-115, 2017 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29160304
2.
Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo.
Hum Mol Genet
; 28(12): 1971-1981, 2019 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30715350
3.
Fibroblast-specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease.
FASEB J
; 34(9): 11802-11815, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32656894
4.
Therapeutic Targeting of Interleukin-11 Signalling Reduces Pressure Overload-Induced Cardiac Fibrosis in Mice.
J Cardiovasc Transl Res
; 14(2): 222-228, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32592090
5.
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH.
Nat Commun
; 12(1): 66, 2021 01 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33397952
6.
Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models.
Sci Rep
; 10(1): 17853, 2020 10 20.
Artigo
Inglês
| MEDLINE | ID: mdl-33082445
7.
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis.
Sci Transl Med
; 11(511)2019 09 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31554736
8.
Titin-truncating variants affect heart function in disease cohorts and the general population.
Nat Genet
; 49(1): 46-53, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27869827