Detalhe da pesquisa
1.
Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor.
Chemistry
; 29(23): e202203967, 2023 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36799129
2.
Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding.
Chembiochem
; 18(23): 2340-2350, 2017 12 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28950050
3.
Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J Biol Chem
; 290(26): 16415-30, 2015 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-25979334
4.
Expression and Purification of EPHA2 Tyrosine Kinase Domain for Crystallographic and NMR Studies.
Chembiochem
; 17(23): 2257-2263, 2016 12 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27685543
5.
MOTOR: model assisted software for NMR structure determination.
Proteins
; 81(11): 2007-22, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23852655
6.
Structural analysis of the C-terminal domain of the spliceosomal helicase Prp22.
Biol Chem
; 393(10): 1131-40, 2012 Sep 08.
Artigo
Inglês
| MEDLINE | ID: mdl-23096351
7.
Recombinant expression and purification of human TATA binding protein using a chimeric fusion.
Protein Expr Purif
; 85(1): 142-7, 2012 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-22841618
8.
Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex.
J Biol Chem
; 285(34): 26628-40, 2010 Aug 20.
Artigo
Inglês
| MEDLINE | ID: mdl-20547770
9.
Cysteine oxidation and disulfide formation in the ribosomal exit tunnel.
Nat Commun
; 11(1): 5569, 2020 11 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33149120
10.
Crystallization and preliminary X-ray diffraction analysis of the C-terminal domain of the human spliceosomal DExD/H-box protein hPrp22.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 65(Pt 9): 956-8, 2009 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19724143
11.
Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma.
Mol Oncol
; 13(11): 2441-2459, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31545551
12.
Molecular tuning of farnesoid X receptor partial agonism.
Nat Commun
; 10(1): 2915, 2019 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31266946
13.
On the Implication of Water on Fragment-to-Ligand Growth in Kinase Binding Thermodynamics.
ChemMedChem
; 13(18): 1988-1996, 2018 09 19.
Artigo
Inglês
| MEDLINE | ID: mdl-30058283
14.
Paradoxically, Most Flexible Ligand Binds Most Entropy-Favored: Intriguing Impact of Ligand Flexibility and Solvation on Drug-Kinase Binding.
J Med Chem
; 61(14): 5922-5933, 2018 Jul 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29909615
15.
Modulation of the Allosteric Communication between the Polo-Box Domain and the Catalytic Domain in Plk1 by Small Compounds.
ACS Chem Biol
; 13(8): 1921-1931, 2018 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29927572
16.
NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
ChemMedChem
; 13(16): 1629-1633, 2018 08 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29928781
17.
Chemoproteomics-Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors.
ChemMedChem
; 12(12): 999-1011, 2017 06 21.
Artigo
Inglês
| MEDLINE | ID: mdl-28544567
18.
Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.
ACS Chem Biol
; 11(12): 3400-3411, 2016 12 16.
Artigo
Inglês
| MEDLINE | ID: mdl-27768280
19.
High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus.
Acta Crystallogr F Struct Biol Commun
; 71(Pt 8): 1088-93, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26249705
20.
Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells.
ACS Chem Biol
; 10(11): 2570-9, 2015 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-26279064