Detalhe da pesquisa
1.
Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists.
Bioorg Med Chem
; 24(6): 1384-91, 2016 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26897089
2.
Regulation of sphingomyelin phosphodiesterase acid-like 3A gene (SMPDL3A) by liver X receptors.
Mol Pharmacol
; 82(4): 719-27, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22810003
3.
Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring.
Bioorg Med Chem Lett
; 22(10): 3392-7, 2012 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22542194
4.
The ligand-dependent interaction of mineralocorticoid receptor with coactivator and corepressor peptides suggests multiple activation mechanisms.
Mol Endocrinol
; 19(6): 1460-73, 2005 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-15761029
5.
Influence of sub-chronic selective 11ß-hydroxysteroid dehydrogenase 1 inhibition on the hypothalamic-pituitary-adrenal axis in female cynomolgus monkeys.
Eur J Pharmacol
; 789: 68-74, 2016 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27393460
6.
The liver X receptors.
Curr Opin Investig Drugs
; 6(9): 934-43, 2005 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-16187693
7.
Molecular mechanisms of mineralocorticoid receptor antagonism by eplerenone.
Mini Rev Med Chem
; 5(8): 709-18, 2005 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-16101407
8.
Liver X receptors interact with corepressors to regulate gene expression.
Mol Endocrinol
; 17(6): 1019-26, 2003 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-12663743
9.
Repression of p65 transcriptional activation by the glucocorticoid receptor in the absence of receptor-coactivator interactions.
Mol Endocrinol
; 18(1): 53-62, 2004 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-14551261
10.
The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor.
Mol Endocrinol
; 16(7): 1590-7, 2002 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-12089353
11.
Induction of human liver X receptor alpha gene expression via an autoregulatory loop mechanism.
Mol Endocrinol
; 16(3): 506-14, 2002 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-11875109
12.
Pharmacological characterization of the selective 11ß-hydroxysteroid dehydrogenase 1 inhibitor, BI 135585, a clinical candidate for the treatment of type 2 diabetes.
Eur J Pharmacol
; 746: 50-5, 2015 Jan 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25445047
13.
Multiplexing nuclear receptors for agonist identification in a cell-based reporter gene high-throughput screen.
J Biomol Screen
; 8(3): 239-46, 2003 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-12857377
14.
Liver X receptors and atherosclerosis.
IDrugs
; 7(6): 563-9, 2004 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-15197661
15.
The medicinal chemistry of liver X receptor (LXR) modulators.
J Med Chem
; 57(17): 7182-205, 2014 Sep 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24832115
16.
An activin receptor-like kinase 5 inhibitor reduces collagen deposition in a rat dermal incision wound healing model.
Plast Reconstr Surg
; 128(5): 451e-459e, 2011 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22030504
17.
Steroidogenic factor 1: an essential mediator of endocrine development.
Recent Prog Horm Res
; 57: 19-36, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-12017543