Detalhe da pesquisa
1.
Microsomal prostaglandin E synthase-1 inhibition promotes shunting in arachidonic acid metabolism during inflammatory responses in vitro.
Prostaglandins Other Lipid Mediat
; 167: 106738, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37094780
2.
Biosynthesis of prostaglandin 15dPGJ2 -glutathione and 15dPGJ2-cysteine conjugates in macrophages and mast cells via MGST3.
J Lipid Res
; 63(12): 100310, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36370807
3.
Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis.
J Intern Med
; 292(5): 745-763, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35854675
4.
Establishment of an in vitro 3D model for neuroblastoma enables preclinical investigation of combined tumor-stroma drug targeting.
FASEB J
; 34(8): 11101-11114, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32623799
5.
miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction.
FASEB J
; 33(6): 6933-6947, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30922080
6.
COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset.
Proc Natl Acad Sci U S A
; 112(26): 8070-5, 2015 Jun 30.
Artigo
Inglês
| MEDLINE | ID: mdl-26080408
7.
Immunomodulatory effects of nicotine on interleukin 1ß activated human astrocytes and the role of cyclooxygenase 2 in the underlying mechanism.
J Neuroinflammation
; 13(1): 256, 2016 Sep 29.
Artigo
Inglês
| MEDLINE | ID: mdl-27681882
8.
Deletion of mPGES-1 affects platelet functions in mice.
Clin Sci (Lond)
; 130(24): 2295-2303, 2016 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27758933
9.
Impaired vagus-mediated immunosuppression in microsomal prostaglandin E synthase-1 deficient mice.
Prostaglandins Other Lipid Mediat
; 121(Pt B): 155-62, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-26001880
10.
NG2 glia protect against prion neurotoxicity by inhibiting microglia-to-neuron prostaglandin E2 signaling.
Nat Neurosci
; 2024 May 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38802591
11.
High-content screening of drug combinations of an mPGES-1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance.
Mol Oncol
; 18(2): 317-335, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-37519014
12.
High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2.
Front Immunol
; 15: 1372927, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38742105
13.
Urinary prostanoids are elevated by anti-TNF and anti-IL6 receptor disease-modifying antirheumatic drugs but are not predictive of response to treatment in early rheumatoid arthritis.
Arthritis Res Ther
; 26(1): 61, 2024 Mar 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38444034
14.
Lack of microsomal prostaglandin E(2) synthase-1 in bone marrow-derived myeloid cells impairs left ventricular function and increases mortality after acute myocardial infarction.
Circulation
; 125(23): 2904-13, 2012 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-22589381
15.
Activated LTB4 pathway in muscle tissue of patients with polymyositis or dermatomyositis.
Ann Rheum Dis
; 72(2): 293-9, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22736094
16.
Effects of mPGES-1 deletion on eicosanoid and fatty acid profiles in mice.
Prostaglandins Other Lipid Mediat
; 107: 18-25, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23916744
17.
Characterization of a new mPGES-1 inhibitor in rat models of inflammation.
Prostaglandins Other Lipid Mediat
; 102-103: 1-12, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23528231
18.
Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation.
Prostaglandins Other Lipid Mediat
; 107: 26-34, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24045148
19.
Microsomal prostaglandin E synthase-1 inhibition prevents adverse cardiac remodelling after myocardial infarction in mice.
Br J Pharmacol
; 180(15): 1981-1998, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36788645
20.
Expression of prostaglandin E synthases in periodontitis immunolocalization and cellular regulation.
Am J Pathol
; 178(4): 1676-88, 2011 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-21435451