Detalhe da pesquisa
1.
EDC3 phosphorylation regulates growth and invasion through controlling P-body formation and dynamics.
EMBO Rep
; 22(4): e50835, 2021 04 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33586867
2.
OER-073: A multicenter phase 2 study evaluating the role of pazopanib in angiosarcoma.
Cancer
; 128(19): 3516-3522, 2022 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35942596
3.
Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth.
Proc Natl Acad Sci U S A
; 116(41): 20505-20510, 2019 10 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31548394
4.
Synthesis of 2-Oxoquinoline Derivatives as Dual Pim and mTORC Protein Kinase Inhibitors.
Med Chem Res
; 31(7): 1154-1175, 2022 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-36389181
5.
A randomized, open-label, phase 2, multicenter trial of gemcitabine with pazopanib or gemcitabine with docetaxel in patients with advanced soft-tissue sarcoma.
Cancer
; 127(6): 894-904, 2021 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33231866
6.
SMACing down relapsed T-ALL.
Blood
; 143(21): 2116-2117, 2024 May 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38780917
7.
"Root"ing for successful T-ALL treatment.
Blood
; 137(18): 2422-2423, 2021 05 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33956068
8.
Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases.
Circ Res
; 115(3): 376-87, 2014 Jul 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24916111
9.
Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells.
Stem Cells
; 31(6): 1202-12, 2013 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-23495171
10.
The Pim protein kinases regulate energy metabolism and cell growth.
Proc Natl Acad Sci U S A
; 108(2): 528-33, 2011 Jan 11.
Artigo
Inglês
| MEDLINE | ID: mdl-21187426
11.
Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial.
Lancet Oncol
; 14(4): 371-82, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23477833
12.
Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation.
Eur J Immunol
; 42(4): 1044-50, 2012 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-22531928
13.
A phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy.
Anticancer Drugs
; 24(7): 743-53, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23652277
14.
An XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells.
Sci Immunol
; 8(81): eabn7993, 2023 03 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36897958
15.
PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion.
J Cell Biol
; 222(6)2023 06 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37042842
16.
A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma.
Blood
; 115(4): 824-33, 2010 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-19965690
17.
Regulation of Skp2 levels by the Pim-1 protein kinase.
J Biol Chem
; 285(38): 29128-37, 2010 Sep 17.
Artigo
Inglês
| MEDLINE | ID: mdl-20663873
18.
Sustained response to pembrolizumab in recurrent perivascular epithelioid cell tumor with elevated expression of programmed death ligand: a case report.
J Med Case Rep
; 15(1): 400, 2021 Jul 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34301321
19.
The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.
Nat Commun
; 12(1): 7349, 2021 12 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34934057
20.
PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis.
Mol Cancer Ther
; 19(9): 1809-1821, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32753387