Detalhe da pesquisa
1.
Fluorophosphonates on-Demand: A General and Simplified Approach toward Fluorophosphonate Synthesis.
Chembiochem
; 22(10): 1769-1774, 2021 05 14.
Artigo
Inglês
| MEDLINE | ID: mdl-33491295
2.
Strategies toward optimization of the metabolism of a series of serotonin-4 partial agonists: investigation of azetidines as piperidine isosteres.
Xenobiotica
; 46(12): 1112-1121, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26947511
3.
Discovery of N-X anomeric amides as electrophilic halogenation reagents.
Nat Chem
; 2024 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38769366
4.
Intramolecular Ring-Opening Decomposition of Aryl Azetidines.
ACS Med Chem Lett
; 12(10): 1585-1588, 2021 Oct 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34676040
5.
Discovery of Selective M4 Muscarinic Acetylcholine Receptor Agonists with Novel Carbamate Isosteres.
ACS Med Chem Lett
; 10(6): 941-948, 2019 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31223452
6.
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, ß-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation.
J Med Chem
; 61(10): 4476-4504, 2018 05 24.
Artigo
Inglês
| MEDLINE | ID: mdl-29613789
7.
The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging.
J Med Chem
; 60(20): 8538-8551, 2017 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-28957634
8.
Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK).
J Med Chem
; 60(18): 7835-7849, 2017 09 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28853885
9.
Correction to Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor.
J Med Chem
; 61(8): 3753, 2018 04 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29624389