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ABSTRACT: Accurate diagnosis is a key strategy for controlling and preventing malaria. Regular evaluation of the performance of malaria microscopy diagnosis is essential to ensure its high quality. This study aims to assess the accuracy of malaria microscopy at selected public health facilities on the border of Indonesia and Timor-Leste. The design of this research is observational with a cross-sectional approach, conducted at five public health centers located on the Indonesia Timor-Leste border from July to September 2022. Stained slides were collected from patients with a fever (≥37°C). These stained slides were then examined for malaria diagnosis. The results revealed that all five public health centers showed perfect or nearly perfect agreement with the reference microscopist regarding malaria detection by microscopy (κ =0.9-1). To maintain the high quality of malaria microscopy diagnosis, it is imperative to conduct regular training, monitoring, and evaluation.
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Malária , Microscopia , Humanos , Microscopia/métodos , Estudos Transversais , Indonésia/epidemiologia , Timor-Leste/epidemiologia , Malária/diagnóstico , Malária/epidemiologia , Feminino , Masculino , Saúde PúblicaRESUMO
Background: Plastic waste that ends up in the ocean can undergo a degradation process into small plastic particles measuring 5 mm called microplastics. The presence of microplastics in the sea can contaminate marine products such as sea salt. Microplastics in the salt consumed by humans can cause adverse health effects. This study aims to determine the difference in the content of microplastics in commercial salt and local salt from the semiringkai coast in Kupang City and Kupang Regency. Material and Methods: This research is an observational analytical study with a comparative analysis design. The method used is laboratory observation using a microscope. This study used 10 salt samples which were divided into 2 groups, namely the commercial salt group and the local salt group, each consisting of 5 salt samples. Samples were taken using non-probability sampling method with purposive sampling technique. Data were analyzed univariately and bivariately using the independent T-comparison test. Results: The results of the analysis test in this study were P = 0.065 (P > 0.05). Conclusion: There is a content of microplastic in commercial salt and local center salt of the semiringkai coast in Kupang City and Kupang Regency with an average that is not significantly different.
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Introduction: This study aimed to evaluate the relation between happiness perception of children and quality of sleep, appetite, dietary intake and nutritional status. Materials and Methods: A cross-sectional study evaluating happiness, quality of sleep, appetite, dietary intake and nutritional status in 296 Indonesian children less than five-years of age. Results: There was no significant difference on perceived happiness between urban and rural areas (P = 0.087). The proportion of children that are perceived as happy by mothers (55.1%) is significantly higher (p < 0.001) as perceived as happy by fathers (50.7%). A significant lower dietary energy intake with a higher percentage of dietary protein to total energy intake was observed among those children that are perceived as happy. However, after adjusted to body weight, there was no significant difference in the amount of protein intake between those perceived as happy and unhappy. Amongst the nutritional status indicators, this study found a significantly higher Height-for-Age Z score among the children that perceived as happy. Conclusion: Height-for-age Z score and dietary protein intake in children aged 2-5 years are associated with quality of sleep and appetite, and may therefore affect children's happiness. Not only parental care but also appropriate nutrient intakes influence the child's happiness.
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Centrotemporal spikes are the EEG marker of Rolandic epilepsy, while ictus emeticus is one of the main seizure manifestations of Panayiotopoulos syndrome. Ictus emeticus has not been reported in Rolandic epilepsy. Out of a population of 1340 children with focal afebrile seizures we studied 24 children who had emetic manifestations in at least one seizure and centrotemporal spikes in at least one EEG. They were of normal neurological status and had a follow-up of at least two years after the last seizure. All children had sleep EEG following sleep deprivation. Two groups of patients were identified. Group A (12 patients) with EEG centrotemporal spikes only and group B (12 patients) with centrotemporal spikes and spikes in other locations. In 21 patients, ictal emetic manifestations culminated in vomiting and in three only nausea or retching occurred. The commonest presentation was ictus emeticus at onset followed by deviation of the eyes or staring, loss of contact and floppiness. In 79%, seizures occurred during sleep. Autonomic status epilepticus occurred in 37.5%. The mean age at onset was 5.3 years. Overall analysis of the clinical and EEG data points out that the vast majority of these patients primarily suffer from Panayiotopoulos syndrome. Twenty patients (83%) had ictal semiology typical of Panayiotopoulos syndrome, but five also had concurrent Rolandic symptoms and four later developed pure Rolandic seizures. The other four patients (17%) had typical Rolandic seizures with concurrent ictus emeticus. These findings suggest a link between Rolandic epilepsy and Panayiotopoulos syndrome, the two most important phenotypes of the benign childhood seizure susceptibility syndrome.
