Detalhe da pesquisa
1.
An inherited life-threatening arrhythmia model established by screening randomly mutagenized mice.
Proc Natl Acad Sci U S A
; 121(17): e2218204121, 2024 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38621141
2.
Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating.
Proc Natl Acad Sci U S A
; 119(32): e2201286119, 2022 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35925888
3.
NRSF-GNAO1 Pathway Contributes to the Regulation of Cardiac Ca2+ Homeostasis.
Circ Res
; 130(2): 234-248, 2022 01 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34875852
4.
Discovery and Structure-Activity Relationship of a Ryanodine Receptor 2 Inhibitor.
Chem Pharm Bull (Tokyo)
; 72(4): 399-407, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38644198
5.
Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca2+ Monitoring.
Mol Pharmacol
; 104(6): 275-286, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37678938
6.
Involvement of kallikrein-PAR2-proinflammatory pathway in severe trastuzumab-induced cardiotoxicity.
Cancer Sci
; 113(10): 3449-3462, 2022 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-35879248
7.
Differential effects of the formin inhibitor SMIFH2 on contractility and Ca2+ handling in frog and mouse cardiomyocytes.
Genes Cells
; 26(8): 583-595, 2021 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-34060165
8.
Loss-of-function mutations in cardiac ryanodine receptor channel cause various types of arrhythmias including long QT syndrome.
Europace
; 24(3): 497-510, 2022 03 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34661651
9.
Development of a water-soluble ryanodine receptor 1 inhibitor.
Bioorg Med Chem
; 74: 117027, 2022 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36223685
10.
Regulatory mechanisms of ryanodine receptor/Ca2+ release channel revealed by recent advancements in structural studies.
J Muscle Res Cell Motil
; 42(2): 291-304, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32040690
11.
Sudden death after inappropriate shocks of implantable cardioverter defibrillator in a catecholaminergic polymorphic ventricular tachycardia case with a novel RyR2 mutation.
J Electrocardiol
; 69: 111-118, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34656916
12.
The Ryanodine Receptor as a Sensor for Intracellular Environments in Muscles.
Int J Mol Sci
; 22(19)2021 Oct 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34639137
13.
Co-Phenotype of Left Ventricular Non-Compaction Cardiomyopathy and Atypical Catecholaminergic Polymorphic Ventricular Tachycardia in Association With R169Q, a Ryanodine Receptor Type 2 Missense Mutation.
Circ J
; 84(2): 226-234, 2020 01 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31875585
14.
A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain.
J Pharmacol Sci
; 140(1): 109-112, 2019 May.
Artigo
Inglês
| MEDLINE | ID: mdl-31155393
15.
Efficient High-Throughput Screening by Endoplasmic Reticulum Ca2+ Measurement to Identify Inhibitors of Ryanodine Receptor Ca2+-Release Channels.
Mol Pharmacol
; 94(1): 722-730, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29674523
16.
Therapeutic potential of ghrelin and des-acyl ghrelin against chemotherapy-induced cardiotoxicity.
Endocr J
; 64(Suppl.): S35-S39, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28652542
17.
Genotype-Phenotype Correlations of Malignant Hyperthermia and Central Core Disease Mutations in the Central Region of the RYR1 Channel.
Hum Mutat
; 37(11): 1231-1241, 2016 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27586648
18.
Nitric oxide-induced calcium release via ryanodine receptors regulates neuronal function.
EMBO J
; 31(2): 417-28, 2012 Jan 18.
Artigo
Inglês
| MEDLINE | ID: mdl-22036948
19.
A dominant negative form of inositol 1,4,5-trisphosphate receptor induces metacyclogenesis and increases mitochondrial density in Trypanosoma cruzi.
Biochem Biophys Res Commun
; 466(3): 475-80, 2015 Oct 23.
Artigo
Inglês
| MEDLINE | ID: mdl-26367178
20.
Inositol 1,4,5-trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist Trypanosoma cruzi.
Mol Microbiol
; 87(6): 1133-50, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23320762