Detalhe da pesquisa
1.
X-CHIME enables combinatorial, inducible, lineage-specific and sequential knockout of genes in the immune system.
Nat Immunol
; 25(1): 178-188, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38012416
2.
Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway.
Cell
; 184(17): 4495-4511.e19, 2021 08 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34289345
3.
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity.
Cell
; 183(7): 1848-1866.e26, 2020 12 23.
Artigo
Inglês
| MEDLINE | ID: mdl-33301708
4.
LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade.
Cell
; 174(3): 549-563.e19, 2018 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29937226
5.
PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity.
Nat Immunol
; 20(10): 1335-1347, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31527834
6.
Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling.
Nat Immunol
; 20(12): 1668-1680, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31636464
7.
Author Correction: Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade.
Nat Immunol
; 20(11): 1556, 2019 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-31582823
8.
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade.
Nat Immunol
; 20(3): 326-336, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30778252
9.
Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance.
Nature
; 617(7960): 377-385, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37138075
10.
Publisher Correction: Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance.
Nature
; 618(7966): E27, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37264079
11.
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.
Nature
; 547(7664): 413-418, 2017 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28723893
12.
Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade.
Proc Natl Acad Sci U S A
; 116(34): 16971-16980, 2019 08 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31375632
13.
Inhibitors of the PD-1 Pathway in Tumor Therapy.
J Immunol
; 200(2): 375-383, 2018 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29311378
14.
Framework for in vivo T cell screens.
J Exp Med
; 221(4)2024 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38411617
15.
Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade.
Cancer Discov
; 13(12): 2566-2583, 2023 12 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37728660
16.
CRISPR Screens to Identify Regulators of Tumor Immunity.
Annu Rev Cancer Biol
; 6: 103-122, 2022 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-35989706
17.
Batf-mediated epigenetic control of effector CD8+ T cell differentiation.
Sci Immunol
; 7(68): eabi4919, 2022 02 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35179948
18.
Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells.
Cancer Immunol Res
; 9(2): 184-199, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33277233
19.
Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses.
Sci Transl Med
; 13(581)2021 02 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33597266
20.
T Cell Activation Depends on Extracellular Alanine.
Cell Rep
; 28(12): 3011-3021.e4, 2019 09 17.
Artigo
Inglês
| MEDLINE | ID: mdl-31533027