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1.
IEEE Trans Biomed Eng ; 42(7): 694-8, 1995 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-7622152

RESUMO

There are a number of potential advantages to be gained by using an array of applicators in hyperthermia treatments compared with single applicator systems. These advantages include the possibility of greater spatial control of power deposition and conformability to nonplanar sites. Arrays of applicators can be driven either coherently or incoherently. In the case of coherent operation, an added advantage is the ability to steer power deposition by varying the phases of the antennas. In this study, we investigated the relative merits of the two modes of operation when a 2 x 2 planar array of current sheet applicators is used. The effective field size (EFS) of the array was calculated using a Gaussian beam representation of the applicators on a layered model in which the fat layer had its thickness varied. Good agreement was obtained between the square of the electric field distribution (E2) and quantitative experimental results. It is shown that when the planar array is used with a fat layer greater than about 2 mm present, it should be driven incoherently as this results in a significantly larger EFS than that obtained when the array is driven coherently.


Assuntos
Hipertermia Induzida/instrumentação , Hipertermia Induzida/métodos , Modelos Biológicos , Humanos
2.
Int J Hyperthermia ; 12(2): 255-69, 1996.
Artigo em Inglês | MEDLINE | ID: mdl-8926393

RESUMO

The Effective Field Sizes (EFS) and the Effective Heating Depths (EDH) of Contact Flexible Microstrip Applicators (CFMA), tuned at a frequency of 434 MHz, were determined on two fat/muscle phantoms. One phantom was box-shaped with a flat top layer of 1 cm thick artificial fat and the other one a tube of which the cross-section was elliptically shaped (25 x 36 cm) having a fat equivalent shell of 1 cm thick. For the muscle material a 6 g/l saline (NaCl) solution was used. On the flat rectangular phantom, the effective field size at 1 cm depth in saline was measured to be 4.7 x 13.5 cm, 17.5 x 17.7 cm and 12.5 x 14.0 cm for the 1H-applicator, the 3H-applicator and the 5H-applicator, respectively. For the 3H-and the 5H-applicator, the Specific absorption rate (SAR) distribution at 1 cm depth showed a single maximum of SAR for a thin bolus, which split into two separate "hot spots' for a thicker bolus. The Effective Heating Depths in the phantom with a flat surface were of the order of that of a plane wave (approximately 1.4 cm), whereas a larger EHD of 2.4 cm was achieved below the 3H-applicator bent to fit the elliptical phantom. Due to the large effective field size and the "flatness' of the SAR distribution, the applicators 3H and 5H are suitable to adequately treat large superficial tumours.


Assuntos
Hipertermia Induzida/métodos , Gorduras/metabolismo , Temperatura Alta , Hipertermia Induzida/instrumentação , Micro-Ondas , Modelos Biológicos
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