Pesquisa | Secretaria de Estado da Saúde

1.

Ribonucleotide Incorporation by Eukaryotic B-Family Replicases and Its Implications for Genome Stability.

Williams, Jessica S; Kunkel, Thomas A.

Annu Rev Biochem ; 91: 133-155, 2022 06 21.

Artigo Inglês | MEDLINE | ID: mdl-35287470

2.

Eukaryotic DNA Replication Fork.

Burgers, Peter M J; Kunkel, Thomas A.

Annu Rev Biochem ; 86: 417-438, 2017 06 20.

Artigo Inglês | MEDLINE | ID: mdl-28301743

3.

Celebrating DNA's Repair Crew.

Kunkel, Thomas A.

Cell ; 163(6): 1301-3, 2015 Dec 03.

Artigo Inglês | MEDLINE | ID: mdl-26638062

4.

Stepwise requirements for polymerases Î´ and Î¸ in theta-mediated end joining.

Stroik, Susanna; Carvajal-Garcia, Juan; Gupta, Dipika; Edwards, Alyssa; Luthman, Adam; Wyatt, David W; Dannenberg, Rachel L; Feng, Wanjuan; Kunkel, Thomas A; Gupta, Gaorav P; Hedglin, Mark; Wood, Richard; Doublié, Sylvie; Rothenberg, Eli; Ramsden, Dale A.

Nature ; 623(7988): 836-841, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-37968395

5.

Processing ribonucleotides incorporated during eukaryotic DNA replication.

Williams, Jessica S; Lujan, Scott A; Kunkel, Thomas A.

Nat Rev Mol Cell Biol ; 17(6): 350-63, 2016 06.

Artigo Inglês | MEDLINE | ID: mdl-27093943

6.

DNA Polymerase Delta Synthesizes Both Strands during Break-Induced Replication.

Donnianni, Roberto A; Zhou, Zhi-Xiong; Lujan, Scott A; Al-Zain, Amr; Garcia, Valerie; Glancy, Eleanor; Burkholder, Adam B; Kunkel, Thomas A; Symington, Lorraine S.

Mol Cell ; 76(3): 371-381.e4, 2019 11 07.

Artigo Inglês | MEDLINE | ID: mdl-31495565

7.

FEN nucleases: bind, bend, fray, cut.

Williams, R Scott; Kunkel, Thomas A.

Cell ; 145(2): 171-2, 2011 Apr 15.

Artigo Inglês | MEDLINE | ID: mdl-21496637

8.

Pif1 family helicases promote mutation avoidance during DNA replication.

Zhou, Zhi-Xiong; Follonier, Cindy; Lujan, Scott A; Burkholder, Adam B; Zakian, Virginia A; Kunkel, Thomas A.

Nucleic Acids Res ; 50(22): 12844-12855, 2022 12 09.

Artigo Inglês | MEDLINE | ID: mdl-36533450

9.

Probing the mechanisms of two exonuclease domain mutators of DNA polymerase Ïµ.

Dahl, Joseph M; Thomas, Natalie; Tracy, Maxwell A; Hearn, Brady L; Perera, Lalith; Kennedy, Scott R; Herr, Alan J; Kunkel, Thomas A.

Nucleic Acids Res ; 50(2): 962-974, 2022 01 25.

Artigo Inglês | MEDLINE | ID: mdl-35037018

10.

Ribonucleotide incorporation into DNA during DNA replication and its consequences.

Zhou, Zhi-Xiong; Williams, Jessica S; Lujan, Scott A; Kunkel, Thomas A.

Crit Rev Biochem Mol Biol ; 56(1): 109-124, 2021 02.

Artigo Inglês | MEDLINE | ID: mdl-33461360

11.

Eukaryotic Mismatch Repair in Relation to DNA Replication.

Kunkel, Thomas A; Erie, Dorothy A.

Annu Rev Genet ; 49: 291-313, 2015.

Artigo Inglês | MEDLINE | ID: mdl-26436461

12.

The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe-S cluster in DNA polymerase Î´.

Kiktev, Denis A; Dominska, Margaret; Zhang, Tony; Dahl, Joseph; Stepchenkova, Elena I; Mieczkowski, Piotr; Burgers, Peter M; Lujan, Scott; Burkholder, Adam; Kunkel, Thomas A; Petes, Thomas D.

Nucleic Acids Res ; 49(10): 5623-5636, 2021 06 04.

Artigo Inglês | MEDLINE | ID: mdl-34019669

13.

Topoisomerase I-mediated cleavage at unrepaired ribonucleotides generates DNA double-strand breaks.

Huang, Shar-Yin N; Williams, Jessica S; Arana, Mercedes E; Kunkel, Thomas A; Pommier, Yves.

EMBO J ; 36(3): 361-373, 2017 02 01.

Artigo Inglês | MEDLINE | ID: mdl-27932446

14.

Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA.

Williams, Jessica S; Smith, Dana J; Marjavaara, Lisette; Lujan, Scott A; Chabes, Andrei; Kunkel, Thomas A.

Mol Cell ; 49(5): 1010-5, 2013 Mar 07.

Artigo Inglês | MEDLINE | ID: mdl-23375499

15.

Ribonucleotides are signals for mismatch repair of leading-strand replication errors.

Lujan, Scott A; Williams, Jessica S; Clausen, Anders R; Clark, Alan B; Kunkel, Thomas A.

Mol Cell ; 50(3): 437-43, 2013 May 09.

Artigo Inglês | MEDLINE | ID: mdl-23603118

16.

The absence of the catalytic domains of Saccharomyces cerevisiae DNA polymerase Ïµ strongly reduces DNA replication fidelity.

Garbacz, Marta A; Cox, Phillip B; Sharma, Sushma; Lujan, Scott A; Chabes, Andrei; Kunkel, Thomas A.

Nucleic Acids Res ; 47(8): 3986-3995, 2019 05 07.

Artigo Inglês | MEDLINE | ID: mdl-30698744

17.

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.

Kaminski, Andrea M; Chiruvella, Kishore K; Ramsden, Dale A; Kunkel, Thomas A; Bebenek, Katarzyna; Pedersen, Lars C.

Nucleic Acids Res ; 47(17): 9410-9422, 2019 09 26.

Artigo Inglês | MEDLINE | ID: mdl-31435651

18.

Opportunities for new studies of nuclear DNA replication enzymology in budding yeast.

Garbacz, Marta A; Lujan, Scott A; Kunkel, Thomas A.

Curr Genet ; 66(2): 299-302, 2020 Apr.

Artigo Inglês | MEDLINE | ID: mdl-31493018

19.

SnapShot: DNA mismatch repair.

Larrea, Andres A; Lujan, Scott A; Kunkel, Thomas A.

Cell ; 141(4): 730.e1, 2010 May 14.

Artigo Inglês | MEDLINE | ID: mdl-20478261

20.

Aprataxin resolves adenylated RNA-DNA junctions to maintain genome integrity.

Tumbale, Percy; Williams, Jessica S; Schellenberg, Matthew J; Kunkel, Thomas A; Williams, R Scott.

Nature ; 506(7486): 111-5, 2014 Feb 06.

Artigo Inglês | MEDLINE | ID: mdl-24362567

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