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Eletroencefalografia , Epilepsia Rolândica/fisiopatologia , Convulsões/fisiopatologia , Vômito/fisiopatologia , Adolescente , Idade de Início , Sistema Nervoso Autônomo/fisiopatologia , Criança , Diagnóstico Diferencial , Epilepsia Rolândica/complicações , Feminino , Febre/complicações , Seguimentos , Humanos , Masculino , Prognóstico , Convulsões/complicações , Estado Epiléptico/fisiopatologia , Síndrome , Vômito/etiologiaRESUMO
Childhood malnutrition remains a public health issue in Indonesia with a national prevalence of wasting of 13% and stunting of 36%. In rural areas nutritional status depends on local agriculture and may fluctuate in relation to harvest time. The aim of this study was to characterise seasonal variations in nutritional status in two resettlement villages in the Oesao district, Nusa Tenggara Timur. A cross sectional study was conducted in a convenience sample of children after the wet season (March). Children aged 6 to 60 months were assessed for nutritional status using anthropometric and biochemical measures. A subset of these children was re-assessed for anthropometry after the dry season (November). Weight-for-height z scores improved significantly from mean±SD of -1.7± 0.9 in March to -1.3±0.9 in November (p<0.001). There was no significant change in height between seasons. Prevalence of wasting, (weight-for-height z score <-2), was 42% in March and 19% in November (p<0.001). However, stunting rates increased significantly from 42% in March to 45% in November (p<0.001). Thirty six per cent of children were anaemic (Hb level <11 mg/100 mL), 68% were vitamin A deficient (plasma vitamin A level <0.8 µmol/L) and 50% were zinc deficient (plasma zinc <9.94 µmol/L). All children except one were positive for intestinal parasites. These data indicate seasonal changes in anthropometry with inconsistent effects depending on the anthropometric index measured. Wasting and stunting were higher than the national average, alongside high rates of anaemia, zinc and vitamin A deficiencies.
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Estado Nutricional , Estações do Ano , Anemia/epidemiologia , Antropometria , Estatura , Peso Corporal , Pré-Escolar , Estudos Transversais , Dieta , Feminino , Transtornos do Crescimento/epidemiologia , Hemoglobinas/análise , Humanos , Indonésia/epidemiologia , Lactente , Enteropatias Parasitárias/epidemiologia , Masculino , Deficiência de Vitamina A/epidemiologia , Zinco/deficiênciaRESUMO
PURPOSE: To discuss and propose a definition of autonomic status epilepticus (SE), describe its clinical and EEG features, and review what is known about its epidemiology, pathophysiology, differential diagnosis, and management. METHODS: An international consortium of established researchers in the field was identified from their published work, agreed the purpose of the project, searched the literature, and, by use of e-mail communication, agreed the consensus document. RESULTS: Autonomic SE is a condition lasting at least 30 min and characterized by epileptic activity causing altered autonomic function of any type at seizure onset or in which manifestations consistent with altered autonomic function are prominent (quantitatively dominant or clinically important) even if not present at seizure onset. It is best described, and probably most commonly encountered in children, with Panayiotopoulos syndrome. However, it also occurs in children with symptomatic epilepsies and, exceptionally, in adults. Its pathogenesis and most appropriate management are poorly understood. CONCLUSIONS: It is hoped that this document will help clinical recognition of Autonomic SE, reduce misdiagnosis, and promote further interest and studies into what has been a relatively neglected area.
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Doenças do Sistema Nervoso Autônomo/diagnóstico , Epilepsias Parciais/diagnóstico , Epilepsia Rolândica/diagnóstico , Estado Epiléptico/diagnóstico , Adulto , Fatores Etários , Doenças do Sistema Nervoso Autônomo/classificação , Doenças do Sistema Nervoso Autônomo/fisiopatologia , Encéfalo/fisiopatologia , Córtex Cerebral/fisiopatologia , Criança , Diagnóstico Diferencial , Eletroencefalografia/estatística & dados numéricos , Epilepsias Parciais/classificação , Epilepsias Parciais/fisiopatologia , Epilepsia Rolândica/classificação , Epilepsia Rolândica/fisiopatologia , Humanos , Cooperação Internacional , Estado Epiléptico/classificação , Estado Epiléptico/fisiopatologia , Síndrome , Terminologia como AssuntoRESUMO
PURPOSE: To determine prevalence, clinical, EEG features, and prognosis of Panayiotopoulos syndrome and to examine the proposition that clinical manifestations are more important than EEG findings. METHODS: We analyzed retrospectively the clinical and EEG records of 1,340 children with one or more focal seizures seen in the last 18 years, supplemented with a prospective study from 1998. Panayiotopoulos syndrome was defined by clinical criteria, mainly ictal emesis, irrespective of EEG findings. RESULTS: We analyzed 43 of 90 patients with Panayiotopoulos syndrome who were seizure free >2 years. Girls predominated. Mean age at first seizure was 5 years. Seizures consisted mainly of autonomic manifestations; ictal emesis was often the first symptom, culminating in vomiting in 86%. Of nonautonomic manifestations, lateral eye deviation was the most common; visual symptoms were exceptional. Impairment of consciousness ensued in all seizures, half of which ended with hemi or generalized convulsions. Nearly 46.5% of cases had at least one seizure >30 min, constituting autonomic status epilepticus. Seizures during sleep (84%) were more common than those in wakefulness. EEG showed occipital spikes in 29 patients. Of the other 14 cases, five had extraoccipital abnormalities or brief generalized discharges, and nine had normal awake and sleep EEG. Prognosis was excellent. All 43 children have been free of seizures for > or =2 years, 53% having a single seizure, and 47%, an average two to three seizures. CONCLUSIONS: Panayiotopoulos syndrome is common and needs wider recognition. EEG shows occipital or extraoccipital abnormalities, is normal in one third of patients, and does not determine clinical manifestations or prognosis, which is excellent despite the high prevalence of lengthy seizures.