Detalhe da pesquisa
1.
Palbociclib with adjuvant endocrine therapy in early breast cancer (PALLAS): interim analysis of a multicentre, open-label, randomised, phase 3 study.
Lancet Oncol
; 22(2): 212-222, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33460574
2.
Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer.
N Engl J Med
; 373(3): 209-19, 2015 Jul 16.
Artigo
Inglês
| MEDLINE | ID: mdl-26030518
3.
Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial.
Lancet Oncol
; 17(4): 425-439, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26947331
4.
Breakthrough cancer medicine and its impact on novel drug development in China: report of the US Chinese Anti-Cancer Association (USCACA) and Chinese Society of Clinical Oncology (CSCO) Joint Session at the 17th CSCO Annual Meeting.
Chin J Cancer
; 33(12): 620-4, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25418191
5.
Development of a Practical Nomogram for Personalized Anemia Management in Patients Treated with Ataxia Telangiectasia and Rad3-related Inhibitor Camonsertib.
Clin Cancer Res
; 30(4): 687-694, 2024 02 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38078898
6.
ATR inhibitor, camonsertib, dose optimization in patients with biomarker-selected advanced solid tumors (TRESR study).
J Natl Cancer Inst
; 2024 May 06.
Artigo
Inglês
| MEDLINE | ID: mdl-38710487
7.
Detection of Biallelic Loss of DNA Repair Genes in Formalin-Fixed, Paraffin-Embedded Tumor Samples Using a Novel Tumor-Only Sequencing Panel.
J Mol Diagn
; 25(5): 295-310, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36944408
8.
Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results.
Nat Med
; 29(6): 1400-1411, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37277454
9.
Genomic Profiling Reveals Germline Predisposition and Homologous Recombination Deficiency in Pancreatic Acinar Cell Carcinoma.
J Clin Oncol
; 41(33): 5151-5162, 2023 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37607324
10.
ATM Germline-Mutated Gastroesophageal Junction Adenocarcinomas: Clinical Descriptors, Molecular Characteristics, and Potential Therapeutic Implications.
J Natl Cancer Inst
; 114(5): 761-770, 2022 05 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35078243
11.
Synthetic Lethality in Cancer Therapeutics: The Next Generation.
Cancer Discov
; 11(7): 1626-1635, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33795234
12.
Palbociclib for Residual High-Risk Invasive HR-Positive and HER2-Negative Early Breast Cancer-The Penelope-B Trial.
J Clin Oncol
; 39(14): 1518-1530, 2021 05 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33793299
13.
HER-2 gene amplification, HER-2 and epidermal growth factor receptor mRNA and protein expression, and lapatinib efficacy in women with metastatic breast cancer.
Clin Cancer Res
; 14(23): 7861-70, 2008 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19047115
14.
Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor-Positive Early Breast Cancer: PALLET Trial.
J Clin Oncol
; 37(3): 178-189, 2019 01 20.
Artigo
Inglês
| MEDLINE | ID: mdl-30523750
15.
Pooled analysis of diarrhea events in patients with cancer treated with lapatinib.
Breast Cancer Res Treat
; 112(2): 317-25, 2008 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-18204897
16.
Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer.
Nat Commun
; 9(1): 896, 2018 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29497091
17.
NeoPalAna: Neoadjuvant Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, and Anastrozole for Clinical Stage 2 or 3 Estrogen Receptor-Positive Breast Cancer.
Clin Cancer Res
; 23(15): 4055-4065, 2017 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28270497
18.
Phase II and tumor pharmacodynamic study of gefitinib in patients with advanced breast cancer.
J Clin Oncol
; 23(23): 5323-33, 2005 Aug 10.
Artigo
Inglês
| MEDLINE | ID: mdl-15939921
19.
Plasma ESR1 Mutations and the Treatment of Estrogen Receptor-Positive Advanced Breast Cancer.
J Clin Oncol
; 34(25): 2961-8, 2016 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27269946
20.
Deciding priorities in Pharma.
Breast Cancer Res
; 12 Suppl 4: S21, 2010 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-21172084