RESUMO
The nonuniform distribution of thrombocytes in a microvessel is considered in terms of a previously advanced phenomenological theory, which describes the relationship between the mean blood velocity and thrombus growth rate.
Assuntos
Microcirculação , Trombose/patologia , Modelos Biológicos , Ativação PlaquetáriaRESUMO
The growth rate constant of platelet thrombi as a function of mean blood flow velocity was studied using mesentery vessels of the white rat. An advanced mathematical model for the kinetics of platelet thrombi was developed. The dependence of platelet activation delay time upon the distance from the damaged vessel wall is pointed out as a result of theoretical and experimental data comparison.
Assuntos
Velocidade do Fluxo Sanguíneo , Microcirculação/fisiopatologia , Adesividade Plaquetária , Agregação Plaquetária , Trombose/fisiopatologia , Humanos , Modelos TeóricosRESUMO
A comparative analysis of rat mesentery micro vascular reactions on thermal impact during radiation to the focused laser irradiation in UV and visible regions of spectrum is made. Local intravascular temperature rise during laser irradiation both impulse (lambda = 337 nm) and continuous (lambda = 532 nm) states causes thrombus formation. The thrombus development that determined by laser irradiation parameters gives a possibility to modulate different degrees of microvessel endothelium damage.