Detalhe da pesquisa
1.
Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs.
Int J Mol Sci
; 24(7)2023 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37047554
2.
Motifs in Natural Products as Useful Scaffolds to Obtain Novel Benzo[d]imidazole-Based Cannabinoid Type 2 (CB2) Receptor Agonists.
Int J Mol Sci
; 24(13)2023 Jun 30.
Artigo
Inglês
| MEDLINE | ID: mdl-37446093
3.
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor.
Molecules
; 28(13)2023 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37446625
4.
N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation.
Molecules
; 27(23)2022 Nov 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36500256
5.
Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo.
ACS Chem Neurosci
; 15(5): 955-971, 2024 03 06.
Artigo
Inglês
| MEDLINE | ID: mdl-38372253
6.
Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone.
Eur J Med Chem
; 269: 116298, 2024 Apr 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38493727
7.
Dual allosteric and orthosteric pharmacology of synthetic analog cannabidiol-dimethylheptyl, but not cannabidiol, on the cannabinoid CB2 receptor.
Biochem Pharmacol
; 218: 115924, 2023 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37972874