Detalhe da pesquisa
1.
From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection.
Proc Natl Acad Sci U S A
; 115(4): E802-E811, 2018 01 23.
Artigo
Inglês
| MEDLINE | ID: mdl-29279368
2.
Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography.
Proc Natl Acad Sci U S A
; 114(36): 9725-9730, 2017 09 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28827354
3.
Molecular and cellular studies evaluating a potent 2-cyanoindolizine catechol diether NNRTI targeting wildtype and Y181C mutant HIV-1 reverse transcriptase.
Bioorg Med Chem Lett
; 29(16): 2182-2188, 2019 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31281023
4.
DRONE: Direct Tracking of DNA Cytidine Deamination and Other DNA Modifying Activities.
Anal Chem
; 90(20): 11735-11740, 2018 10 16.
Artigo
Inglês
| MEDLINE | ID: mdl-30256094
5.
Structural and Preclinical Studies of Computationally Designed Non-Nucleoside Reverse Transcriptase Inhibitors for Treating HIV infection.
Mol Pharmacol
; 91(4): 383-391, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28167742
6.
Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2.
J Biol Chem
; 290(20): 12793-803, 2015 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25825493
7.
13-Methylarachidonic acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase.
J Biol Chem
; 290(12): 7897-909, 2015 Mar 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25648895
8.
Reply to Pandey et al.: Understanding the efficacy of a potential antiretroviral drug candidate in humanized mouse model of HIV infection.
Proc Natl Acad Sci U S A
; 115(35): E8114-E8115, 2018 08 28.
Artigo
Inglês
| MEDLINE | ID: mdl-30097540
9.
A role for catalase-peroxidase large loop 2 revealed by deletion mutagenesis: control of active site water and ferric enzyme reactivity.
Biochemistry
; 54(8): 1648-62, 2015 Mar 03.
Artigo
Inglês
| MEDLINE | ID: mdl-25674665
10.
Long-acting and extended-release implant and nanoformulations with a synergistic antiretroviral two-drug combination controls HIV-1 infection in a humanized mouse model.
Bioeng Transl Med
; 7(1): e10237, 2022 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-35079625
11.
Erratum: Exploring APOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.
iScience
; 25(10): 105271, 2022 Oct 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36248736
12.
Exploring ABOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.
iScience
; 25(10): 105077, 2022 Oct 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36164654
13.
Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations.
ACS Cent Sci
; 7(3): 467-475, 2021 Mar 24.
Artigo
Inglês
| MEDLINE | ID: mdl-33786375
14.
Structure-Guided Identification of DNMT3B Inhibitors.
ACS Med Chem Lett
; 11(5): 971-976, 2020 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32435413
15.
Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV.
Antiviral Res
; 167: 110-116, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31034849
16.
Assay of Endocannabinoid Oxidation by Cyclooxygenase-2.
Methods Mol Biol
; 1412: 205-15, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27245906
17.
Enhancing the peroxidatic activity of KatG by deletion mutagenesis.
J Inorg Biochem
; 116: 106-15, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23018273