Detalhe da pesquisa
1.
Uniformity of glycyl bridge lengths in the mature cell walls of fem mutants of methicillin-resistant Staphylococcus aureus.
J Bacteriol
; 195(7): 1421-7, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23335411
2.
Dysregulation of bacterial proteolytic machinery by a new class of antibiotics.
Nat Med
; 11(10): 1082-7, 2005 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-16200071
3.
Human pharmacokinetics and safety profile of finafloxacin, a new fluoroquinolone antibiotic, in healthy volunteers.
Antimicrob Agents Chemother
; 55(9): 4386-93, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21709093
4.
In vitro spectrum of activity of finafloxacin, a novel, pH-activated fluoroquinolone, under standard and acidic conditions.
Antimicrob Agents Chemother
; 55(9): 4394-7, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21709094
5.
Antibacterial activity of finafloxacin under different pH conditions against isogenic strains of Escherichia coli expressing combinations of defined mechanisms of fluoroquinolone resistance.
J Antimicrob Chemother
; 65(12): 2530-3, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-20940181
6.
Characterization of peptidoglycan in fem-deletion mutants of methicillin-resistant Staphylococcus aureus by solid-state NMR.
Biochemistry
; 48(14): 3100-8, 2009 Apr 14.
Artigo
Inglês
| MEDLINE | ID: mdl-19309106
7.
Daptomycin versus Friulimicin B: in-depth profiling of Bacillus subtilis cell envelope stress responses.
Antimicrob Agents Chemother
; 53(4): 1619-23, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19164157
8.
In vitro and in vivo validation of ligA and tarI as essential targets in Staphylococcus aureus.
Antimicrob Agents Chemother
; 52(12): 4470-4, 2008 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-18809938
9.
The impact of transcriptome and proteome analyses on antibiotic drug discovery.
Curr Opin Microbiol
; 7(5): 451-9, 2004 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-15451499
10.
Antibacterial research and development in the 21(st) Century--an industry perspective of the challenges.
Curr Opin Microbiol
; 7(5): 445-50, 2004 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-15451498
11.
Cell wall targets in methicillin-resistant staphylococci.
Drug Resist Updat
; 2(5): 319-325, 1999 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-11504506
12.
Prospects and challenges in anti-infective research and development: new drugs and approaches.
Curr Opin Pharmacol
; 8(5): 519-21, 2008 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-18848903
13.
Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria.
Angew Chem Int Ed Engl
; 39(21): 3823-3828, 2000 Nov 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29711708
14.
New antibiotics for antibiotic-resistant bacteria.
F1000 Biol Rep
; 1: 40, 2009 May 28.
Artigo
Inglês
| MEDLINE | ID: mdl-20948644
15.
Characterization of a daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus strain in a patient with endocarditis.
Antimicrob Agents Chemother
; 51(9): 3445-8, 2007 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-17620372
16.
Bacterial proteomics and its role in antibacterial drug discovery.
Mass Spectrom Rev
; 24(4): 549-65, 2005.
Artigo
Inglês
| MEDLINE | ID: mdl-15389844
17.
Staphylococcus aureus NfrA (SA0367) is a flavin mononucleotide-dependent NADPH oxidase involved in oxidative stress response.
J Bacteriol
; 187(7): 2249-56, 2005 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-15774866
18.
Proteomic approach to understanding antibiotic action.
Antimicrob Agents Chemother
; 47(3): 948-55, 2003 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-12604526
19.
Specific and potent inhibition of NAD+-dependent DNA ligase by pyridochromanones.
J Biol Chem
; 278(41): 39435-42, 2003 Oct 10.
Artigo
Inglês
| MEDLINE | ID: mdl-12867414
20.
Increased glycan chain length distribution and decreased susceptibility to moenomycin in a vancomycin-resistant Staphylococcus aureus mutant.
Antimicrob Agents Chemother
; 46(1): 75-81, 2002 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-11751114