Pesquisa | Secretaria de Estado da Saúde

1.

BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G_q activation at early endosomes.

Wright, Shane C; Lukasheva, Viktoriya; Le Gouill, Christian; Kobayashi, Hiroyuki; Breton, Billy; Mailhot-Larouche, Samuel; Blondel-Tepaz, Élodie; Antunes Vieira, Nichelle; Costa-Neto, Claudio; Héroux, Madeleine; Lambert, Nevin A; Parreiras-E-Silva, Lucas Tabajara; Bouvier, Michel.

Proc Natl Acad Sci U S A ; 118(20)2021 05 18.

Artigo Inglês | MEDLINE | ID: mdl-33990469

2.

Distribution of internal medicine rotations among resident physicians in Japan: a nationwide, multicenter, cross-sectional study.

Shikino, Kiyoshi; Sekine, Miwa; Nishizaki, Yuji; Yamamoto, Yu; Shimizu, Taro; Fukui, Sho; Nagasaki, Kazuya; Yokokawa, Daiki; Watari, Takashi; Kobayashi, Hiroyuki; Tokuda, Yasuharu.

BMC Med Educ ; 24(1): 316, 2024 Mar 20.

Artigo Inglês | MEDLINE | ID: mdl-38509553

3.

The Impact of 5-Aminolevulinic Acid Supplementation on Redox Balance and Aerobic Capacity.

Saga, Norio; Hu, Ailing; Yamaguchi, Takuji; Naraoka, Yuna; Kobayashi, Hiroyuki.

Int J Mol Sci ; 25(2)2024 Jan 12.

Artigo Inglês | MEDLINE | ID: mdl-38256062

4.

Development of conformational BRET biosensors that monitor ezrin, radixin and moesin activation in real time.

Leguay, Kévin; Decelle, Barbara; He, Yu Yan; Pagniez, Anthony; Hogue, Mireille; Kobayashi, Hiroyuki; Le Gouill, Christian; Bouvier, Michel; Carréno, Sébastien.

J Cell Sci ; 134(7)2021 04 01.

Artigo Inglês | MEDLINE | ID: mdl-33712451

5.

Kinetics of serum O-glycosylated M-hepatitis B surface antigen with hepatocellular carcinoma history and nucleos(t)ide analogue therapy in hepatitis B patients.

Okumura, Taiki; Joshita, Satoru; Iwadare, Takanobu; Wakabayashi, Shun-Ichi; Kobayashi, Hiroyuki; Yamashita, Yuki; Sugiura, Ayumi; Kimura, Takefumi; Umemura, Takeji.

J Viral Hepat ; 30(9): 731-739, 2023 09.

Artigo Inglês | MEDLINE | ID: mdl-37363934

6.

Association between regional quota program in medical schools and practical clinical competency based on General Medicine In-Training Examination score: a nationwide cross-sectional study of resident physicians in Japan.

Fukui, Sho; Shikino, Kiyoshi; Nishizaki, Yuji; Shimizu, Taro; Yamamoto, Yu; Kobayashi, Hiroyuki; Tokuda, Yasuharu.

Postgrad Med J ; 99(1177): 1197-1204, 2023 Oct 19.

Artigo Inglês | MEDLINE | ID: mdl-37474744

7.

Association between prolonged weekly duty hours and self-study time among residents: a cross-sectional study.

Nagasaki, Kazuya; Nishizaki, Yuji; Shinozaki, Tomohiro; Shimizu, Taro; Yamamoto, Yu; Shikino, Kiyoshi; Fukui, Sho; Nishiguchi, Sho; Kurihara, Masaru; Katayama, Kohta; Kobayashi, Hiroyuki; Tokuda, Yasuharu.

Postgrad Med J ; 99(1176): 1080-1087, 2023 Sep 21.

Artigo Inglês | MEDLINE | ID: mdl-37265446

8.

Smartphone App-Based and Paper-Based Patient-Reported Outcomes Using a Disease-Specific Questionnaire for Dry Eye Disease: Randomized Crossover Equivalence Study.

Nagino, Ken; Okumura, Yuichi; Akasaki, Yasutsugu; Fujio, Kenta; Huang, Tianxiang; Sung, Jaemyoung; Midorikawa-Inomata, Akie; Fujimoto, Keiichi; Eguchi, Atsuko; Hurramhon, Shokirova; Yee, Alan; Miura, Maria; Ohno, Mizu; Hirosawa, Kunihiko; Morooka, Yuki; Murakami, Akira; Kobayashi, Hiroyuki; Inomata, Takenori.

