Carotid-Cavernous Fistula as a Complication of Facial Trauma: A Case Report.

Posttraumatic carotid-cavernous fistula is a very rare complication that can occur in patients with craniomaxillofacial trauma. Symptoms involve headache, diplopia, ptosis of the upper lid, conjunctival chemosis, pulsating exophthalmos, and ophthalmoplegia. Diagnosis can be challenging because various pathologic entities can present with similar symptoms such as superior orbital fissure syndrome, orbital apex syndrome, retrobulbar hematoma, and cavernous sinus syndrome. However, accurate and early diagnosis is of utmost importance because treatment delay may lead to blindness or permanent neurologic deficits. In this article, a case of posttraumatic carotid-cavernous fistula that was twice misdiagnosed is presented.

Metastatic Tumours to the Oral Cavity: Report of Three Cases.

BACKGROUND: Metastatic tumours to the oral cavity from distant organs are uncommon and represent approximately 1 - 3% of all oral malignancies. Such metastases can occur to the bone or to the oral soft tissues. Almost any malignancy from any site is capable of metastasis to the oral cavity and a wide variety of tumours have been reported to spread to the mouth. METHODS: Careful examination of the oral cavity and a high degree of clinical suspicion as well as a multidisciplinary approach are suggested. RESULTS: In this article we present three patients, a female and two males with metastatic tumours to the oral cavity, who were referred to our Department. The primary tumours were invasive lobular breast carcinoma, gastric adenocarcinoma and small cell lung carcinoma respectively. CONCLUSIONS: Metastases to the oral cavity are quite uncommon among population. They usually present with symptoms similar to odontogenic infections and benign tumours, causing a delayed diagnosis and treatment.

Inflammatory myofibroblastic tumour of the maxillary sinus and the oral cavity.

BACKGROUND: Inflammatory myofibroblastic tumours (IMT) are benign lesions that mimic malignant neoplastic processes due to their infiltrating and destructive nature. They can be found anywhere in the body, although they are most commonly located in the lung. IMTs of the head and neck region are rare entities. CASE REPORT: We report a case of a maxillary IMT with an enlarged intraoral component which was adequately treated with surgical excision without long-lasting additional corticosteroid treatment. DISCUSSION: Inflammatory myofibroblastic tumours can be easily misdiagnosed as malignant neoplastic processes due to their destructive nature. Proper diagnosis is essential to avoid mutilating and disfiguring surgical procedures.

Quality of life in breast cancer patients with bisphosphonate-related osteonecrosis of the jaws and patients with head and neck cancer: a comparative study using the EORTC QLQ-C30 and QLQ-HN35 questionnaires.

BACKGROUND/AIM: This exploratory study aimed at examining the diagnostic utility, validity and reliability of already established quality of life (QoL) measures in cancer patients with osteonecrosis of the jaws (ONJ). PATIENTS AND METHODS: This was a prospective, observational, controlled clinical study. Female patients diagnosed with metastatic breast cancer and stage 2 or 3 ONJ (group I), metastatic breast cancer alone (group II), or cancer of the oral cavity (group III) were questioned. The EORTC QLQ-C30 version 3.0 and the QLQ-HN35 head and neck-specific questionnaires were used. RESULTS: Completed questionnaires were obtained from 64 patients. Overall internal consistency was acceptable to excellent with a Cronbach's alpha of 0.728 to 0.892. The Spearman-Brown coefficient was 0.888 and 0.872 for QLQ-C30 and HN35, respectively. Several scales of the questionnaire were sensitive to patient group: Global health status/Qol, HN Social eating, HN Pain, HN Swallowing, HN Senses, Role Function. Symptom intensity correlated with ONJ stage (2 vs. 3). CONCLUSION: EORTC QLQ-HN35 in conjunction with QLQ-C30 is a valid and informative tool in assessing QoL in patients with metastatic breast cancer and ONJ. Administration of the instrument to patients with ONJ of various nationalities is feasible and such efforts would greatly assist in recording the additional health burden created by this complication of bisphosphonate therapy. The use of HN35 module may be feasible in patients with any type of metastatic cancer who develop ONJ.