Detalhe da pesquisa
1.
Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site.
Cell
; 137(2): 332-43, 2009 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-19379698
2.
PAR2 promotes impaired glucose uptake and insulin resistance in NAFLD through GLUT2 and Akt interference.
Hepatology
; 76(6): 1778-1793, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35603482
3.
Lipid Receptor GPR31 (G-Protein-Coupled Receptor 31) Regulates Platelet Reactivity and Thrombosis Without Affecting Hemostasis.
Arterioscler Thromb Vasc Biol
; 41(1): e33-e45, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33267659
4.
Deficiency of MMP1a (Matrix Metalloprotease 1a) Collagenase Suppresses Development of Atherosclerosis in Mice: Translational Implications for Human Coronary Artery Disease.
Arterioscler Thromb Vasc Biol
; 41(5): e265-e279, 2021 05 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33761760
5.
PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled, Phase 2 Study.
Arterioscler Thromb Vasc Biol
; 40(12): 2990-3003, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33028101
6.
Trace amine-associated receptor 1 (TAAR1) promotes anti-diabetic signaling in insulin-secreting cells.
J Biol Chem
; 294(12): 4401-4411, 2019 03 22.
Artigo
Inglês
| MEDLINE | ID: mdl-30670596
7.
'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage.
Nat Immunol
; 8(12): 1303-12, 2007 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-17965715
9.
Atorvastatin Decreases Renal Menaquinone-4 Formation in C57BL/6 Male Mice.
J Nutr
; 149(3): 416-421, 2019 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30753659
10.
Noncanonical Matrix Metalloprotease 1-Protease-Activated Receptor 1 Signaling Drives Progression of Atherosclerosis.
Arterioscler Thromb Vasc Biol
; 38(6): 1368-1380, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29622563
11.
Protease-Activated Receptor 1 as Therapeutic Target in Breast, Lung, and Ovarian Cancer: Pepducin Approach.
Int J Mol Sci
; 19(8)2018 Jul 31.
Artigo
Inglês
| MEDLINE | ID: mdl-30065181
12.
Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptors.
Gut
; 66(5): 930-938, 2017 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26858343
13.
Targeting Liver Fibrosis with a Cell-penetrating Protease-activated Receptor-2 (PAR2) Pepducin.
J Biol Chem
; 291(44): 23188-23198, 2016 10 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27613872
14.
Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease.
Arterioscler Thromb Vasc Biol
; 36(1): 189-97, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26681756
15.
Allosteric Activation of a G Protein-coupled Receptor with Cell-penetrating Receptor Mimetics.
J Biol Chem
; 290(25): 15785-15798, 2015 Jun 19.
Artigo
Inglês
| MEDLINE | ID: mdl-25934391
16.
Tissue Concentrations of Vitamin K and Expression of Key Enzymes of Vitamin K Metabolism Are Influenced by Sex and Diet but Not Housing in C57Bl6 Mice.
J Nutr
; 146(8): 1521-7, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27385762
17.
G-protein-coupled receptors signaling pathways in new antiplatelet drug development.
Arterioscler Thromb Vasc Biol
; 35(3): 500-12, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25633316
18.
Matrix metalloproteases and PAR1 activation.
Blood
; 121(3): 431-9, 2013 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-23086754
19.
Noncanonical matrix metalloprotease-1-protease-activated receptor-1 signaling triggers vascular smooth muscle cell dedifferentiation and arterial stenosis.
J Biol Chem
; 288(32): 23105-15, 2013 Aug 09.
Artigo
Inglês
| MEDLINE | ID: mdl-23814055
20.
Mouse matrix metalloprotease-1a (Mmp1a) gives new insight into MMP function.
J Cell Physiol
; 229(12): 1875-80, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24737602