J Med Internet Res ; 25: e42638, 2023 08 03.

Artigo Inglês | MEDLINE | ID: mdl-37535409

9.

2-Step PLT16-AST44 method: Simplified liver fibrosis detection system in patients with non-alcoholic fatty liver disease.

Fujimori, Naoyuki; Kimura, Takefumi; Tanaka, Naoki; Yamazaki, Tomoo; Okumura, Taiki; Kobayashi, Hiroyuki; Wakabayashi, Shun-Ichi; Yamashita, Yuki; Sugiura, Ayumi; Pham, Jonathan; Pydi, Sai P; Sano, Kenji; Joshita, Satoru; Umemura, Takeji.

Hepatol Res ; 52(4): 352-363, 2022 Apr.

Artigo Inglês | MEDLINE | ID: mdl-35040549

10.

A pilot study examining the efficacy of hochuekkito for improving quality of life in patients with myeloproliferative neoplasms.

Edahiro, Yoko; Koike, Michiaki; Nojiri, Shuko; Harada, Yoshinao; Gotoh, Akihiko; Fujibayashi, Kazutoshi; Nishizaki, Yuji; Yanagisawa, Naotake; Takaku, Tomoiku; Nitta, Hideaki; Tsukune, Yutaka; Misawa, Kyohei; Kobayashi, Hiroyuki; Komatsu, Norio.

Jpn J Clin Oncol ; 52(8): 880-886, 2022 08 05.

Artigo Inglês | MEDLINE | ID: mdl-35575284

11.

Cystic Intracranial Recurrence of Olfactory Neuroblastoma without Accumulation on Fluorine-18-fluorodeoxyglucose Positron Emission Tomography.

Ishi, Yukitomo; Yamaguchi, Shigeru; Hatanaka, Kanako C; Takakuwa, Emi; Motegi, Hiroaki; Honda, Taishi; Kobayashi, Hiroyuki; Terasaka, Shunsuke; Homma, Akihiro; Fujimura, Miki; Houkin, Kiyohiro.

Acta Med Okayama ; 76(1): 93-98, 2022 Feb.

Artigo Inglês | MEDLINE | ID: mdl-35237005

12.

Impact of the resident duty hours on in-training examination score: A nationwide study in Japan.

Nagasaki, Kazuya; Nishizaki, Yuji; Shinozaki, Tomohiro; Kobayashi, Hiroyuki; Shimizu, Taro; Okubo, Tomoya; Yamamoto, Yu; Konishi, Ryota; Tokuda, Yasuharu.

Med Teach ; 44(4): 433-440, 2022 04.

Artigo Inglês | MEDLINE | ID: mdl-34818129

13.

Intermolecular Halogen Bond Detected in Racemic and Optically Pure N-C Axially Chiral 3-(2-Halophenyl)quinazoline-4-thione Derivatives.

Matsui, Ryosuke; Niijima, Erina; Imai, Tomomi; Kobayashi, Hiroyuki; Hori, Akiko; Sato, Azusa; Nakamura, Yuko; Kitagawa, Osamu.

Molecules ; 27(7)2022 Apr 06.

Artigo Inglês | MEDLINE | ID: mdl-35408762

14.

Comprehensive Glycomic Approach Reveals Novel Low-Molecular-Weight Blood Group-Specific Glycans in Serum and Cerebrospinal Fluid.

Furukawa, Jun-Ichi; Hanamatsu, Hisatoshi; Yokota, Ikuko; Hirayama, Megumi; Ando, Tomohiro; Kobayashi, Hiroyuki; Ohnishi, Shunsuke; Miura, Nobuaki; Okada, Kazue; Sakai, Shota; Yuyama, Kohei; Igarashi, Yasuyuki; Ito, Makoto; Shinohara, Yasuro; Sakamoto, Naoya.

J Proteome Res ; 20(5): 2812-2822, 2021 05 07.

Artigo Inglês | MEDLINE | ID: mdl-33719461

15.

Determination of brain tumor recurrence using ¹¹ C-methionine positron emission tomography after radiotherapy.

