RESUMO
AIM: To assess the effectiveness of the collagen biomaterial in treatment process in patients with DFS. MATERIAL AND METHODS: 71 patients 30-80 y.o. with diabetic foot syndrome of varying severity were included in prospective multicenter study. Patients were randomized into two homogeneous groups: control group (n=35) - standard therapy, other 36 patients (main group) were additionally treated with medical device (MD) Collost in accordance with the instructions for use. RESULTS: Biomaterial Collost using in complex treatment of diabetic foot syndrome resulted in more rapid and effective healing of the ulcer. The treatment success increased from 43% to 72%. Complete epithelialization was achieved by 2.6 times more rapidly in conjunction with reduction the incidence of unsuccessful treatment results by 4.1 times.
Assuntos
Colágeno , Pé Diabético , Reepitelização/efeitos dos fármacos , Idoso , Materiais Biocompatíveis/administração & dosagem , Materiais Biocompatíveis/farmacocinética , Disponibilidade Biológica , Colágeno/administração & dosagem , Colágeno/farmacocinética , Pé Diabético/diagnóstico , Pé Diabético/tratamento farmacológico , Pé Diabético/fisiopatologia , Monitoramento de Medicamentos/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Terapia de Tecidos Moles/métodos , Resultado do TratamentoRESUMO
Study results of the laser irradiation impact on the blood lipid and phospholipid components and membrane erythrocyte in patients with diabetes mellitus and pyo-necrotic injuries of lower extremities when treated by laser intravenously or epicutaneously. The results prove, that the laser irradiation of low intensity favourably affects the blood components in a complex treatment of diabetes mellitus. Intravenous irradiation positive dynamics are more easily observed.