Detalhe da pesquisa
1.
Novel 3,9-Disubstituted Acridines with Strong Inhibition Activity against Topoisomerase I: Synthesis, Biological Evaluation and Molecular Docking Study.
Molecules
; 28(3)2023 Jan 30.
Artigo
Inglês
| MEDLINE | ID: mdl-36770975
2.
Acridine derivatives as inhibitors/poisons of topoisomerase II.
J Appl Toxicol
; 42(4): 544-552, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34514603
3.
Acridine Based N-Acylhydrazone Derivatives as Potential Anticancer Agents: Synthesis, Characterization and ctDNA/HSA Spectroscopic Binding Properties.
Molecules
; 27(9)2022 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-35566236
4.
A new look at 9-substituted acridines with various biological activities.
J Appl Toxicol
; 41(1): 175-189, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32969520
5.
Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells.
Int J Mol Sci
; 22(8)2021 Apr 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33917200
6.
Synthesis of Novel Biologically Active Proflavine Ureas Designed on the Basis of Predicted Entropy Changes.
Molecules
; 26(16)2021 Aug 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34443446
7.
Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines.
Molecules
; 26(4)2021 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-33672694
8.
Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity.
Bioorg Chem
; 94: 103393, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31679839
9.
Proflavine/acriflavine derivatives with versatile biological activities.
J Appl Toxicol
; 40(1): 64-71, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31222780
10.
Proliferation inhibition of novel diphenylamine derivatives.
Bioorg Chem
; 83: 487-499, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30453141
11.
In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers.
J Enzyme Inhib Med Chem
; 34(1): 877-897, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-30938202
12.
Multifunctional properties of novel tacrine congeners: cholinesterase inhibition and cytotoxic activity.
J Appl Toxicol
; 38(11): 1377-1387, 2018 11.
Artigo
Inglês
| MEDLINE | ID: mdl-29624715
13.
A review on acridinylthioureas and its derivatives: biological and cytotoxic activity.
J Appl Toxicol
; 37(10): 1132-1139, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28370171
14.
Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.
Bioorg Chem
; 59: 168-76, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25827869
15.
Novel trisubstituted acridines as human telomeric quadruplex binding ligands.
Bioorg Chem
; 57: 13-29, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25171773
16.
Interaction of 3,9-disubstituted acridine with single stranded poly(rA), double stranded poly(rAU) and triple stranded poly(rUAU): molecular docking - A spectroscopic tandem study.
Chem Biol Interact
; 394: 110965, 2024 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38552767
17.
Chili pepper extracts, capsaicin, and dihydrocapsaicin as potential anticancer agents targeting topoisomerases.
BMC Complement Med Ther
; 24(1): 96, 2024 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38383414
18.
DNA binding acridine-thiazolidinone agents affecting intracellular glutathione.
Bioorg Med Chem
; 20(24): 7139-48, 2012 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23122936
19.
Cytotoxic 3,6-bis((imidazolidinone)imino)acridines: synthesis, DNA binding and molecular modeling.
Bioorg Med Chem
; 19(5): 1790-801, 2011 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21315610
20.
Spectroscopic, structural and theoretical studies of novel, potentially cytotoxic 4-acridonecarboxamide imines.
Spectrochim Acta A Mol Biomol Spectrosc
; 73(2): 238-48, 2009 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19303354