Yamaguchi, Shigeru; Hirata, Kenji; Okamoto, Michinari; Shimosegawa, Eku; Hatazawa, Jun; Hirayama, Ryuichi; Kagawa, Naoki; Kishima, Haruhiko; Oriuchi, Noboru; Fujii, Masazumi; Kobayashi, Kentaro; Kobayashi, Hiroyuki; Terasaka, Shunsuke; Nishijima, Ken-Ichi; Kuge, Yuji; Ito, Yoichi M; Nishihara, Hiroshi; Tamaki, Nagara; Shiga, Tohru.

Cancer Sci ; 112(10): 4246-4256, 2021 Oct.

Artigo Inglês | MEDLINE | ID: mdl-34061417

16.

Safety and efficacy of depatuxizumab mafodotin in Japanese patients with malignant glioma: A nonrandomized, phase 1/2 trial.

Narita, Yoshitaka; Muragaki, Yoshihiro; Kagawa, Naoki; Asai, Katsunori; Nagane, Motoo; Matsuda, Masahide; Ueki, Keisuke; Kuroda, Junichiro; Date, Isao; Kobayashi, Hiroyuki; Kumabe, Toshihiro; Beppu, Takaaki; Kanamori, Masayuki; Kasai, Shota; Nishimura, Yasuko; Xiong, Hao; Ocampo, Christopher; Yamada, Masakazu; Mishima, Kazuhiko.

Cancer Sci ; 112(12): 5020-5033, 2021 Dec.

Artigo Inglês | MEDLINE | ID: mdl-34609773

17.

aMAP score prediction of hepatocellular carcinoma occurrence and incidence-free rate after a sustained virologic response in chronic hepatitis C.

Yamashita, Yuki; Joshita, Satoru; Sugiura, Ayumi; Yamazaki, Tomoo; Kobayashi, Hiroyuki; Wakabayashi, Shun-Ichi; Yamada, Yosuke; Shibata, Soichiro; Kunimoto, Hideo; Iwadare, Takanobu; Matsumura, Makiko; Miyabayashi, Chiharu; Okumura, Taiki; Ozawa, Sachie; Nozawa, Yuichi; Kobayashi, Natsuko; Komatsu, Michiharu; Fujimori, Naoyuki; Saito, Hiromi; Umemura, Takeji.

Hepatol Res ; 51(9): 933-942, 2021 Sep.

Artigo Inglês | MEDLINE | ID: mdl-34216422

18.

Beta-arrestins operate an on/off control switch for focal adhesion kinase activity.

Alexander, Revu Ann; Lot, Isaure; Saha, Kusumika; Abadie, Guillaume; Lambert, Mireille; Decosta, Eleonore; Kobayashi, Hiroyuki; Beautrait, Alexandre; Borrull, Aurélie; Asnacios, Atef; Bouvier, Michel; Scott, Mark G H; Marullo, Stefano; Enslen, Hervé.

Cell Mol Life Sci ; 77(24): 5259-5279, 2020 Dec.

Artigo Inglês | MEDLINE | ID: mdl-32040695

19.

Successful treatment by glecaprevir/pibrentasvir followed by hepatoprotective therapy of acute chronic hepatitis exacerbation caused by daratumumab-based regimen for multiple myeloma: Case report and review of the literature.

Yamazaki, Tomoo; Joshita, Satoru; Ichijo, Tetsuya; Kobayashi, Hiroyuki; Wakabayashi, Shun-Ichi; Yamashita, Yuki; Sugiura, Ayumi; Kawakami, Fumihiro; Nakazawa, Hideyuki; Umemura, Takeji.

J Infect Chemother ; 27(12): 1750-1755, 2021 Dec.

Artigo Inglês | MEDLINE | ID: mdl-34344581

20.

Serum albumin levels as a predictive biomarker for low-load resistance training programs' effects on muscle thickness in the community-dwelling elderly Japanese population: interventional study result.

Sawada, Shuji; Ozaki, Hayao; Natsume, Toshiharu; Nakano, Daiki; Deng, Pengyu; Yoshihara, Toshinori; Osawa, Takuya; Kobayashi, Hiroyuki; Machida, Shuichi; Naito, Hisashi.

BMC Geriatr ; 21(1): 464, 2021 08 18.

Artigo Inglês | MEDLINE | ID: mdl-34407763

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