Detalhe da pesquisa
1.
Unraveling the complexity of amyloid polymorphism using gold nanoparticles and cryo-EM.
Proc Natl Acad Sci U S A
; 117(12): 6866-6874, 2020 03 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32161130
2.
A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α-synuclein research.
J Neurochem
; 153(1): 103-119, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31925956
3.
How specific are the conformation-specific α-synuclein antibodies? Characterization and validation of 16 α-synuclein conformation-specific antibodies using well-characterized preparations of α-synuclein monomers, fibrils and oligomers with distinct structures and morphology.
Neurobiol Dis
; 146: 105086, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32971232
4.
Structural characterization of amyloid fibrils from the human parathyroid hormone.
Biochim Biophys Acta
; 1854(4): 249-57, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25554227
5.
Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection.
J Virol
; 88(13): 7221-34, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24741080
6.
Artificial intelligence-coupled plasmonic infrared sensor for detection of structural protein biomarkers in neurodegenerative diseases.
Sci Adv
; 9(28): eadg9644, 2023 07 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37436975
7.
Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage.
Nat Neurosci
; 26(6): 983-996, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37248338
8.
Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases.
NPJ Parkinsons Dis
; 9(1): 161, 2023 Dec 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38062007
9.
A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity.
Sci Adv
; 8(17): eabn0044, 2022 04 29.
Artigo
Inglês
| MEDLINE | ID: mdl-35486726
10.
Disulfide conformation and design at helix N-termini.
Proteins
; 78(5): 1228-42, 2010 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19938155
11.
Chronic corticosterone aggravates behavioral and neuronal symptomatology in a mouse model of alpha-synuclein pathology.
Neurobiol Aging
; 83: 11-20, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31585362
12.
Author Correction: Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases.
NPJ Parkinsons Dis
; 10(1): 19, 2024 Jan 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38212333
13.
Solvent Removal Induces a Reversible ß-to-α Switch in Oligomeric Aß Peptide.
J Mol Biol
; 428(2 Pt A): 268-273, 2016 Jan 29.
Artigo
Inglês
| MEDLINE | ID: mdl-25975856
14.
Molecular architecture of Aß fibrils grown in cerebrospinal fluid solution and in a cell culture model of Aß plaque formation.
Amyloid
; 23(2): 76-85, 2016 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-26972581
15.
Structure and biomedical applications of amyloid oligomer nanoparticles.
ACS Nano
; 8(11): 11042-52, 2014 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-25337989
16.
Pattern recognition with a fibril-specific antibody fragment reveals the surface variability of natural amyloid fibrils.
J Mol Biol
; 408(3): 529-40, 2011 May 06.
Artigo
Inglês
| MEDLINE | ID: mdl-21376731
17.
Amyloid fibril recognition with the conformational B10 antibody fragment depends on electrostatic interactions.
J Mol Biol
; 405(2): 341-8, 2011 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-21059358