Detalhe da pesquisa
1.
Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.
Nature
; 552(7683): 116-120, 2017 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29186113
2.
Emergence of MET hyper-amplification at progression to MET and BRAF inhibition in colorectal cancer.
Br J Cancer
; 117(3): 347-352, 2017 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-28654634
3.
Targeted knock-in of the polymorphism rs61764370 does not affect KRAS expression but reduces let-7 levels.
Hum Mutat
; 35(2): 208-14, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24282149
4.
Mutational profiling of kinases in glioblastoma.
BMC Cancer
; 14: 718, 2014 Sep 26.
Artigo
Inglês
| MEDLINE | ID: mdl-25256166
5.
Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer.
Genome Med
; 16(1): 15, 2024 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38243308
6.
Preclinical efficacy of carfilzomib in BRAF-mutant colorectal cancer models.
Mol Oncol
; 18(6): 1552-1570, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38348572
7.
Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells.
Cell Rep Med
; 5(2): 101376, 2024 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38228147
8.
KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.
Int J Cancer
; 133(5): 1259-65, 2013 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23404247
9.
Dual VEGFA/BRAF targeting boosts PD-1 blockade in melanoma through GM-CSF-mediated infiltration of M1 macrophages.
Mol Oncol
; 17(8): 1474-1491, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37183363
10.
Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance.
Cancer Cell
; 41(1): 196-209.e5, 2023 01 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36584674
11.
A modified fluctuation-test framework characterizes the population dynamics and mutation rate of colorectal cancer persister cells.
Nat Genet
; 54(7): 976-984, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35817983
12.
Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer.
Clin Cancer Res
; 28(17): 3874-3889, 2022 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35881546
13.
Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses.
Proc Natl Acad Sci U S A
; 105(52): 20864-9, 2008 Dec 30.
Artigo
Inglês
| MEDLINE | ID: mdl-19106301
14.
CD4 T Cell-Dependent Rejection of Beta-2 Microglobulin Null Mismatch Repair-Deficient Tumors.
Cancer Discov
; 11(7): 1844-1859, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33653693
15.
The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.
Acta Neuropathol
; 119(4): 487-94, 2010 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-20127344
16.
Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab.
JAMA
; 304(16): 1812-20, 2010 Oct 27.
Artigo
Inglês
| MEDLINE | ID: mdl-20978259
17.
High-dose vitamin C enhances cancer immunotherapy.
Sci Transl Med
; 12(532)2020 02 26.
Artigo
Inglês
| MEDLINE | ID: mdl-32102933
18.
Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer.
Cancers (Basel)
; 12(3)2020 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32183295
19.
EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer.
Cancer Discov
; 10(8): 1129-1139, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32430388
20.
Mutational profiling of cancer candidate genes in glioblastoma, melanoma and pancreatic carcinoma reveals a snapshot of their genomic landscapes.
Hum Mutat
; 30(2): E451-9, 2009 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-19058223